Cranberry

Presentation Slides

Chinese Medicine Research Hub

Review Article

Berry fruits such as blueberries, cranberries, raspberries, and strawberries could potentially improve gut microbiota and reverse dysbiosis in chronic kidney disease patients.

2023 Nutrition Reviews Blueberry, cranberry, raspberry, and strawberry as modulators of the gut microbiota: target for treatment of gut dysbiosis in chronic kidney disease? From current evidence to future possibilities
Coutinho-Wolino KS, Melo MFS, Mota JC, Mafra D, Guimarães JT, Stockler-Pinto MB

Chinese Medicine Research Hub

Meta-Analysis

Blueberry and cranberry consumption significantly lowered fasting blood glucose and glycated hemoglobin levels in individuals with diabetes.

2022 Nutrition, Metabolism and Cardiovascular Diseases Effects of blueberry and cranberry on type 2 diabetes parameters in individuals with or without diabetes: A systematic review and meta-analysis of randomized clinical trials
Delpino FM, Figueiredo LM, Gonçalves da Silva T, Flores TR

Chinese Medicine Research Hub

Meta-Analysis

Chronic consumption of cranberry or cherry juice might considerably improve blood pressure levels.

2020 European Journal of Nutrition Effects of chronic consumption of specific fruit (berries, citrus and cherries) on CVD risk factors: a systematic review and meta-analysis of randomised controlled trials
Wang Y, Gallegos JL, Haskell-Ramsay C, Lodge JK

Executive Summary

Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Cranberry" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.

Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Cranberry" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.

Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Cranberry" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.

A Review Article published in 2023 in the journal Nutrition Reviews found that Berry fruits such as blueberries, cranberries, raspberries, and strawberries could potentially improve gut microbiota and reverse dysbiosis in chronic kidney disease patients. Methodology: This research explores the therapeutic potential of berry fruits, including blueberries, cranberries, raspberries, and strawberries, in relation to modulating gut microbiota in chronic kidney disease (CKD) patients. The fruit’s rich polyphenol and nutrient content are assumed to promote the selective growth of beneficial bacteria, thus improving the clinical status of these patients. The study scrutinizes the impact on the abundance of mucus-producing bacteria and short-chain fatty acids specifically. Discussion of Results: The gathered evidence illustrates that berry fruits, particularly with a daily intake of 5 mg, can promote diversity in the gut microbiota and possibly reverse dysbiosis, a common issue in chronic kidney disease patients. These fruits are found to increase the expression of mRNA involved in gut tight junctions such as occludin, TJP1, and mucin, and they may reduce uremic toxins by controlling the gut microbiota, improving the uremic condition. As such, long-term use of berry fruits could be an effective strategy for CKD patients.

A Meta-Analysis published in 2022 in the journal Nutrition, Metabolism and Cardiovascular Diseases found that Blueberry and cranberry consumption significantly lowered fasting blood glucose and glycated hemoglobin levels in individuals with diabetes. The research methodology involved a systematic literature review and meta-analysis using publications sourced from seven different databases (PubMed, LILACS, Scielo, Scopus, Web of Science, Cochrane, and Embase) up until May 2021. The researchers included randomized clinical trials where the effects of blueberry or cranberry on parameters linked to type 2 diabetes such as fasting blood glucose, insulin resistance, and glycated hemoglobin were compared. The quality of these studies was evaluated using the Cochrane scale while the Egger test was utilized to assess publication bias and the meta-regression evaluated the estimated effect sizes with potential moderator variables. Following an initial identification of 2034 studies, 39 full-text studies were read, out of which 22 met the criteria to be included in the final meta-analysis. The findings showed that individuals with diabetes experienced significant reductions in fasting blood glucose and glycated hemoglobin readings following the consumption of blueberries or cranberries. However, no significant effects were seen on insulin resistance. While the results were not universally significant when it came to the general population, an exception was found in the sensitivity analysis for fasting blood glucose.

A Meta-Analysis published in 2020 in the journal European Journal of Nutrition found that Chronic consumption of cranberry or cherry juice might considerably improve blood pressure levels. The review involved a comprehensive search across several databases including PubMed, Web of Science, Scopus, and psycARTICLES from the beginning until January 2020. The search results included forty-five randomized controlled trials that lasted at least a week, assessing the effects of berries, citrus, and cherries on different cardiovascular disease risk indicators. These indicators were endothelial function, blood pressure, lipid status, and inflammatory biomarkers. Different preparations of berries including juice of barberry, cranberry, grape, pomegranate, blueberry powder, grape, raspberry and freeze-dried strawberry were studied. The resulting reports showed improvements in endothelial function, inflammation markers, lipid status, and blood pressure. Among the interventions, cranberry juice and cherry juice were notably associated with a potential decrease in systolic and diastolic blood pressure. Consumption of berries led to a significant increase in the levels of sVCAM-1, a protein that is usually found higher in people with cardiovascular risk. However, no significant improvements were observed for other specified fruits in this research.

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