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Meta-Analysis highlights promising role of Guipi Decoction as adjuvant therapy for chronic heart failure
2023 Medicine Efficacy and safety of Guipi Decoction in the treatment of chronic heart failure: A systematic review and meta-analysis of randomized controlled trials Rong Y, Wu D, Li M, Teng J
Systematic Review Chronic Heart Failure Gui Pi Tang
Gui Pi decoction, when combined with Western medicine, significantly improved the clinical effective rate and cardiac function indicators. The biomarkers associated with chronic heart failure were also reduced. This suggests Gui Pi decoction could be a promising adjuvant therapy for chronic heart failure.
Combining Guipi Decoction (GPD) with western medicine holds promise for improving chronic heart failure treatment by enhancing effectiveness and cardiac measures
2023 Medicine Efficacy and safety of Guipi Decoction in the treatment of chronic heart failure: A systematic review and meta-analysis of randomized controlled trials Rong Y, Wu D, Li M, Teng J
Systematic Review Chronic Heart Failure Gui Pi Tang
Guipi decoction (GPD) for chronic heart failure (CHF), revealed that when combined with western medicine it improved clinical effectiveness, echocardiographic measures, and reduced CHF biomarker levels, suggesting potential benefits for cardiac function and CHF progression.
There is evidence to support significant improvements to total sleep time and sleep efficiency with the ingestion of tart cherries.
2023 Current Sleep Medicine Reports Too Sour to be True? Tart Cherries (Prunus cerasus) and Sleep: a Systematic Review and Meta-analysis Stretton B, Eranki A, Kovoor J, Bacchi S, Gupta A, Maddern G, et al.
Systematic Review Cherry Sleep
We identified a total of 277 unique records, from which 8 studies of low-moderate methodological quality were included in the systematic review. Meta-analysis of subjectively recalled sleep efficiency (SE) and total sleep time (TST) were not significant. Objective SE, however, was significantly higher in the cherry cohort when compared to placebo with an effect size of 0.63 (95% CI 0.29–0.97, P < 0.01). There was low associated heterogeneity (I2 = 0%). Objective TST was significantly higher in the cherry cohorts, with a pooled effect size of 1.21 (95% CI 0.83–1.58, P < 0.01). There was high associated heterogeneity (I2 = 81.5%).
Acupuncture may enhance the effectiveness of cognitive-behavioral therapy for people suffering from insomnia and related conditions.
2023 Sleep Medicine Clinics Acupuncture as an Adjunct Treatment to Cognitive-Behavioral Therapy for Insomnia Kutana S, Mao JJ, Garland SN
Theoretical Article Acupuncture Cognitive Behavioural Therapy
The research methodology used in this paper is mainly a theoretical analysis and discussion of the potential synergistic effects of combining cognitive-behavioral therapy for insomnia (CBT-I) and acupuncture. This involves analysis of the current evidence base for the efficacy of acupuncture in treating insomnia and related conditions, along with examination of the practical, logistical, and regulatory aspects of combining these two treatments.
In the discussion of their results, the researchers found that there is a growing body of evidence that supports the potential benefit of acupuncture in treating insomnia and its comorbidities, enhancing the current standard treatment approach of CBT-I. This appears to be an innovative approach that could potentially enhance the treatment effectiveness and outcomes for those struggling with insomnia, though it concurrently raises complex issues in terms of its practical and regulatory implementation.
The fermented jujube seeds extract significantly enhances sleep by binding to the GABA receptors, thus offers a promising natural alternative for sleep disorders treatment.
2023 Foods Sleep-Enhancing Effect of Water Extract from Jujube (Zizyphus jujuba Mill.) Seeds Fermented by Lactobacillus brevis L32 Bae GY, Ahn Y, Hong KB, Jung EJ, Suh HJ, Jo K
Experimental Study GABA Jujube Sleep
Methodology: An aqueous extract of jujube seeds (ZW) was fermented, following a starch-removing enzymatic degradation process, to increase its γ-aminobutyric acid (GABA) content, resulting in a fermented product (ZW-FM). The sleep-promoting effect of ZW-FM was evaluated using rodent models; specifically, sleep tests were performed on ICR mice with pentobarbital-induced sleep, while the electroencephalography analysis was undertaken in Sprague Dawley rats. Awakening relief effects of ZW-FM were assessed using a caffeine-induced insomnia model. To understand the mechanism, GABA receptor type A (GABA) antagonists were used.
Results: The groups given ZW-FM treatment displayed a longer sleep duration, particularly increased δ-wave time during non-rapid eye movement sleep, and reduced sleep latency. Particularly, the model treated with ZW-FM showed an increase in non-rapid-eye-movement sleep and a reduction in the REM sleep duration, brought about by caffeine treatment. The enhanced sleep induction caused by ZW-FM was hindered by GABA receptor antagonists, thereby validating the involvement of a GABAergic mechanism in promoting sleep.
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