Insights & Discussion
Honey exhibits significant anti-Helicobacter pylori activity, with at least 10% concentration proving effective in inhibiting gastric and duodenal ulcers, highlighting its therapeutic potential.
The research involved a comprehensive review of 53 articles from electronic databases such as Medline via Ovid Medline, Scopus, and ScienceDirect spanning from 2000 to 2018. Selection criteria focused on studies reporting honey's effects on H. pylori-induced gastric and duodenal ulcers. Nine chosen articles detailed the positive impact of honey, suggesting a minimum 10% concentration as effective against H. pylori. The review underscores the need for further exploration into honey's active components and molecular mechanisms.
The positive outcomes reported in selected studies support honey's potential in inhibiting H. pylori infections, emphasizing the need for further investigations to elucidate the active components and underlying molecular mechanisms. The review sets the stage for future research aiming to provide robust evidence for the use of honey in clinical settings.
Discover Related Insights
Ban Xia Xie Xin decoction has shown superior effectiveness and safety for treating chronic atrophic gastritis than patent medicine plus western medicine.
2020 PLOS One Efficacy of Banxia Xiexin decoction for chronic atrophic gastritis: A systematic review and meta-analysis Cao Y, Zheng Y, Niu J, Zhu C, Yang D, Rong F, et al.
Systematic Review Gastritis Stomach Ulcer
In an analysis of the clinical efficacy and safety of Banxia Xiexin decoction (BXD) for chronic atrophic gastritis (CAG) treatment, seven electronic databases, including Ovid, Embase, PubMed, Cochrane Library, and more, were used. The criteria for inclusion in the study were up until September 21, 2020. A Jadad scale coupled with Cochrane Collaboration's risk of bias tool evaluated methodological quality.
Out of the 1985 patients identified for analysis across 26 randomized controlled trials, it was found that BXD treatment provided more effective and safe results than Chinese patent medicine in conjunction with western medicine. Additionally, BXD was seen to improve symptom scores for stomach distending pain and belching. It was also observed that BXD effectively inhibited Helicobacter Pylori, improved HP-related inflammation, and alleviated the degree of glandular atrophy, intestinal metaplasia, and dysplasia of gastric mucosa. Despite the promising results, limitations were identified in relation to methodological quality and sample size across the studies.
Regular consumption of honey and yogurt may lower the prevalence of H. pylori infection and reduce the virulence of strains.
2017 Gastroenterology Research and Practice Influence of Dietary Factors onHelicobacter pyloriand CagA Seroprevalence in Bulgaria Yordanov D, Boyanova L, Markovska R, Ilieva J, Andreev N, Gergova G, et al.
Cohort Study H Pylori Honey Yoghurt
The study evaluated the association between dietary factors and the prevalence of an unnamed infection or virulence strain among 294 adult asymptomatic blood donors. The seroprevalence was evaluated using Enzyme-Linked Immunosorbent Assay. The study employed logistic regression in its analysis. Key dietary factors studied were the frequent consumption of honey and yogurt, specifically >5 days in a week. Smoking and consumption of other dietary factors were also considered.
In the analysis of results, it was found that frequent consumption of honey and yogurt was associated with reduced infection seroprevalence and virulence. Specifically, the study discovered a reverse association between honey or yogurt consumption and the prevalence of the virulence strain, marking it as a novel finding. The effect of other dietary factors and smoking were, however, found to be insignificant in disease prevalence. The study suggests that regular honey and yogurt consumption could enhance control in therapy for the infection.