Fermented gold kiwi extract exhibits antioxidant properties, providing protection to the stomach lining and reducing inflammation, making it promising for treating gastritis and gastric ulcers.
Animal Study Gastritis Kiwifruit
The researchers created a fermented powder from golden kiwi fruits, a process that enhances the fruit's bioactive compounds including organic acids, flavonoids, and carotenoids. They then studied its effects using animal models, specifically two rat models; one induced with gastritis via HCl/EtOH and the other with pyloric ligation. The goal was to examine the fermented gold kiwi's (FGK) antioxidative activity, appearing in a dose-dependent manner.
The obtained results demonstrated the protective effects of FGK in both animal models. The fermented kiwi notably suppressed inflammation biomarkers such as iNOS, COX-2, IL-6, and TNF-α, which are commonly associated with gastritis and gastric ulcers. It also increased the expression of PGE2, a molecule that protects the tissues. FGK was found to not only improve the appearance of the gastric lesion site but also enhance clinical symptoms and mucosal thickness. In the pyloric ligation model, it reduced gastric fluid volume, total acidity, free acidity, and pepsin activity, thereby showcasing overall gastric protective abilities.
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