Lettuce
Recent Insights
Soybean lettuce extract effectively reduces symptoms of menopause syndrome without notable side effects.
Lettuce Menopause Soybean
Sleep quality in adults with disturbed sleep improved significantly after an 8-week course of naturally-derived sleep-inducing juice made from lettuce, orange, pineapple and cherry.
Heart Rate Variability Lettuce Orange
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Research Articles
Published research studies are articles that present the findings of original research that has undergone a peer-review process and has been made publicly available in scholarly journals, books or other media.
Evaluation of the Effectiveness of Fermented Soybean-Lettuce Powder for Improving Menopausal Symptoms
2022 Jul 13 Nutrients Han AL, Lee HK, Chon HS, Pae HO, Kim MS, Shin YI, et al.
Randomised Controlled Trial Menopause Lettuce SoybeanSoybean lettuce extract effectively reduces symptoms of menopause syndrome without notable side effects.
Effects of sleep-inducing juice on sleep quality and heart rate variability in adults with disturbed sleep
2020 Jan Nutrition Research and Practice Kim C, Kim M, Kim M, Jung H
Randomised Controlled Trial Sleep Heart Rate Variability Orange Pineapple LettuceSleep quality in adults with disturbed sleep improved significantly after an 8-week course of naturally-derived sleep-inducing juice made from lettuce, orange, pineapple and cherry.
Research Insights
Insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.
Soybean lettuce extract effectively reduces symptoms of menopause syndrome without notable side effects.
2022 Nutrients Evaluation of the Effectiveness of Fermented Soybean-Lettuce Powder for Improving Menopausal Symptoms Han AL, Lee HK, Chon HS, Pae HO, Kim MS, Shin YI, et al.
Randomised Controlled Trial Menopause Soybean
The study targeted adult women suffering from menopausal syndrome with a Kupperman index of 15 or more. Participants were split into two groups – the experimental group and the placebo group. The research spanned over a four-week period and embraced a total of 39 participants (with one dropping out). Measurements of body mass index, waist circumference, and several cholesterol levels were taken before and after the study, but these didn't show any significant changes.
In the results discussion, the most notable finding was a significant reduction in the Kupperman index in the experimental group. They were given the natural nitric oxide-containing soybean lettuce extract. This decrease denotes the alleviation of menopausal symptoms, offering an effective, natural alternative to hormone therapy. Conversely, the placebo group didn't show any substantial change, reinforcing the efficacy of the soybean lettuce extract.
Sleep quality in adults with disturbed sleep improved significantly after an 8-week course of naturally-derived sleep-inducing juice made from lettuce, orange, pineapple and cherry.
2020 Nutrition Research and Practice Effects of sleep-inducing juice on sleep quality and heart rate variability in adults with disturbed sleep Kim C, Kim M, Kim M, Jung H
Randomised Controlled Trial Heart Rate Variability Orange Pineapple
This randomized, crossover study involved 25 adults (15 female, 10 male), all of whom reported difficulties in initiating or maintaining nighttime sleep. During the intervention, known as the feeding sessions (FS), the participants were given a sleep-inducing juice made of natural ingredients, being provided 250ml twice a day for 8 weeks. Their sleep quality and other related parameters were tracked with wearable actigraphs over seven consecutive days. The Pittsburgh sleep quality index (PSQI) scores were assessed before and after this juice intervention. The subjects' heart rate variability (HRV), both at rest and during sleep, was also closely monitored.
After the participants had undergone the 8-week juice intervention (FS), the PSQI scores decreased substantially, a change which directly correlated with a significant decrease in fatigue severity scale and visual analogue scale levels. Notably, heart rate variability indices indicative of vagal activity were significantly improved during the FS. The sleep efficiency and the total sleep time of the subjects increased significantly; at the same time, sleep latency and other disruptive factors like total counts, sleep fragmentation index, and movement index decreased significantly. There weren’t any significant differences observed during the non-feeding sessions (N-FS). Overall, the study results showed that the targeted intake of the sleep-inducing juice improved not only the sleep quality, but also led to an enhanced cardiac vagal tone during sleep.
Clinical Trials
Clinical trials are research studies that involve people and are conducted to evaluate the safety and efficacy of new treatments or interventions, such as drugs, medical devices, or behavioural therapies.
Evaluation of the Effectiveness of Fermented Soybean-Lettuce Powder for Improving Menopausal Symptoms
2022 Jul 13 Nutrients Han AL, Lee HK, Chon HS, Pae HO, Kim MS, Shin YI, et al.
Randomised Controlled Trial Menopause Lettuce SoybeanSoybean lettuce extract effectively reduces symptoms of menopause syndrome without notable side effects.
Effects of sleep-inducing juice on sleep quality and heart rate variability in adults with disturbed sleep
2020 Jan Nutrition Research and Practice Kim C, Kim M, Kim M, Jung H
Randomised Controlled Trial Sleep Heart Rate Variability Orange Pineapple LettuceSleep quality in adults with disturbed sleep improved significantly after an 8-week course of naturally-derived sleep-inducing juice made from lettuce, orange, pineapple and cherry.
Presentation Slides
Soybean lettuce extract effectively reduces symptoms of menopause syndrome without notable side effects.
Sleep quality in adults with disturbed sleep improved significantly after an 8-week course of naturally-derived sleep-inducing juice made from lettuce, orange, pineapple and cherry.
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