Heart Rate Variability
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Sleep quality in adults with disturbed sleep improved significantly after an 8-week course of naturally-derived sleep-inducing juice made from lettuce, orange, pineapple and cherry.
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Effects of Saffron Extract Supplementation on Mood, Well-Being, and Response to a Psychosocial Stressor in Healthy Adults: A Randomized, Double-Blind, Parallel Group, Clinical Trial
2021 Feb 01 Frontiers in Nutrition Jackson PA, Forster J, Khan J, Pouchieu C, Dubreuil S, Gaudout D, et al.
Experimental Study Randomised Controlled Trial SaffronSupplementation with standardized saffron extract improves depressive symptoms and social relationships in healthy individuals experiencing subclinical low mood and stress.
Effects of sleep-inducing juice on sleep quality and heart rate variability in adults with disturbed sleep
2020 Jan Nutrition Research and Practice Kim C, Kim M, Kim M, Jung H
Randomised Controlled Trial Sleep Heart Rate Variability Orange Pineapple LettuceSleep quality in adults with disturbed sleep improved significantly after an 8-week course of naturally-derived sleep-inducing juice made from lettuce, orange, pineapple and cherry.
Guasha improves the rating of perceived exertion scale score and reduces heart rate variability in male weightlifters: a randomized controlled trial
2017 Feb Journal of Traditional Chinese Medicine Xingze W, Peijie C, Xingyu H, Yingying W, Jinsheng Y, Eungpinichpong W, et al.
This article highlighted the efficacy of gua sha to facilitate the parasympathetic nervous activity and modulate the balance between parasympathetic and sympathetic activities in both the healthy men and the weightlifters.
Randomised Controlled TrialThe correlation between pulse diagnosis and constitution identification in traditional Chinese medicine
2017 Feb Complementary Therapies in Medicine Wu HK, Ko YS, Lin YS, Wu HT, Tsai TH, Chang HH
Individuals with qi-deficient and cold constitutions had higher AI and lower SEVI, potentially reflecting an increase in arterial stiffness. This study can provide a basis for further investigation of the physiological indicators of TCM constitutions in modern medicine.
Clinical Study Pulse diagnosisAcupuncture and heart rate variability: A systematic review
2010 Jun Autonomic Neuroscience: Basic and Clinical Lee S, Lee MS, Choi JY, Lee SW, Jeong SY, Ernst E
In conclusion, sham-controlled RCTs showed variable results and no clear evidence that acupuncture has any specific effects on heart rate variability (HRV).
Systematic Review Cardiovascular Disease Heart Rate VariabilityResearch Insights
Insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.
Supplementation with standardized saffron extract improves depressive symptoms and social relationships in healthy individuals experiencing subclinical low mood and stress.
2021 Frontiers in Nutrition Effects of Saffron Extract Supplementation on Mood, Well-Being, and Response to a Psychosocial Stressor in Healthy Adults: A Randomized, Double-Blind, Parallel Group, Clinical Trial Jackson PA, Forster J, Khan J, Pouchieu C, Dubreuil S, Gaudout D, et al.
Experimental Study Saffron
The study employed a double-blind, randomized, parallel groups design involving 56 healthy male and female participants aged between 18 and 54. They received either 30 mg standardized saffron extract or a placebo daily for 8 weeks. The saffron's chronic effects on subjective feelings of anxiety, stress, and depression were evaluated using a series of questionnaires. The acute effects of saffron following exposure to a lab-based psychosocial stressor were determined through assessing psychological and physiological parameters. As part of the process, the level of crocetin, a compound found in saffron, was quantified in the participants' urine.
The results indicated that individuals who received the saffron extract reported lower depression scores and improved social relationships after the 8-week period. A significant increase in urinary crocetin levels was observed with saffron supplementation, and these changes were found to be correlated with a decrease in depression scores. Additionally, the usual decrease in heart rate variability, a reaction commonly seen during the exposure to stressors, was found to be diminished after acute intake of saffron. The findings suggest that saffron extract can help improve subclinical depressive symptoms in healthy individuals and may increase resilience against the development of stress-related psychiatric disorders.
Sleep quality in adults with disturbed sleep improved significantly after an 8-week course of naturally-derived sleep-inducing juice made from lettuce, orange, pineapple and cherry.
2020 Nutrition Research and Practice Effects of sleep-inducing juice on sleep quality and heart rate variability in adults with disturbed sleep Kim C, Kim M, Kim M, Jung H
Randomised Controlled Trial Lettuce Orange Pineapple
This randomized, crossover study involved 25 adults (15 female, 10 male), all of whom reported difficulties in initiating or maintaining nighttime sleep. During the intervention, known as the feeding sessions (FS), the participants were given a sleep-inducing juice made of natural ingredients, being provided 250ml twice a day for 8 weeks. Their sleep quality and other related parameters were tracked with wearable actigraphs over seven consecutive days. The Pittsburgh sleep quality index (PSQI) scores were assessed before and after this juice intervention. The subjects' heart rate variability (HRV), both at rest and during sleep, was also closely monitored.
After the participants had undergone the 8-week juice intervention (FS), the PSQI scores decreased substantially, a change which directly correlated with a significant decrease in fatigue severity scale and visual analogue scale levels. Notably, heart rate variability indices indicative of vagal activity were significantly improved during the FS. The sleep efficiency and the total sleep time of the subjects increased significantly; at the same time, sleep latency and other disruptive factors like total counts, sleep fragmentation index, and movement index decreased significantly. There weren’t any significant differences observed during the non-feeding sessions (N-FS). Overall, the study results showed that the targeted intake of the sleep-inducing juice improved not only the sleep quality, but also led to an enhanced cardiac vagal tone during sleep.
