SP6
Also known as: San Yin Jiao
Recent Insights
SP6 acupressure's effectiveness for primary dysmenorrhea relief, indicating trained personnel-administered acupressure reduced pain immediately and up to 3 hours post-intervention
Period Pain SP6
Our findings suggest that acupressure at the SP6 acupoint may provide more effective pain relief than that of control treatment.
SP6
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Research Articles
Published research studies are articles that present the findings of original research that has undergone a peer-review process and has been made publicly available in scholarly journals, books or other media.
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Targeting fibrotic signaling pathways by EGCG as a therapeutic strategy for uterine fibroids
2023 May 25 Scientific Reports Islam MS, Parish M, Brennan JT, Winer BL, Segars JH
We observed that EGCG displayed greater efficacy than ICG-001 (β-catenin), SP600125 (JNK) and MK-2206 (AKT) inhibitors, and its effects were equivalent to verteporfin (YAP) or SB525334 (Smad) for regulating expression of key fibrotic mediators. These data indicate that EGCG exhibits anti-fibrotic effects in fibroid cells. These results provide insight into mechanisms behind the observed clinical efficacy of EGCG against uterine fibroids.
Network Pharmacology EGCG Uterine FibroidsThe effect of acupuncture and selection of acupoints on myelosuppression after chemotherapy
2022 Jan TMR Non-Drug Therapy Wang XZ, Zhang XY, Zhang YN, Xia L
Acupuncture significantly inhibited the decline in blood cell components (white blood cell count, platelet count, red blood cell count, and hemoglobin) except for neutrophils in patients with myelosuppression after chemotherapy. Acupoints, mainly from the bladder meridian, stomach meridian, and spleen meridian, were distributed in the limbs and back. Specific points such as ST36 and SP6 were frequently used, with ST36-SP6-RN6-SP10-RN4 identified as a central combination in acupuncture prescriptions for this population.
Systematic Review Meta-Analysis Acupuncture MyelosuppressionPotential Acupoint Prescriptions and Outcome Reporting for Acupuncture in Atopic Eczema: A Scoping Review
2021 Jun 26 Evidence-Based Complementary and Alternative Medicine Zeng Z, Li M, Zeng Y, Zhang J, Zhao Y, Lin Y, et al.
The preference of core acupoints is LI11, SP10, ST36, SP6, and LI4 in acupuncture clinical studies on eczema. This scoping review provides potential knowledge that should be considered as priority in future research of acupuncture for eczema.
Eczema AcupunctureEffectiveness of SP6 (Sanyinjiao) acupressure for relief of primary dysmenorrhea symptoms: A systematic review with meta- and sensitivity analyses
2016 Nov Complementary Therapies in Medicine Abaraogu UO, Igwe SE, Tabansi-Ochiogu CS
Systematic Review Meta-Analysis Period Pain SP6SP6 acupressure's effectiveness for primary dysmenorrhea relief, indicating trained personnel-administered acupressure reduced pain immediately and up to 3 hours post-intervention
Acupuncture or Acupressure at the Sanyinjiao (SP6) Acupoint for the Treatment of Primary Dysmenorrhea: A Meta-Analysis
2013 Feb 28 Evidence-Based Complementary and Alternative Medicine Chen MN, Chien LW, Liu CF
Systematic Review Meta-Analysis SP6Our findings suggest that acupressure at the SP6 acupoint may provide more effective pain relief than that of control treatment.
Research Insights
Insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.
SP6 acupressure's effectiveness for primary dysmenorrhea relief, indicating trained personnel-administered acupressure reduced pain immediately and up to 3 hours post-intervention
2016 Complementary Therapies in Medicine Effectiveness of SP6 (Sanyinjiao) acupressure for relief of primary dysmenorrhea symptoms: A systematic review with meta- and sensitivity analyses Abaraogu UO, Igwe SE, Tabansi-Ochiogu CS
Systematic Review Period Pain
The review initially identified 72 potential studies, but after eliminating duplicates and conducting screenings, only 13 studies were considered for inclusion. The review is the most extensive to date on SP6 acupressure for primary dysmenorrhea (PD), indicating its effectiveness when administered by trained personnel for immediate pain relief, reduction of anxiety, and potential general health improvement. However, the evidence remains limited and mostly consists of low-quality trials. Patient-administered acupressure might be beneficial with extended monthly application, though high-quality trials are required for such recommendations. The study highlights the need for future trials to specify diagnostic criteria for PD, given the lack of clarity in the included studies. Despite limitations, the findings suggest that self-administered acupressure holds promise for relieving PD symptoms.
Our findings suggest that acupressure at the SP6 acupoint may provide more effective pain relief than that of control treatment.
