Sleep Disorder
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Research Articles
Published research studies are articles that present the findings of original research that has undergone a peer-review process and has been made publicly available in scholarly journals, books or other media.
Electro-acupuncture on Vascular Parkinsonism with multiple sleep disorders: A Case Report
2022 Dec 19 Frontiers in Neurology Yan M, Fan J, Li Y, Liu X, Yu Z, Zhuang L
After 8 weeks of EA treatment, the patient reported that the symptoms of subjective and objective sleep disturbance were significantly alleviated without any discomfort. This case report may provide a new alternative and complementary therapy for VP patients with sleep disturbance but more definitive and robust evidence is needed to support its efficacy.
Case Report
Effects of Green Kiwifruit Peel Extract on Sleep-Wake Profiles in Mice: A Polysomnographic Study Based on Electroencephalogram and Electromyogram Recordings
2022 Nov 09 Nutrients Kim D, Yoon M, Kim S, Um MY, Cho S
Experimental Study Animal Study KiwifruitThe ethanol extract from green kiwifruit peel enhances sleep duration and onset, proving to be a potential natural aid for treating sleep disorders.
The potential for traditional Chinese therapy in treating sleep disorders caused by COVID-19 through the cholinergic anti-inflammatory pathway
2022 Oct 10 Frontiers in Pharmacology Xie X, Zhang N, Fu J, Wang Z, Ye Z, Liu Z
The reasons for the sleep disorders caused by the novel coronavirus and found that inflammation was the main reason leading to sleep distress in patients. And we reviewed the mechanisms of three common traditional Chinese in inhibiting inflammation through CAP and relieving the sleep or symptoms. We, therefore, propose that TCT may be a potential strategy to take for the treatment of sleep problems due to inflammation caused by COVID-19.
Review Article
Traditional Chinese Medicine for Post-stroke Sleep Disorders: The Evidence Mapping of Clinical Studies
2022 Jun 15 Frontiers in Psychiatry Su Q, Zou D, Gai N, Li H, Kuang Z, Ni X
Post-stroke sleep disorders (PSSDs) treated with traditional Chinese medicine (TCM) have been widely assessed in clinical studies.
Systematic Review
Acupuncture in the Treatment of Parkinson’s Disease with Sleep Disorders and Dose Response
2022 Feb 23 BioMed Research International Li L, Jin X, Cong W, Du T, Zhang W
The sleep condition of Parkinson’s disease sleep disorders (PDSD) patients can be improved by acupuncture, which can effectively relieve sleep quality, can also be shown by ActiGraph, and shows a dose-response relationship.
Clinical StudyResearch Insights
Insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.
The ethanol extract from green kiwifruit peel enhances sleep duration and onset, proving to be a potential natural aid for treating sleep disorders.
2022 Nutrients Effects of Green Kiwifruit Peel Extract on Sleep-Wake Profiles in Mice: A Polysomnographic Study Based on Electroencephalogram and Electromyogram Recordings Kim D, Yoon M, Kim S, Um MY, Cho S
Experimental Study Kiwifruit
The study employed the electroencephalogram (EEG) and electromyogram analysis methodologies in mice to investigate the sleep-promoting effects of the kiwifruit peel extract. Each participant mouse was administered with varying doses (250, 500, and 1000 mg/kg) of green kiwifruit peel ethanol extract (GKPEE) and their sleep duration, latency and onset were consistently observed and recorded. For comparison purposes, results were weighed against similar analyses conducted using diazepam, a traditional sedative-hypnotic drug.
In terms of results, the findings indicated that acute administration of GKPEE significantly increased non-rapid eye movement sleep and decreased sleep latency, in a dose-dependent relationship. Moreover, the effects did not alter delta activity, differing significantly from diazepam outcomes. Notably, these effects prevailed even with sub-chronic administration over 15 days, with the EEG power density not revealing any noteworthy differences - an indicator of the absence of a tolerance phenomenon. Additionally, these results suggest an alternative usage of kiwifruit by-products from the food industry, providing possible environmental benefits.
