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Eating plums, especially dried plums, significantly lowers LDL levels and total cholesterol levels, particularly in adults with existing health issues.
2024 Food Science & Nutrition The effects of plum products consumption on lipid profile in adults: A systematic review and dose–response meta‐analysis Heydarian A, Tahvilian N, Asbaghi O, Cheshmeh S, Nadery M, Aryaeian N
Systematic Review Cholesterol LDL Plum
The researchers conducted a systematic review and meta-analysis using keyword searches on databases such as PubMed, Scopus, and ISI Web of Science up to a specified date. They were on a mission to find eligible trials that would help ascertain the benefits of plum consumption on adult lipid profiles.
In their observation of the collected data, they concluded that plum, specifically dried plum consumption, had a noteworthy impact on LDL levels, mainly when the subjects were in an unhealthy state. This consumption led to a significant decrease in total cholesterol levels in the unhealthy subjects. Nevertheless, the study couldn't establish major changes in triglycerides and HDL concentrations as a result of the plum consumption.
Oat consumption can significantly improve lipid profiles, particularly reducing total cholesterol and LDL cholesterol, with potential positive effects on triglycerides and HDL cholesterol under certain conditions.
2023 Current Problems in Cardiology Effect of Oat (Avena sativa L.) Consumption on Lipid Profile With Focus on Triglycerides and High-density Lipoprotein Cholesterol (HDL-C): An Updated Systematic Review Amerizadeh A, Ghaheh HS, Vaseghi G, Farajzadegan Z, Asgary S
Systematic Review Cholesterol HDL-C Oats
In the methodology of this review study, information was gathered from various databases, including PubMed, Web of Science, and Google Scholar. The gathered data consisted of a total of 17 studies that explored the direct effects of oat consumption on lipid profiles. The focus of the studies included were the impacts of oat on levels of total cholesterol, VLDL, LDL-C, TG, and HDL-C. The review was meticulous, with a detailed examination of each study, particularly those showing positive effects of oat/beta-glucan consumption on triglycerides.
The review's results revealed that oat intake significantly reduces the levels of total cholesterol, VLDL, and LDL-C. The effect of oat ingestion on triglyceride levels was varied; of the 17 studies, 6 reported a decrease in triglycerides. Interestingly, one study showed an improvement in HDL-C levels following oat consumption. It was also observed that oat intake might effectively reduce triglycerides in healthy individuals and overweight people or those with diabetes or metabolic syndrome, especially when larger amounts of oat were consumed over a longer duration or in conjunction with a calorie-reducing diet. The use of oat together with certain dietary programs was suggested to potentially enhance its positive effects on lipid profiles.
Consumption of apple cider vinegar significantly improves certain risk factors for cardiometabolic syndrome, notably fasting blood glucose, glycosylated hemoglobin, and total cholesterol.
2023 Current Medicinal Chemistry The Effects of Apple Cider Vinegar on Cardiometabolic Risk Factors: A Systematic Review and Meta-analysis of Clinical Trials Dadkhah Tehrani S, Keshani M, Rouhani MH, Moallem SA, Bagherniya M, Sahebkar A
Systematic Review Apple Cider Vinegar Blood Sugar Cholesterol
This study applied a systematic review and meta-analysis of clinical trials found in PubMed, Scopus, and ISI Web of Science databases. In this process, trials evaluating the effects of apple cider vinegar consumption on cardiometabolic syndrome risk factors were sought. In total, 25 clinical trials were included in the study, these trials encompassed 1320 adult participants.
The consumed apple cider vinegar led to a general improvement in fasting blood glucose, glycosylated hemoglobin, and total cholesterol. However, for body mass index, insulin resistance, serum insulin, triglycerides, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol, no significant results were observed. Conducting a subgroup analysis, the study identified a significant decrease in fasting blood glucose, glycosylated hemoglobin, total cholesterol, and triglycerides in diabetic patients. Further, it was observed that the apple cider vinegar significantly reduced fasting blood glucose levels regardless of the duration of administration and also decreased triglycerides concentration when consumed for 12 weeks or more.
Sardines, being an affordable source of Omega-3 and other cardioprotective nutrients, can potentially reduce the need for Omega-3 supplementation and manage cardiometabolic diseases.
2023 Frontiers in Nutrition Eating more sardines instead of fish oil supplementation: Beyond omega-3 polyunsaturated fatty acids, a matrix of nutrients with cardiovascular benefits Santos HO, May TL, Bueno AA
Review Article Cardiovascular Disease Cholesterol High Blood Pressure
The abstract primarily acknowledges the importance of Omega-3 polyunsaturated fatty acids with respect to managing diseases related to heart health and metabolism, for instance, type 2 diabetes, hypertension, hypertriglyceridaemia, and fatty liver disease. However, these fatty acids are not the sole beneficial component of sardines. Minerals including but not limited to calcium, potassium, and magnesium as well as substances like taurine and arginine found in sardines have a significant role in controlling mild inflammation and oxidative stress which are usually present in cardiovascular diseases and hemodynamic dysfunction.
The results discussed in the abstract suggest a positive correlation between consumption of sardines and potential cardiometabolic benefits. By considering the dose-response relationship effects, a pragmatic approach towards consumption of nutrients was suggested. The intake of sardines was seen not only as a means of Omega-3 supplementation but also as a comprehensive approach to enhancing cardiovascular health. The abstract concludes with an emphasis on the many beneficial nutrients found in sardines besides Omega-3, underlining the need to shift the focus from synthetic supplementation to natural dietary improvement.
Jin Si Huang Ju tea, a traditional Chinese beverage, contains compounds that potentially reduce lipids, mitigate insulin resistance and reduce liver inflammation in vitro.
2023 European Journal of Medicinal Chemistry Effects and mechanism of action of Chrysanthemum morifolium (Jinsi Huangju) on hyperlipidemia and non-alcoholic fatty liver disease Li X, Li R, Wang X, Zhang X, Xiao Z, Wang H, et al.
Animal Study Cholesterol Chrysanthemum NAFLD
The researchers identified 14 compounds in the Jinsi Huangju tea using different spectroscopic techniques, 11 of which had not been previously identified in this plant. Two of these compounds, apigenin-7-O-6″-malonylglucoside and luteolin-7-O-6″-malonylglucoside, were synthesized for the first time with a yield of 1.2% over 5 steps.
In the findings, the natural compound apigenin-7-O-6″-malonylglucoside was found to inhibit the function of pancreatic lipase, reduce cellular lipid contents, and attenuate insulin resistance when tested in vitro. It was also observed to restore lipid and inflammatory profiles in plasma and the liver, as well as reduce hepatic steatosis in non-alcoholic fatty liver disease (NAFLD) mouse models. Thus, Jinsi Huangju and its active components are strong candidates for the development of drugs or functional foods that could provide a therapeutic strategy for hyperlipidaemia and NAFLD.
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