Review Articles
Review articles summarise and critically evaluate the current state of research on a specific topic or field by synthesising multiple primary research studies.
Study Protocols
Published study protocols are detailed plans that outline the objectives, methodology, statistical analyses, and organisation of a research study that have been made publicly available for others to review and use as a reference.
Presentation Slides
Chinese Medicine Research Hub
Experimental Study
Moderate consumption of blueberries may effectively reduce bone loss in healthy postmenopausal women.
2023 The American Journal of Clinical Nutrition Moderate consumption of freeze-dried blueberry powder increased net bone calcium retention compared with no treatment in healthy postmenopausal women: a randomized crossover trial
Hodges JK, Maiz M, Cao S, Lachcik PJ, Peacock M, McCabe GP, McCabe LD, Cladis DP, Jackson GS, Ferruzzi MG, Lila MA, Bailey RL, Martin BR, Weaver CM
Chinese Medicine Research Hub
Animal Study
Pomegranate extracts enhance bone formation and increase bone calcium content in mice.
2011 British Journal of Nutrition Effects of pomegranate extracts on cartilage, bone and mesenchymal cells of mouse fetuses
Monsefi M, Parvin F, Talaei-Khozani T
Executive Summary
Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Bone Calcium" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.
Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Bone Calcium" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.
Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Bone Calcium" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.
A Experimental Study published in 2023 in the journal The American Journal of Clinical Nutrition found that Moderate consumption of blueberries may effectively reduce bone loss in healthy postmenopausal women. The research began with a blueberry dose-response study with ovariectomized rats, used as an experimental model simulating postmenopausal conditions. These rats were fed with various doses of blueberry powder, with the aim to identify an optimal dosage for bone calcium retention. The experiment then translated to a human study where fourteen healthy women, all more than four years past menopause, were examined. A baseline was established, and then each participant was provided with varying dosages of freeze-dried blueberry powder equivalent to defined portions of fresh blueberries, to be consumed daily for a series of six weeks at a time. Tracing calcium in the urine was employed as a method to monitor bone calcium balances in both the rat and human trials.
The collected data indicated that both the rat and human subjects benefited from blueberry interventions at lower doses. Higher doses, however, showed no such beneficial impact on bone calcium balance. In human subjects, net bone calcium retention increased with low and medium doses of blueberry consumption. Increased urinary excretion of hippuric acid, a metabolite of the antioxidants present in blueberries, was observed with an increase in blueberry consumption. No significant associations were found between bone resorption biomarkers and the interventions implemented in the study.
A Animal Study published in 2011 in the journal British Journal of Nutrition found that Pomegranate extracts enhance bone formation and increase bone calcium content in mice. In this research, fifty pregnant Balb/c mice were administered with either a vehicle, pomegranate juice extract (PJE), pomegranate husk extract (PHE), or a mixture of husk and juice extract (PME). On the 19th day of gestation, the embryos were stained to measure femur and tibia lengths and their ossification zones; the bone calcium content in the pregnant mice was also assessed. Apart from that, cells from fetal limb buds were cultured and exposed to various concentrations of PJE, PHE, or PME to study their impacts on cell proliferation and differentiation.
The findings from the study suggest the beneficial impact of pomegranate extracts on bone health. Mice treated with Pomegranate Juice Extract showed an increase in bone calcium content, a crucial component of bone health. Furthermore, dietary supplementation with all types of extracts resulted in significant enhancements in embryo femur length and the osteogenesis index, indicating improved bone formation. The cellular studies also revealed a greater number of viable cells, more cartilage nodules, and increased diameters when exposed to the extracts, suggesting enhanced cell proliferation and differentiation rates and thus promoting bone development.
