Glycaemic Control

Presentation Slides

Chinese Medicine Research Hub

Randomised Controlled Trial

Consumption of unripe avocado extract in the diet may lower postprandial insulin levels in overweight adults with previously elevated insulin levels.

2023 Nutrients Effects of an Unripe Avocado Extract on Glycaemic Control in Individuals with Obesity: A Double-Blinded, Parallel, Randomised Clinical Trial
Zhao L, Ingram DK, Gumpricht E, De Paoli T, Teong XT, Liu B, Mori TA, Heilbronn LK, Roth GS

Chinese Medicine Research Hub

Systematic Review

Consuming walnuts does not significantly alter blood glucose levels, indicating cardiovascular protective effects of walnuts are not due to improved glycaemic control.

2020 British Journal of Nutrition Effect of walnut consumption on markers of blood glucose control: a systematic review and meta-analysis
Neale, E., Guan, V., Tapsell, L., & Probst, Y.

Executive Summary

Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Glycaemic Control" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.

Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Glycaemic Control" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.

Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Glycaemic Control" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.

A Randomised Controlled Trial published in 2023 in the journal Nutrients found that Consumption of unripe avocado extract in the diet may lower postprandial insulin levels in overweight adults with previously elevated insulin levels. In this study, a double-blinded, randomised controlled trial was performed on 60 non-diabetic adults (with a majority of 47 being women, average age 48 years, BMI 34.0 kg/m). The participants were stratified by sex and randomised into two groups. One group daily consumed an extract from unripe avocado (10 g finely ground, freeze-dried unripe avocado), while the other took a placebo (10 g finely ground cornmeal supplemented with 5% spinach powder) over a period of 12 weeks. The primary outcome measured was the change in glucose area under the curve (AUC) in response to a 75 g oral glucose tolerance test. The results showed no significant differences between both groups in terms of glucose AUC, insulin AUC, or cardiovascular outcomes. However, in a subgroup analysis focusing on participants with above median baseline postprandial insulin levels, there was a notable reduction in insulin AUC in those who consumed the avocado extract compared to the placebo. This suggests that the daily consumption of an unripe avocado extract, enriched in MH, might not significantly impact glucose tolerance or insulin sensitivity in obese non-diabetic adults. Nonetheless, there seems to be a potential benefit of this intervention on postprandial insulin levels in individuals with initially elevated insulin responses.

A Systematic Review published in 2020 in the journal British Journal of Nutrition found that Consuming walnuts does not significantly alter blood glucose levels, indicating cardiovascular protective effects of walnuts are not due to improved glycaemic control. The study involved a systematic review and meta-analysis of previous randomized trials that investigated the effects of walnut consumption on glycaemic control markers such as fasting blood glucose, insulin, and glycated Hb. Studies were found through a comprehensive search of databases including Medline, PubMed, CINAHL, and Cochrane up to March 2nd, 2019. The included studies' risk of bias was assessed using the Cochrane Risk of Bias tool. In light of the results, although 16 studies were included in the review, it was found that walnut consumption did not significantly impact fasting blood glucose levels or other markers for glycaemic control. Recognizing that the studies included in the analysis were either deemed to have 'some concerns' or 'high risk' of bias, these results suggest that the beneficial effects of walnuts on cardiovascular health aren't caused by improvements in glycaemic control.

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