Xia Ku Cao
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Also known as: Prunella vulgaris
Published research studies are articles that present the findings of original research that has undergone a peer-review process and has been made publicly available in scholarly journals, books or other media.

Emerging therapeutic role of Prunella vulgaris in thyroid disease
2022 Jul Chinese Herbal Medicines Zhang W, Wuhan Q, Na M, Hu R, Mu Q, Bao X
Herbs such as P. vulgaris have great potential for treating thyroid disorders owing to their anti-oxidation and immunological effects and are frequently used as ingredients in herbal recipes. P. vulgaris is thought to combat drug toxicity within the body, therefore its own active ingredients have attracted much attention. The use of P. vulgaris with other drugs resulted in significant elimination of swollen nodules, reduced inflammatory response, and improved thyroid function. These effects of P. vulgaris benefit the clinical treatment of thyroid disease while having reduced drug-induced side effects and improved therapeutic effects. However, with only a few studies presenting treatment with Prunella vulgaris alone, further investigation is needed to to explore the physiological mechanisms.
Review Article Xia Ku Cao
Safety and efficacy of Prunella vulgaris preparation in adjuvant treatment of thyroid nodules
2021 Oct 15 Medicine Han Q, Xu N, Chen B, Wu W, Sheng L
PV combined with levothyroxine sodium tablets or thyroxin tablets has more benefits for thyroid nodules, further improving the clinical efficiency, reducing the diameter of nodules and reducing the occurrence of adverse reactions. However, the quality of these studies is uncertain, and higher quality and more RCTs are needed to provide comprehensive evidence-based medical evidence in the future.
Systematic Review Meta-Analysis Thyroid Nodule Xia Ku Cao
Successful intervention with Chinese herbal medicine for hyperthyroidism: Two case reports and a literature review
2021 Jul Explore: The Journal of Science & Healing Chia-Hui Lin, Chun-Pang Lin, Sheng-Teng Huang
As for the hyperthyroidism almost was controlled by Western medicine instead of CHM, we report that JWXYS as well as Prunella vulgaris, Fritillaria thunbergii, and Crassostrea gigas was a safe and effective formula and we propose that CHM may be considered as either a first choice or combination therapy to control hyperthyroidism.
Xia Ku Cao Mu Li Zhe Bei Mu Jia Wei Xiao Yao San Hyperthyroidism
Uncovering the pharmacological mechanism of the effects of the Banxia-Xiakucao Chinese Herb Pair on sleep disorder by a systems pharmacology approach
2020 Nov 24 Scientific Reports Guo J, Lou MP, Hu LL, Zhang X
BXHP contains a large number of bioactive compounds with different pharmacological properties. Additionally, the present study showed that the sedative-hypnotic effects of BXHP in patients with SD primarily operate via reductions in inflammation and the mediation of immune and CNS neurotransmitters that regulate multiple targets and pathways.
Network Pharmacology Insomnia Ban Xia Xia Ku CaoResearch insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.
Review Articles
Review articles summarise and critically evaluate the current state of research on a specific topic or field by synthesising multiple primary research studies.

Emerging therapeutic role of Prunella vulgaris in thyroid disease
2022 Jul Chinese Herbal Medicines Zhang W, Wuhan Q, Na M, Hu R, Mu Q, Bao X
Herbs such as P. vulgaris have great potential for treating thyroid disorders owing to their anti-oxidation and immunological effects and are frequently used as ingredients in herbal recipes. P. vulgaris is thought to combat drug toxicity within the body, therefore its own active ingredients have attracted much attention. The use of P. vulgaris with other drugs resulted in significant elimination of swollen nodules, reduced inflammatory response, and improved thyroid function. These effects of P. vulgaris benefit the clinical treatment of thyroid disease while having reduced drug-induced side effects and improved therapeutic effects. However, with only a few studies presenting treatment with Prunella vulgaris alone, further investigation is needed to to explore the physiological mechanisms.
Review Article Xia Ku Cao
Safety and efficacy of Prunella vulgaris preparation in adjuvant treatment of thyroid nodules
2021 Oct 15 Medicine Han Q, Xu N, Chen B, Wu W, Sheng L
PV combined with levothyroxine sodium tablets or thyroxin tablets has more benefits for thyroid nodules, further improving the clinical efficiency, reducing the diameter of nodules and reducing the occurrence of adverse reactions. However, the quality of these studies is uncertain, and higher quality and more RCTs are needed to provide comprehensive evidence-based medical evidence in the future.
Systematic Review Meta-Analysis Thyroid Nodule Xia Ku CaoClinical Trials
Clinical trials are research studies that involve people and are conducted to evaluate the safety and efficacy of new treatments or interventions, such as drugs, medical devices, or behavioural therapies.
Study Protocols
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