Insights & Discussion
Sesame consumption significantly increases enzymatic (superoxide dismutase, glutathione peroxidase, catalase) and non-enzymatic (vitamin C, vitamin E, β-carotene, and glutathione) antioxidants.
Meta-analyses revealed that sesame consumption significantly increases enzymatic (superoxide dismutase, glutathione peroxidase, catalase) and non-enzymatic (vitamin C, vitamin E, β-carotene, and glutathione) antioxidants. However, no significant effect was observed on malondialdehyde (MDA), total antioxidant capacity and α-tocopherol levels. It was shown that MDA levels significantly decreases only when sesame seeds were used for supplementation. Sesame consumption is associated with improved oxidative status. High quality randomized controlled clinical trials from diverse regions are still needed.
Discover Related Insights
Green tea supplementation improves total antioxidant capacity and impacts oxidative stress based on dose levels in adults.
2021 Antioxidants Effect of Green Tea Supplementation on Antioxidant Status in Adults: A Systematic Review and Meta-Analysis of Randomized Clinical Trials Rasaei N, Asbaghi O, Samadi M, Setayesh L, Bagheri R, Gholami F, et al.
Systematic Review Antioxidant Green Tea Oxidative Stress
The research's methodology involved a systematic search of research materials published in English language up to 21 August 2021. Recognized online databases such as Scopus, PubMed, Embase, and ISI Web of Science were utilized with the appropriate keywords. The study focused on randomized controlled trials that evaluated green tea supplementation, and its relationship with malondialdehyde and total antioxidant capacity in adults. A random-effects model quantified the difference, and the researchers carried out meta-regression and non-linear dose-response analyses to investigate the association between the quantity of green tea consumed and the duration of the intervention.
The research analysed the results obtained from sixteen randomized controlled trials, which amount to seventeen study arms comprising a total of 760 participants. The study found that green tea supplementation did have significant effects on total antioxidant capacity, and these effects were chiefly linked to gender and body mass index. However, the results showed that these effects were not significant in cases of low-dose supplementation and obese individuals. On the other hand, no relationship was found between malondialdehyde and green tea supplementation in any subgroup. Nonetheless, meta-regression analyses indicated an inverse linear connection between the change in MDA and the dosage of green tea.