Histamine
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Published research studies are articles that present the findings of original research that has undergone a peer-review process and has been made publicly available in scholarly journals, books or other media.

Cupping therapy for patients with chronic urticaria: A systematic review and meta-analysis
2020 Jul Journal of Integrative Medicine Xiao, X., Zhang, L., Shi, Y., et al.
Systematic Review Meta-Analysis Hives Cupping Skin ConditionsCupping therapy, as an adjunct to current treatments, may potentially enhance efficacy when treating patients with chronic urticaria.

Characterization of cAMP as an anti-allergic functional factor in Chinese jujube (Ziziphus jujuba Mill.)
2019 Sep Journal of Functional Foods Jiang T, He F, Han S, Chen C, Zhang Y, Che H
IgE Histamine Hay Fever cAMP JujubeThis article was submitted by Jinnan C. and is awaiting moderation..

Impact of acupuncture on antihistamine use in patients suffering seasonal allergic rhinitis: secondary analysis of results from a randomised controlled trial
2018 Jun Acupuncture in Medicine Adam D, Grabenhenrich L, Ortiz M, Binting S, Reinhold T, Brinkhaus B
Randomised Controlled TrialAcupuncture appeared to significantly reduce the number of days of antihistamine use while improving rhinitis-specific quality of life and seasonal allergic rhinitis symptoms
Research insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.

2020 Journal of Integrative Medicine
Cupping therapy, as an adjunct to current treatments, may potentially enhance efficacy when treating patients with chronic urticaria.
Systematic Review Cupping Hives Skin Conditions
Cupping therapy for patients with chronic urticaria: A systematic review and meta-analysis
Xiao, X., Zhang, L., Shi, Y., et al.

2018 Acupuncture in Medicine
Acupuncture appeared to significantly reduce the number of days of antihistamine use while improving rhinitis-specific quality of life and seasonal allergic rhinitis symptoms
Randomised Controlled Trial
Impact of acupuncture on antihistamine use in patients suffering seasonal allergic rhinitis: secondary analysis of results from a randomised controlled trial
Adam D, Grabenhenrich L, Ortiz M, Binting S, Reinhold T, Brinkhaus B
Review Articles
Review articles summarise and critically evaluate the current state of research on a specific topic or field by synthesising multiple primary research studies.
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Clinical trials are research studies that involve people and are conducted to evaluate the safety and efficacy of new treatments or interventions, such as drugs, medical devices, or behavioural therapies.
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Published study protocols are detailed plans that outline the objectives, methodology, statistical analyses, and organisation of a research study that have been made publicly available for others to review and use as a reference.
Presentation Slides

Systematic Review
Cupping therapy, as an adjunct to current treatments, may potentially enhance efficacy when treating patients with chronic urticaria.
Xiao, X., Zhang, L., Shi, Y., Yao, J., Cao, W., Liu, Y., Zou, Z., Zhou, S., Chen, M., Li, C., Zheng, Q., & Li, Y.

Randomised Controlled Trial
Acupuncture appeared to significantly reduce the number of days of antihistamine use while improving rhinitis-specific quality of life and seasonal allergic rhinitis symptoms
Adam D, Grabenhenrich L, Ortiz M, Binting S, Reinhold T, Brinkhaus B
Executive Summary
Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Histamine" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.
Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Histamine" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.
Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Histamine" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.
A Systematic Review published in 2020 in the journal Journal of Integrative Medicine found that Cupping therapy, as an adjunct to current treatments, may potentially enhance efficacy when treating patients with chronic urticaria. The research adopted a systematic review of randomized controlled trials, with the focus on efficacy and safety of cupping therapy for chronic urticaria. The researchers employed a search strategy aimed at identifying related keywords like "chronic urticaria" and "cupping therapy" in the title and abstracts, sourced from nine major electronic databases up till May 2019. Only trials that included patients with chronic urticaria who received dry or wet cupping were considered. The quality of the methodological design and potential bias of the studies were evaluated. The findings suggest the efficacy of cupping therapy when used, not as a standalone treatment, but as an adjunct to other treatments, particularly to antihistamines and acupuncture. In a sample of trials, there were no significant differences between using wet cupping and conventional medications in terms of their total effective rate. However, cupping therapy combined with antihistamines or acupuncture was found to be more effective than when these treatments were used separately. No serious adverse events were reported as part of these findings.
A Randomised Controlled Trial published in 2018 in the journal Acupuncture in Medicine found that Acupuncture appeared to significantly reduce the number of days of antihistamine use while improving rhinitis-specific quality of life and seasonal allergic rhinitis symptoms The data from 414 patients were analysed. The acupuncture group used antihistamines significantly less often compared with the other groups (acupuncture vs sham acupuncture: mean difference −4.49 days, p=0.01; acupuncture vs RM: mean difference −9.15 days, p<0.001). Approximately 38% of the acupuncture group did not use any antihistamine in contrast to only 16% in the RM group. The pre-post comparison suggested that the acupuncture patients did not need to increase the days of antihistamine use to alleviate their symptoms, unlike the other groups. Acupuncture appeared to significantly reduce the number of days of antihistamine use while improving RQoL and SAR symptoms; it can therefore be considered a valuable, additional treatment option for patients with SAR.
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