Acupuncture can be safely applied as an alternative, adjuvant treatment in clinical practice to treat sleep disorders in postmenopausal women.
2015 Evidence-Based Complementary and Alternative Medicine Acupuncture to Treat Sleep Disorders in Postmenopausal Women: A Systematic Review Bezerra AG, Pires GN, Andersen ML, Tufik S, Hachul H.
Systematic Review
In general, these studies presented improvements in sleep-related variables. Despite the overall positive effects, acupuncture still cannot be stated as a reliable treatment for sleep-related complaints, not due to inefficacy, but rather limited evidence. Nevertheless, results are promising and new comprehensive and controlled studies in the field are encouraged.
Regardless of the still limited evidence about the effects of acupuncture for postmenopausal sleep disorders, none of the selected articles described side or deleterious effects. Thus, acupuncture can be safely applied in clinical practice for this population as an alternative treatment, but not as primary or single conduct.
Review Articles
Review articles summarise and critically evaluate the current state of research on a specific topic or field by synthesising multiple primary research studies.
The potential for traditional Chinese therapy in treating sleep disorders caused by COVID-19 through the cholinergic anti-inflammatory pathway
2022 Oct 10 Frontiers in Pharmacology Xie X, Zhang N, Fu J, Wang Z, Ye Z, Liu Z
The reasons for the sleep disorders caused by the novel coronavirus and found that inflammation was the main reason leading to sleep distress in patients. And we reviewed the mechanisms of three common traditional Chinese in inhibiting inflammation through CAP and relieving the sleep or symptoms. We, therefore, propose that TCT may be a potential strategy to take for the treatment of sleep problems due to inflammation caused by COVID-19.
Review ArticleTraditional Chinese Medicine for Post-stroke Sleep Disorders: The Evidence Mapping of Clinical Studies
2022 Jun 15 Frontiers in Psychiatry Su Q, Zou D, Gai N, Li H, Kuang Z, Ni X
Post-stroke sleep disorders (PSSDs) treated with traditional Chinese medicine (TCM) have been widely assessed in clinical studies.
Systematic ReviewAcupuncture to Treat Sleep Disorders in Postmenopausal Women: A Systematic Review
2015 Aug 23 Evidence-Based Complementary and Alternative Medicine Bezerra AG, Pires GN, Andersen ML, Tufik S, Hachul H.
Systematic ReviewAcupuncture can be safely applied as an alternative, adjuvant treatment in clinical practice to treat sleep disorders in postmenopausal women.
Clinical Trials
Clinical trials are research studies that involve people and are conducted to evaluate the safety and efficacy of new treatments or interventions, such as drugs, medical devices, or behavioural therapies.
Scalp acupuncture for sleep disorder induced by pre-examination anxiety in undergraduates
2018 Sep World Journal of Acupuncture-Moxibustion DONG G, CAO D, DONG Y, ZHANG J, WANG F
Both scalp acupuncture and traditional acupuncture therapies are effective on sleep disorder induced by pre-examination anxiety in the undergraduates. The scalp acupuncture therapy achieves the better effects on the instant relief of symptoms.
Randomised Controlled Trial
Acupuncture as Adjuvant Therapy for Sleep Disorders in Parkinson’s Disease
2017 Feb Journal of Acupuncture and Meridian Studies Aroxa FHA, Gondim ITGO, Santos ELW, Coriolano MGWS, Asano AGC, Asano NMJ
This study presented a potential therapeutic benefit of acupuncture on sleep disturbs of Parkinson's disease patients.
Randomised Controlled Trial Parkinson's Disease Sleep DisorderStudy Protocols
Published study protocols are detailed plans that outline the objectives, methodology, statistical analyses, and organisation of a research study that have been made publicly available for others to review and use as a reference.
Presentation Slides
The ethanol extract from green kiwifruit peel enhances sleep duration and onset, proving to be a potential natural aid for treating sleep disorders.
Acupuncture can be safely applied as an alternative, adjuvant treatment in clinical practice to treat sleep disorders in postmenopausal women.
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