Myelosuppression
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Research Articles
Published research studies are articles that present the findings of original research that has undergone a peer-review process and has been made publicly available in scholarly journals, books or other media.
Clinical Efficacy and Potential Mechanisms of Acupoint Stimulation Combined With Chemotherapy in Combating Cancer: A Review and Prospects
2022 Apr 25 Frontiers in Oncology Li S, Zhao S, Guo Y, Yang Y, Huang J, Wang J, et al.
In conclusion, the evidence suggests that acupoint stimulation can alleviate the side effects of chemotherapy and can also assist chemotherapeutic agents in inhibiting tumor growth, which expands the clinical application of acupoint stimulation in cancer treatment.
Review Article
The effect of acupuncture and selection of acupoints on myelosuppression after chemotherapy
2022 Jan TMR Non-Drug Therapy Wang XZ, Zhang XY, Zhang YN, Xia L
Acupuncture significantly inhibited the decline in blood cell components (white blood cell count, platelet count, red blood cell count, and hemoglobin) except for neutrophils in patients with myelosuppression after chemotherapy. Acupoints, mainly from the bladder meridian, stomach meridian, and spleen meridian, were distributed in the limbs and back. Specific points such as ST36 and SP6 were frequently used, with ST36-SP6-RN6-SP10-RN4 identified as a central combination in acupuncture prescriptions for this population.
Systematic Review Meta-Analysis Acupuncture MyelosuppressionZusanli (ST36) Acupoint Injection With Dexamethasone for Chemotherapy-Induced Myelosuppression: A Systematic Review and Meta-Analysis
2021 Jul 06 Frontiers in Oncology Chen J, Lin Z, Ding J
Systematic Review Meta-Analysis ST36ST36 acupoint injections with dexamethasone outperforms conventional western medicine in treating chemotherapy-induced myelosuppression, significantly improving clinical efficacy and recovery.
Chinese Herbal Medicine for Reducing Chemotherapy-Associated Side-Effects in Breast Cancer Patients: A Systematic Review and Meta-Analysis
2020 Dec 09 Frontiers in Oncology Li S, So T, Tang G, Tan HY, Wang N, Ng BFL, et al.
The included studies showed unsatisfied quality. Results based on available literature indicated that the adjunctive use of CHM with chemotherapy may reduce the chemotherapeutic agents-associated adverse events, including nausea and vomiting, diarrhea, alopecia, myelosuppression, and impaired immune function. A confident conclusion could not be have due to the lack of large scale and high quality trials.
Systematic Review Meta-AnalysisResearch Insights
Insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.
ST36 acupoint injections with dexamethasone outperforms conventional western medicine in treating chemotherapy-induced myelosuppression, significantly improving clinical efficacy and recovery.
2021 Frontiers in Oncology Zusanli (ST36) Acupoint Injection With Dexamethasone for Chemotherapy-Induced Myelosuppression: A Systematic Review and Meta-Analysis Chen J, Lin Z, Ding J
Systematic Review ST36
The study executed a systematic evaluation of the efficacy of ST36 acupoint injection with dexamethasone in treating chemotherapy-induced myelosuppression. A total of 17 randomized controlled trials from eight different databases were extracted for this meta-analysis. A detailed examination and analysis of various data gathered were performed using the Cochrane Collaboration tool for bias, Excel 2010 for creating an information extraction database, and RevMan 5.3.0 software for analyzing test data. The quality of evidence was graded using GRADE profiler 3.6 software.
The results indicated that compared to conventional western medicine, ST36 acupoint injection with dexamethasone vastly improved the clinical aggregate effective rate. Notably, it increased the white blood cell count and hemoglobin levels in patients, further enhancing their Karnofsky performance status. The treatment also shortened the recovery time of myelosuppression. However, there were no significant differences observed in platelet elevation between the ST36 acupoint injection with dexamethasone and conventional western medicine.
Review Articles
Review articles summarise and critically evaluate the current state of research on a specific topic or field by synthesising multiple primary research studies.
Clinical Efficacy and Potential Mechanisms of Acupoint Stimulation Combined With Chemotherapy in Combating Cancer: A Review and Prospects
2022 Apr 25 Frontiers in Oncology Li S, Zhao S, Guo Y, Yang Y, Huang J, Wang J, et al.
In conclusion, the evidence suggests that acupoint stimulation can alleviate the side effects of chemotherapy and can also assist chemotherapeutic agents in inhibiting tumor growth, which expands the clinical application of acupoint stimulation in cancer treatment.
Review ArticleThe effect of acupuncture and selection of acupoints on myelosuppression after chemotherapy
2022 Jan TMR Non-Drug Therapy Wang XZ, Zhang XY, Zhang YN, Xia L
Acupuncture significantly inhibited the decline in blood cell components (white blood cell count, platelet count, red blood cell count, and hemoglobin) except for neutrophils in patients with myelosuppression after chemotherapy. Acupoints, mainly from the bladder meridian, stomach meridian, and spleen meridian, were distributed in the limbs and back. Specific points such as ST36 and SP6 were frequently used, with ST36-SP6-RN6-SP10-RN4 identified as a central combination in acupuncture prescriptions for this population.
Systematic Review Meta-Analysis Acupuncture MyelosuppressionZusanli (ST36) Acupoint Injection With Dexamethasone for Chemotherapy-Induced Myelosuppression: A Systematic Review and Meta-Analysis
2021 Jul 06 Frontiers in Oncology Chen J, Lin Z, Ding J
Systematic Review Meta-Analysis ST36ST36 acupoint injections with dexamethasone outperforms conventional western medicine in treating chemotherapy-induced myelosuppression, significantly improving clinical efficacy and recovery.
Chinese Herbal Medicine for Reducing Chemotherapy-Associated Side-Effects in Breast Cancer Patients: A Systematic Review and Meta-Analysis
2020 Dec 09 Frontiers in Oncology Li S, So T, Tang G, Tan HY, Wang N, Ng BFL, et al.
The included studies showed unsatisfied quality. Results based on available literature indicated that the adjunctive use of CHM with chemotherapy may reduce the chemotherapeutic agents-associated adverse events, including nausea and vomiting, diarrhea, alopecia, myelosuppression, and impaired immune function. A confident conclusion could not be have due to the lack of large scale and high quality trials.
Systematic Review Meta-AnalysisPresentation Slides
ST36 acupoint injections with dexamethasone outperforms conventional western medicine in treating chemotherapy-induced myelosuppression, significantly improving clinical efficacy and recovery.
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