Dang Gui Si Ni Decoction
Recent Insights
Related Topics
Research Articles
Published research studies are articles that present the findings of original research that has undergone a peer-review process and has been made publicly available in scholarly journals, books or other media.
Pharmacological Mechanism of Danggui-Sini Formula for Intervertebral Disc Degeneration: A Network Pharmacology Study
2021 Nov 11 BioMed Research International Wang L, Lin J, Li W
The study identified 119 active ingredients and 136 common genes, with 10 core genes (AKT1, IL6, ALB, TNF, VEGFA, TP53, MAPK3, CASP3, JUN, and EGF). Enrichment analysis revealed involvement in pathways such as the AGE-RAGE signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, apoptosis, cellular senescence, PI3K-Akt signaling pathway, and FoxO signaling pathway. Molecular docking confirmed stable affinity between core genes and key components, supporting the "multicomponent, multitarget, and multipathway" characteristics of DSF in IVDD treatment.
Network Pharmacology Dang Gui Si Ni Decoction
Comparative analysis of the compatibility effects of Danggui-Sini Decoction on a blood stasis syndrome rat model using untargeted metabolomics
2019 Jan Journal of Chromatography B Wu JX, Zheng H, Yao X, Liu XW, Zhu HJ, Yin CL, et al.
In this study, metabolic variations in rats with BSS and the intervention effect of DSD and its compatibility groups in BSS were investigated via UPLC-Q-TOF/MS based on untargeted metabolomics and multivariate statistical analysis. It demonstrated that metabolomics is a powerful tool for evaluating the efficacy and compatibility effects of traditional Chinese medicine (TCM).
Network Pharmacology Animal Study Blood Stasis Dang Gui Si Ni DecoctionStudy Protocols
Published study protocols are detailed plans that outline the objectives, methodology, statistical analyses, and organisation of a research study that have been made publicly available for others to review and use as a reference.
Sign In
Users not signed in are limited to viewing the 5 most recent items of content.