Review Articles
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Clinical Trials
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Effects of Saffron Extract Supplementation on Mood, Well-Being, and Response to a Psychosocial Stressor in Healthy Adults: A Randomized, Double-Blind, Parallel Group, Clinical Trial
2021 Feb 01 Frontiers in Nutrition Jackson PA, Forster J, Khan J, Pouchieu C, Dubreuil S, Gaudout D, et al.
Experimental Study Randomised Controlled Trial SaffronSupplementation with standardized saffron extract improves depressive symptoms and social relationships in healthy individuals experiencing subclinical low mood and stress.
Effects of sleep-inducing juice on sleep quality and heart rate variability in adults with disturbed sleep
2020 Jan Nutrition Research and Practice Kim C, Kim M, Kim M, Jung H
Randomised Controlled Trial Sleep Heart Rate Variability Orange Pineapple LettuceSleep quality in adults with disturbed sleep improved significantly after an 8-week course of naturally-derived sleep-inducing juice made from lettuce, orange, pineapple and cherry.
Guasha improves the rating of perceived exertion scale score and reduces heart rate variability in male weightlifters: a randomized controlled trial
2017 Feb Journal of Traditional Chinese Medicine Xingze W, Peijie C, Xingyu H, Yingying W, Jinsheng Y, Eungpinichpong W, et al.
This article highlighted the efficacy of gua sha to facilitate the parasympathetic nervous activity and modulate the balance between parasympathetic and sympathetic activities in both the healthy men and the weightlifters.
Randomised Controlled TrialStudy Protocols
Published study protocols are detailed plans that outline the objectives, methodology, statistical analyses, and organisation of a research study that have been made publicly available for others to review and use as a reference.
Presentation Slides
Experimental Study
Supplementation with standardized saffron extract improves depressive symptoms and social relationships in healthy individuals experiencing subclinical low mood and stress.
Jackson PA, Forster J, Khan J, Pouchieu C, Dubreuil S, Gaudout D, Moras B, Pourtau L, Joffre F, Vaysse C, Bertrand K, Abrous H, Vauzour D, Brossaud J, Corcuff JB, Capuron L, Kennedy DO
Randomised Controlled Trial
Sleep quality in adults with disturbed sleep improved significantly after an 8-week course of naturally-derived sleep-inducing juice made from lettuce, orange, pineapple and cherry.
Kim C, Kim M, Kim M, Jung H
Executive Summary
Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Heart Rate Variability" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.
Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Heart Rate Variability" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.
Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Heart Rate Variability" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.
A Experimental Study published in 2021 in the journal Frontiers in Nutrition found that Supplementation with standardized saffron extract improves depressive symptoms and social relationships in healthy individuals experiencing subclinical low mood and stress. The study employed a double-blind, randomized, parallel groups design involving 56 healthy male and female participants aged between 18 and 54. They received either 30 mg standardized saffron extract or a placebo daily for 8 weeks. The saffron's chronic effects on subjective feelings of anxiety, stress, and depression were evaluated using a series of questionnaires. The acute effects of saffron following exposure to a lab-based psychosocial stressor were determined through assessing psychological and physiological parameters. As part of the process, the level of crocetin, a compound found in saffron, was quantified in the participants' urine. The results indicated that individuals who received the saffron extract reported lower depression scores and improved social relationships after the 8-week period. A significant increase in urinary crocetin levels was observed with saffron supplementation, and these changes were found to be correlated with a decrease in depression scores. Additionally, the usual decrease in heart rate variability, a reaction commonly seen during the exposure to stressors, was found to be diminished after acute intake of saffron. The findings suggest that saffron extract can help improve subclinical depressive symptoms in healthy individuals and may increase resilience against the development of stress-related psychiatric disorders.
A Randomised Controlled Trial published in 2020 in the journal Nutrition Research and Practice found that Sleep quality in adults with disturbed sleep improved significantly after an 8-week course of naturally-derived sleep-inducing juice made from lettuce, orange, pineapple and cherry. This randomized, crossover study involved 25 adults (15 female, 10 male), all of whom reported difficulties in initiating or maintaining nighttime sleep. During the intervention, known as the feeding sessions (FS), the participants were given a sleep-inducing juice made of natural ingredients, being provided 250ml twice a day for 8 weeks. Their sleep quality and other related parameters were tracked with wearable actigraphs over seven consecutive days. The Pittsburgh sleep quality index (PSQI) scores were assessed before and after this juice intervention. The subjects' heart rate variability (HRV), both at rest and during sleep, was also closely monitored. After the participants had undergone the 8-week juice intervention (FS), the PSQI scores decreased substantially, a change which directly correlated with a significant decrease in fatigue severity scale and visual analogue scale levels. Notably, heart rate variability indices indicative of vagal activity were significantly improved during the FS. The sleep efficiency and the total sleep time of the subjects increased significantly; at the same time, sleep latency and other disruptive factors like total counts, sleep fragmentation index, and movement index decreased significantly. There weren’t any significant differences observed during the non-feeding sessions (N-FS). Overall, the study results showed that the targeted intake of the sleep-inducing juice improved not only the sleep quality, but also led to an enhanced cardiac vagal tone during sleep.
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