Research Articles
Published research studies are articles that present the findings of original research that has undergone a peer-review process and has been made publicly available in scholarly journals, books or other media.
How to submit an article:
- Registered users can submit any published journal article that has a unique DOI (Digital Object Identifier) name or link to Research Hub.
- For example, you can paste the full DOI link:
https://doi.org/10.1109/5.771073
or just the DOI name: 10.1109/5.771073
into the field above and click submit.
- The person who is first to submit a valid article to Research Hub will forever be credited for it, and every article submission earns you +6 Research Points.
Chinese Herbal Medicine in Treatment of Spinal Cord Injury: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
2020 Jan 5 The American Journal of Chinese Medicine Zheng Y, Qi S, Wu F, Hu J, Zhong R, Hua C, et al.
Systematic Review Meta-Analysis Bu Yang Huan Wu Spinal Cord Injury Current evidence suggests that Chinese herbal medicine is an effective and safe treatment for spinal cord injury and could be treated as a complementary and alternative option with few side effects.
Treatment with the traditional Chinese medicine BuYang HuanWu Tang induces alterations that normalize the microbiome in ASD patients
2020 Jan Bioscience of Microbiota, Food and Health ZHANG Y, HU N, CAI Q, ZHANG F, ZOU J, LIU Y, et al.
This study characterized the alterations of the intestinal microbiome in children with ASD and its normalization after TCM treatment (TCMT), which may provide novel insights into the diagnosis and therapy of ASD.
Clinical Study Bu Yang Huan Wu Children's Health
Research Insights
Insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.
Current evidence suggests that Chinese herbal medicine is an effective and safe treatment for spinal cord injury and could be treated as a complementary and alternative option with few side effects.
Systematic Review Spinal Cord Injury
A total of 26 studies involving 1961 participants were included in this study. No serious heterogeneity or publication bias was observed across each study. The results showed that significant improvements of the American Spinal Injury Association (ASIA)-grading improvement rate, clinical effective rate, ASIA motor score, ASIA sensory score (total), ASIA sensory score (light touch) ASIA sensory score (pinprick) and activities of daily living (ADL) score in CHM group compared with the control group.
Among the CHM groups, Buyang Huanwu decoction was the most frequently prescribed herbal formula, while Astragalus membranaceus was the most commonly used single herb. In addition, there were no serious and permanent adverse effects in the two groups.
The methodological quality of the most included RCTs was poor and the quality of evidence for the main outcomes was from very low to moderate according to the GRADE system. Current evidence suggests that CHM is an effective and safe treatment for SCI and could be treated as a complementary and alternative option with few side effects.
However, considering the low quality, small size, and high risk of the studies identified in this meta-analysis, higher methodological quality, rigorously designed RCTs with large sample sizes are needed to confirm the results.
View Article
Clinical Trials
Clinical trials are research studies that involve people and are conducted to evaluate the safety and efficacy of new treatments or interventions, such as drugs, medical devices, or behavioural therapies.
Presentation Slides
Chinese Medicine Research Hub
Systematic Review
Current evidence suggests that Chinese herbal medicine is an effective and safe treatment for spinal cord injury and could be treated as a complementary and alternative option with few side effects.
2020 The American Journal of Chinese Medicine Chinese Herbal Medicine in Treatment of Spinal Cord Injury: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Zheng Y, Qi S, Wu F, Hu J, Zhong R, Hua C, Jiang D, Quan R
Executive Summary
Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Bu Yang Huan Wu" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.
Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Bu Yang Huan Wu" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.
Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Bu Yang Huan Wu" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.
A Systematic Review published in 2020 in the journal The American Journal of Chinese Medicine found that Current evidence suggests that Chinese herbal medicine is an effective and safe treatment for spinal cord injury and could be treated as a complementary and alternative option with few side effects. A total of 26 studies involving 1961 participants were included in this study. No serious heterogeneity or publication bias was observed across each study. The results showed that significant improvements of the American Spinal Injury Association (ASIA)-grading improvement rate, clinical effective rate, ASIA motor score, ASIA sensory score (total), ASIA sensory score (light touch) ASIA sensory score (pinprick) and activities of daily living (ADL) score in CHM group compared with the control group.
Among the CHM groups, Buyang Huanwu decoction was the most frequently prescribed herbal formula, while Astragalus membranaceus was the most commonly used single herb. In addition, there were no serious and permanent adverse effects in the two groups.
The methodological quality of the most included RCTs was poor and the quality of evidence for the main outcomes was from very low to moderate according to the GRADE system. Current evidence suggests that CHM is an effective and safe treatment for SCI and could be treated as a complementary and alternative option with few side effects.
However, considering the low quality, small size, and high risk of the studies identified in this meta-analysis, higher methodological quality, rigorously designed RCTs with large sample sizes are needed to confirm the results.