Atrial Fibrillation
Recent Insights
Adding Chinese herbal medicines to conventional therapy could decrease subsequent stroke risk for atrial fibrillation patients.
Atrial Fibrillation Stroke
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Research Articles
Published research studies are articles that present the findings of original research that has undergone a peer-review process and has been made publicly available in scholarly journals, books or other media.
An Overview of Systematic Reviews on the Effectiveness of Wenxin Keli in the Treatment of Atrial Fibrillation
2022 May 30 Evidence-Based Complementary and Alternative Medicine Wang Y, Liu Y, Yan X, Wang D
Wenxin Keli (WXKL) may be clinically efficacious and safe for the treatment of atrial fibrillation.
Systematic Review Huang Jing Wen Xin Ke Li
Investigating the efficiency and tolerability of traditional Chinese formulas combined with antiarrhythmic agents for paroxysmal atrial fibrillation: A systematic review and Bayesian network meta-analysis
2022 Jan Phytomedicine Jiang X, Luo Y, Wang X, Chen Y, Wang T, He J, et al.
Antiarrhythmic agents combined with traditional Chinese formulas had higher efficacy and lower toxicity than other treatment alternatives. This study might provide reference to help find the better treatment options for paroxysmal atrial fibrillation (PAF).
Systematic Review Meta-Analysis Atrial Fibrillation
Potential Mechanism of Dingji Fumai Decoction Against Atrial Fibrillation Based on Network Pharmacology, Molecular Docking, and Experimental Verification Integration Strategy
2021 Nov 11 Frontiers in Cardiovascular Medicine Liang Y, Liang B, Chen W, Wu XR, Liu-Huo WS, Zhao LZ
Dingji Fumai Decoction (DFD) could be utilized in treating AF through a complicated mechanism, including interactions between related active compounds and targets, promoting the explanation and understanding of the molecular biological mechanism of DFD in the treatment of atrial fibrillation (AF).
Network Pharmacology Atrial FibrillationReduced Stroke Risk among Patients with Atrial Fibrillation Receiving Chinese Herbal Medicines Treatment: Analysis of Domestic Data in Taiwan
2020 Jun 09 Medicina Zheng LC, Livneh H, Chen WJ, Lin MC, Lu MC, Yeh CC, et al.
Cohort Study Atrial Fibrillation StrokeAdding Chinese herbal medicines to conventional therapy could decrease subsequent stroke risk for atrial fibrillation patients.
Antiarrhythmic Mechanisms of Chinese Herbal Medicine Dingji Fumai Decoction
2020 Mar 20 Evidence-Based Complementary and Alternative Medicine Liang B, Zhou Y, Fu L, Liao HL
Dingji Fumai decoction (DFD) conclusively showed the mechanism of the class I antiarrhythmic properties and the safety profile. The discovery that DFD mitigates oxidative stress, alleviates the activation of Na+-K+-ATPase and Cx43, and blocks Nav1.5current shows the cellular electrophysiological mechanisms that support the clinical therapeutic effect of DFD.
Animal Study Dingji Fumai Decoction Atrial FibrillationResearch Insights
Insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.
Adding Chinese herbal medicines to conventional therapy could decrease subsequent stroke risk for atrial fibrillation patients.
2020 Medicina Reduced Stroke Risk among Patients with Atrial Fibrillation Receiving Chinese Herbal Medicines Treatment: Analysis of Domestic Data in Taiwan Zheng LC, Livneh H, Chen WJ, Lin MC, Lu MC, Yeh CC, et al.
Cohort Study Stroke
From a nationwide database, 11,456 AF patients aged ≧ 20 years between 1998 and 2007 were identified. Afterwards, we enrolled 2670 CHMs users and randomly selected 2670 non-CHMs users using the propensity score method. The occurrence of stroke was recorded until the end of 2012.
Within the follow-up period, 671 CHMs users and 900 non-CHMs users developed stroke, with incidence rates of 33.02 and 45.46 per 1000 person-years, respectively. CHMs use was associated with a 30% lower stroke risk, especially for those receiving CHMs for over two years.
Review Articles
Review articles summarise and critically evaluate the current state of research on a specific topic or field by synthesising multiple primary research studies.
An Overview of Systematic Reviews on the Effectiveness of Wenxin Keli in the Treatment of Atrial Fibrillation
2022 May 30 Evidence-Based Complementary and Alternative Medicine Wang Y, Liu Y, Yan X, Wang D
Wenxin Keli (WXKL) may be clinically efficacious and safe for the treatment of atrial fibrillation.
Systematic Review Huang Jing Wen Xin Ke LiInvestigating the efficiency and tolerability of traditional Chinese formulas combined with antiarrhythmic agents for paroxysmal atrial fibrillation: A systematic review and Bayesian network meta-analysis
2022 Jan Phytomedicine Jiang X, Luo Y, Wang X, Chen Y, Wang T, He J, et al.
Antiarrhythmic agents combined with traditional Chinese formulas had higher efficacy and lower toxicity than other treatment alternatives. This study might provide reference to help find the better treatment options for paroxysmal atrial fibrillation (PAF).
Systematic Review Meta-Analysis Atrial Fibrillation
Systematic Evaluation of Efficacy and Safety of Acupuncture Treatment for Patients with Atrial Fibrillation
2019 Jan 26 Open Access Macedonian Journal of Medical Sciences Fei Y, Fei R, Zhang J, Sun Y, Yu Q
Acupuncture has a good therapeutic effect and safety profile on patients with AF, and its application in clinical practice should be considered.
Systematic Review Meta-Analysis
Efficacy and safety of traditional Chinese medicine on thromboembolic events in patients with atrial fibrillation: A systematic review and meta-analysis
2017 Jun Complementary Therapies in Medicine Wang Z, Tang Z, Zhu W, Ge L, Ge J
This meta-analysis suggests that TCM combined with warfarin is superior to warfarin alone for the prevention of total thromboembolic events in patients with AF, with equal risk of bleeding as warfarin alone.
Systematic Review Meta-Analysis WarfarinApplication of Traditional Chinese Medicine in Treatment of Atrial Fibrillation
2017 Jan Evidence-Based Complementary and Alternative Medicine Dong Y, Liao J, Yao K, Jiang W, Wang J
In conclusion, despite suffering from lack of adequate mechanistic and clinical studies, TCM research in this area is exciting and may lead to the development of new drugs just like the discovery of amiodarone which is extracted from a plant named Ammi visnaga.
Review ArticleStudy Protocols
Published study protocols are detailed plans that outline the objectives, methodology, statistical analyses, and organisation of a research study that have been made publicly available for others to review and use as a reference.
Presentation Slides
Adding Chinese herbal medicines to conventional therapy could decrease subsequent stroke risk for atrial fibrillation patients.
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