Ma Huang

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Systematic Review

Ma Huang Tang may lower the duration of fever when it is used alone or in combination with neuraminidase inhibitors and may be a well-tolerated treatment.

2018 BMC Complementary Medicine and Therapies The use of maoto (Ma-Huang-Tang), a traditional Japanese Kampo medicine, to alleviate flu symptoms: a systematic review and meta-analysis
Yoshino, T., Arita, R., Horiba, Y. et al

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A Systematic Review published in 2018 in the journal BMC Complementary Medicine and Therapies found that Ma Huang Tang may lower the duration of fever when it is used alone or in combination with neuraminidase inhibitors and may be a well-tolerated treatment. Twelve relevant studies were identified, including two randomised controlled trials (RCTs, N = 60) and ten non-randomised studies (NRSs, N = 1110). We found that maoto plus NAIs was superior to NAIs alone in terms of the duration of fever in one RCT and four NRSs. The duration of symptoms or virus isolation did not differ between maoto and NAIs. No severe side effects or adverse reactions were reported related to maoto or NAIs. Although we could not reach a definitive conclusion because of the small sample sizes and high risk of bias in the analysed studies, maoto may lower the duration of fever when it is used alone or in combination with NAIs and may be a well-tolerated treatment. More RCTs are needed to determine the efficacy and safety of maoto.

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