Cold & Hot Theory
Recent Insights
This review further put forward the possibility that cold-hot nature of food and Chinese medicine exert different biological effects on the inflammatory response via regulating the signaling pathways viz. NF-κB and MAPK.
Chinese Medicine Diet Therapy Cold & Hot Theory
ANOVA and multivariate analysis indicated that 18 food components have significant effects on cold/hot property of food and vitamins play an important role in food cold/hot properties.
Cold & Hot Theory
Based on the statistical analytic results, calories, dietary fiber, fat, retinol, and vitamin C were found to possibly determine the effect of Yin-Yang properties of foods on human health. The influence of these nutrients on the human body was partially consistent with the function of Yin, Yang and neutral foods recorded in traditional Chinese medicine.
Cold & Hot Theory
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Research Articles
Published research studies are articles that present the findings of original research that has undergone a peer-review process and has been made publicly available in scholarly journals, books or other media.
New insights into molecular mechanisms of "Cold or Hot" nature of food: When East meets West
2021 Apr 5 Food Research International Zhou Y, Xu B.
Cold & Hot Theory Chinese Medicine Diet TherapyThis review further put forward the possibility that cold-hot nature of food and Chinese medicine exert different biological effects on the inflammatory response via regulating the signaling pathways viz. NF-κB and MAPK.
A Song of Ice and Fire: Cold and Hot Properties of Traditional Chinese Medicines
2021 Jan 19 Frontiers in Pharmacology Liu J, Feng W, Peng C
Cold and hot properties of TCMs have played and will still play important roles in guiding TCM practitioners to combating human diseases. From ancient times to the present, people have been exploring the mystery of cold and hot properties of TCMs. In ancient times, the identification of cold and hot properties mainly depends on the healthy human’s direct feeling on a given TCM or the effects of TCMs on patients with cold or hot syndrome. Nowadays, some animal models (such as collagen-induced arthritis rats) and advanced technologies (such as network pharmacology) have been used to identify the cold and hot properties of TCMs. In recent years, phytochemical and pharmacologic research of cold and hot TCMs have indicated that although the chemical components are different, the representative cold TCMs all have antipyretic effects, and the typical hot TCMs all can promote thermogenesis. In addition, the studies on the mechanism related to the cold and hot properties have demonstrated that activating TRPM8 and inhibiting TRPV1 are the common mechanisms of the antipyretic effect of cold TCMs, and BAT activation and WAT browning are the common mechanisms of hot TCMs to promote thermogenesis. Although some progress has been made in understanding the cold and hot properties of TCMs, more and more studies are still needed to further explore the mechanism differences of TCMs with the same property.
Cold & Hot Theory Chinese Herbal MedicineRelationship between food composition and its cold/hot properties: A statistical study
2020 Dec Journal of Agriculture and Food Research A. Xie, H. Huang, F. Kong
Cold & Hot TheoryANOVA and multivariate analysis indicated that 18 food components have significant effects on cold/hot property of food and vitamins play an important role in food cold/hot properties.
The "active ingredients" of Yin, Yang and Neutral food and the effect of these nutrients on improving and maintaining health
2019 Dec 16 Scholar Works at UT Tyler Jingle Xu
Cold & Hot TheoryBased on the statistical analytic results, calories, dietary fiber, fat, retinol, and vitamin C were found to possibly determine the effect of Yin-Yang properties of foods on human health. The influence of these nutrients on the human body was partially consistent with the function of Yin, Yang and neutral foods recorded in traditional Chinese medicine.
Hot And Cold: An Old Theory With Modern Applications
2018 Jul Trends in Pharmaceutical Sciences Roodaki, Maryam & Abolhassanzadeh, Zohreh & Karimzadeh, Iman & Faridi, Pouya
The results show that there are some physiological and metabolic criteria, genes and networks and metabolite that contribute in determining the temperaments not only in body but also in disease, foods and drugs. Despite the presence of all these detailed data the lack of a comprehensive practical criteria for temperament is still obvious, so we try to gather all data to reach that in its best way.
Chinese Medicine Diet Therapy Cold & Hot TheoryResearch Insights
Insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.
This review further put forward the possibility that cold-hot nature of food and Chinese medicine exert different biological effects on the inflammatory response via regulating the signaling pathways viz. NF-κB and MAPK.
2021 Food Research International New insights into molecular mechanisms of "Cold or Hot" nature of food: When East meets West Zhou Y, Xu B.
Chinese Medicine Diet Therapy
This review explored that the cold and hot natures are not only linked to the chemical components such as water, carbohydrates, lipids, and amino acids, but also correlated to the biological effects, comprising of energy metabolism, inflammation response, oxidation reaction, immune response, and cell growth and proliferation. Besides, this review further put forward the possibility that cold-hot nature of food and Chinese medicine exert different biological effects on the inflammatory response via regulating the signaling pathways viz. NF-κB and MAPK. More extensive studies are needed to consider the overall connections between both the biological effects and chemical components and how food processing affects the cold-hot nature of the food.
ANOVA and multivariate analysis indicated that 18 food components have significant effects on cold/hot property of food and vitamins play an important role in food cold/hot properties.
2020 Journal of Agriculture and Food Research Relationship between food composition and its cold/hot properties: A statistical study A. Xie, H. Huang, F. Kong
The contents of 32 nutritional components and calorie were used through ANOVA and multivariate analysis to evaluate the most important variables affecting food warming and cooling characteristics, and the interaction effect of different components on food properties. Mathematical equations were derived to correlate the component variables and the probability of the food being cold/hot.
The results indicate vitamins (B6, folate, and VA) are among the most important influencing factors. Logit functions were developed to evaluate the hot and cold characteristics of a food based on its compositional data. The obtained information from this study is expected to enhance the understanding of the link between food composition and its cold/hot properties which may provide another method to evaluate the food diet and their health effect.
Based on the statistical analytic results, calories, dietary fiber, fat, retinol, and vitamin C were found to possibly determine the effect of Yin-Yang properties of foods on human health. The influence of these nutrients on the human body was partially consistent with the function of Yin, Yang and neutral foods recorded in traditional Chinese medicine.
2019 Scholar Works at UT Tyler The "active ingredients" of Yin, Yang and Neutral food and the effect of these nutrients on improving and maintaining health Jingle Xu
Having a healthy diet by restoring Yin-Yang balance is a cost-effective method to maintain overall health with positive effect on CVD, diabetes, gut microbiota, smoking therapy, sleep patterns, and some acute illnesses due to the determinant nutrients including fat, fiber, sodium, and vitamin C. While dietary fiber and sodium were not significant in this study. At a p<.10, fiber and sodium would have been significant. A Yin-Yang paradigm not only provides an alternative medicine intervention for patients by reducing economic burden, as well as improving symptoms and quality of life, but also is beneficial to healthy people by preventing disease. Yin-Yang balanced dietary therapy has a comprehensive effect on health and should be a significant component of health education.
Presentation Slides
This review further put forward the possibility that cold-hot nature of food and Chinese medicine exert different biological effects on the inflammatory response via regulating the signaling pathways viz. NF-κB and MAPK.
ANOVA and multivariate analysis indicated that 18 food components have significant effects on cold/hot property of food and vitamins play an important role in food cold/hot properties.
Based on the statistical analytic results, calories, dietary fiber, fat, retinol, and vitamin C were found to possibly determine the effect of Yin-Yang properties of foods on human health. The influence of these nutrients on the human body was partially consistent with the function of Yin, Yang and neutral foods recorded in traditional Chinese medicine.
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