Acyclovir

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Chinese Medicine Research Hub

Systematic Review

Long Dan Xie Gan Decoction combined with valacyclovir appears to enhance the treatment of herpes zoster, improving pain intensity, and crust formation time.

2021 Journal of Clinical Images and Medical Case Reports Efficacy and safety of Chinese herbal medicine longdanxiegan decoction combined with val-acyclovir in herpes zoster: A systematic review and mate-analysis
Wang X, , Wu L, Hou Y, Ding S, Wang S, Zhang Y, Zhang G, , , , , ,

Chinese Medicine Research Hub

Mung bean sprout extract has potent antiviral and to a lesser extent, prophylactic activities against both RSV and HSV-1, and in case of HSV-1, these activities were comparable to Acyclovir.

2015 BMC Complementary Medicine and Therapies Novel antiviral activity of mung bean sprouts against respiratory syncytial virus and herpes simplex virus −1: an in vitro study on virally infected Vero and MRC-5 cell lines
Hafidh, R.R., Abdulamir, A.S., Abu Bakar, F. et al.

Executive Summary

Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Acyclovir" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.

Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Acyclovir" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.

Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Acyclovir" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.

A Systematic Review published in 2021 in the journal Journal of Clinical Images and Medical Case Reports found that Long Dan Xie Gan Decoction combined with valacyclovir appears to enhance the treatment of herpes zoster, improving pain intensity, and crust formation time. For this systematic review, a comprehensive search was conducted in bibliographic databases - PubMed, Chinese Scientific Journals Database, China National Knowledge Infrastructure, and Wan-fang Database until the 6th of April, 2021. The main focus was on Randomised Controlled Trials (RCTs) that looked at herpes zoster treatments involving the combined use of Longdanxiegan Decoction (LDXGD) and valacyclovir. The quality of these studies was assessed using the Cochrane risk of bias tool and a meta-analysis was conducted using RevMan 5.4.1 software. The analysis incorporated five studies with a total of 414 participants. The methodological quality of these studies ranged from low to moderate. The combined use of LDXGD and valacyclovir showed relative benefits in efficacy rates compared to the use of valacyclovir alone. This was reflected in the lower pain intensity noted by a visual analogue scale, decreased incidence of postherpetic neuralgia (PHN), and shorter time frame to crust formation. However, the safety profile for the combined treatment of LDXGD and valacyclovir remains unclear.

A published in 2015 in the journal BMC Complementary Medicine and Therapies found that Mung bean sprout extract has potent antiviral and to a lesser extent, prophylactic activities against both RSV and HSV-1, and in case of HSV-1, these activities were comparable to Acyclovir. MBS extract has potent antiviral and to a lesser extent, prophylactic activities against both RSV and HSV-1, and in case of HSV-1, these activities were comparable to Acyclovir. Part of the underlying mechanism(s) of these activities is attributed to MBS potential to remarkably induce antiviral cytokines in human cells. Hence, we infer that MBS methanol extract could be used as such or as purified active component in protecting and treating RSV and HSV-1 infections. More studies are needed to pinpoint the exact active components responsible for the MBS antiviral activities.

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