2013 Evidence-Based Complementary and Alternative Medicine Acupuncture or Acupressure at the Sanyinjiao (SP6) Acupoint for the Treatment of Primary Dysmenorrhea: A Meta-Analysis Chen MN, Chien LW, Liu CF
Systematic Review
This is the first systematic review to evaluate the effectiveness of acupuncture or acupressure at the SP6 acupoint for relieving pain associated with primary dysmenorrhea. Our findings suggest that acupuncture at the SP6 acupoint may not be more effective than acupuncture at an unrelated (GB39) acupoint for the relief of dysmenorrhea-associated pain (assessed using a VAS). In contrast, our findings suggest that acupressure at the SP6 acupoint may provide more effective relief from dysmenorrhea-associated pain than control interventions.
Clearly, there is a need for high-quality, randomized controlled trials to clarify the effectiveness of acupuncture/acupressure at the SP6 acupoint for the treatment of pain resulting from primary dysmenorrhea.
Review Articles
Review articles summarise and critically evaluate the current state of research on a specific topic or field by synthesising multiple primary research studies.
The effect of acupuncture and selection of acupoints on myelosuppression after chemotherapy
2022 Jan TMR Non-Drug Therapy Wang XZ, Zhang XY, Zhang YN, Xia L
Acupuncture significantly inhibited the decline in blood cell components (white blood cell count, platelet count, red blood cell count, and hemoglobin) except for neutrophils in patients with myelosuppression after chemotherapy. Acupoints, mainly from the bladder meridian, stomach meridian, and spleen meridian, were distributed in the limbs and back. Specific points such as ST36 and SP6 were frequently used, with ST36-SP6-RN6-SP10-RN4 identified as a central combination in acupuncture prescriptions for this population.
Systematic Review Meta-Analysis Acupuncture MyelosuppressionEffectiveness of SP6 (Sanyinjiao) acupressure for relief of primary dysmenorrhea symptoms: A systematic review with meta- and sensitivity analyses
2016 Nov Complementary Therapies in Medicine Abaraogu UO, Igwe SE, Tabansi-Ochiogu CS
Systematic Review Meta-Analysis Period Pain SP6SP6 acupressure's effectiveness for primary dysmenorrhea relief, indicating trained personnel-administered acupressure reduced pain immediately and up to 3 hours post-intervention
Acupuncture or Acupressure at the Sanyinjiao (SP6) Acupoint for the Treatment of Primary Dysmenorrhea: A Meta-Analysis
2013 Feb 28 Evidence-Based Complementary and Alternative Medicine Chen MN, Chien LW, Liu CF
Systematic Review Meta-Analysis SP6Our findings suggest that acupressure at the SP6 acupoint may provide more effective pain relief than that of control treatment.
Clinical Trials
Clinical trials are research studies that involve people and are conducted to evaluate the safety and efficacy of new treatments or interventions, such as drugs, medical devices, or behavioural therapies.
Study Protocols
Published study protocols are detailed plans that outline the objectives, methodology, statistical analyses, and organisation of a research study that have been made publicly available for others to review and use as a reference.
Presentation Slides
Systematic Review
SP6 acupressure's effectiveness for primary dysmenorrhea relief, indicating trained personnel-administered acupressure reduced pain immediately and up to 3 hours post-intervention
Abaraogu UO, Igwe SE, Tabansi-Ochiogu CS
Systematic Review
Our findings suggest that acupressure at the SP6 acupoint may provide more effective pain relief than that of control treatment.
Chen MN, Chien LW, Liu CF
Executive Summary
Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for SP6" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.
Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for SP6" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.
Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for SP6" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.
A Systematic Review published in 2016 in the journal Complementary Therapies in Medicine found that SP6 acupressure's effectiveness for primary dysmenorrhea relief, indicating trained personnel-administered acupressure reduced pain immediately and up to 3 hours post-intervention The review initially identified 72 potential studies, but after eliminating duplicates and conducting screenings, only 13 studies were considered for inclusion. The review is the most extensive to date on SP6 acupressure for primary dysmenorrhea (PD), indicating its effectiveness when administered by trained personnel for immediate pain relief, reduction of anxiety, and potential general health improvement. However, the evidence remains limited and mostly consists of low-quality trials. Patient-administered acupressure might be beneficial with extended monthly application, though high-quality trials are required for such recommendations. The study highlights the need for future trials to specify diagnostic criteria for PD, given the lack of clarity in the included studies. Despite limitations, the findings suggest that self-administered acupressure holds promise for relieving PD symptoms.
A Systematic Review published in 2013 in the journal Evidence-Based Complementary and Alternative Medicine found that Our findings suggest that acupressure at the SP6 acupoint may provide more effective pain relief than that of control treatment. This is the first systematic review to evaluate the effectiveness of acupuncture or acupressure at the SP6 acupoint for relieving pain associated with primary dysmenorrhea. Our findings suggest that acupuncture at the SP6 acupoint may not be more effective than acupuncture at an unrelated (GB39) acupoint for the relief of dysmenorrhea-associated pain (assessed using a VAS). In contrast, our findings suggest that acupressure at the SP6 acupoint may provide more effective relief from dysmenorrhea-associated pain than control interventions. Clearly, there is a need for high-quality, randomized controlled trials to clarify the effectiveness of acupuncture/acupressure at the SP6 acupoint for the treatment of pain resulting from primary dysmenorrhea.
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