Brain Activity
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Dark chocolate with high cocoa content can affect colonic functionality and stimulate certain brain regions in healthy adults.
Brain Activity Cocoa Dark Chocolate
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Research Articles
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Regulatory Effects of Acupuncture on Emotional Disorders in Patients With Menstrual Migraine Without Aura: A Resting-State fMRI Study
2021 Oct 04 Frontiers in Neuroscience Yutong Zhang, Ziwen Wang, Jiarong Du, Jixin Liu, Tao Xu, Xiao Wang, et al.
True acupuncture (TA) had a relatively better effect in reducing the frequency of migraine attack than sham acupuncture (SA). The two therapies have different modulation effects as TA regulates emotional disorders by modulating the frontal-limbic regions, and SA may modulate pain perception through the placebo effect on insula and by indirectly regulating emotional disorders.
Randomised Controlled TrialEffect of cocoa on the brain and gut in healthy subjects: a randomised controlled trial
2019 Jan 24 British Journal of Nutrition Fox M, Meyer-Gerspach AC, Wendebourg MJ, Gruber M, Heinrich H, Sauter M, et al.
Randomised Controlled Trial Digestive Health Diarrhoea Brain Activity Dark Chocolate CocoaDark chocolate with high cocoa content can affect colonic functionality and stimulate certain brain regions in healthy adults.
The neuroprotective effects of cocoa flavanol and its influence on cognitive performance
2013 Feb 05 British Journal of Clinical Pharmacology Nehlig A
Review Article Cocoa Alzheimer's Disease Cognitive FunctionCocoa and chocolate, rich in antioxidant molecules like epicatechin, enhance brain health, stimulate brain perfusion, and reduce the risk of Alzheimer's disease and stroke.
Pomegranate Juice Augments Memory and fMRI Activity in Middle-Aged and Older Adults with Mild Memory Complaints
2013 Jan Evidence-Based Complementary and Alternative Medicine Bookheimer SY, Renner BA, Ekstrom A, Li Z, Henning SM, Brown JA, et al.
Experimental Study Randomised Controlled Trial Memory Pomegranate Brain HealthPomegranate juice can enhance memory function and brain activity in tasks related to verbal and visual memory in older adults experiencing memory problems.
Research Insights
Insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.
Dark chocolate with high cocoa content can affect colonic functionality and stimulate certain brain regions in healthy adults.
2019 British Journal of Nutrition Effect of cocoa on the brain and gut in healthy subjects: a randomised controlled trial Fox M, Meyer-Gerspach AC, Wendebourg MJ, Gruber M, Heinrich H, Sauter M, et al.
Randomised Controlled Trial Cocoa Dark Chocolate Diarrhoea
The study involved a controlled, randomised experiment including healthy volunteers who were given 100g of either dark chocolate (with 72% cocoa content) or white chocolate (with no cocoa content) for five consecutive days. The volunteers then recorded any abdominal symptoms and stool consistency using the Bristol Stool Score. Gastric emptying as well as intestinal and colonic transit time were examined using scintigraphy and marker studies, while the activity in different brain regions was assessed using combined positron emission tomography-computed tomography imaging techniques.
The study found that dark chocolate did not alter the functionality of the upper gastrointestinal tract. Nevertheless, it was observed that the consumption of dark chocolate led to harder stool consistency. As for the brain, an increased uptake of fluorodeoxyglucose was noticed within the visual cortex, with other regions like the somatosensory, motor and pre-frontal cortices also showing heightened activity. This suggests that dark chocolate may potentially influence certain brain functions.
Cocoa and chocolate, rich in antioxidant molecules like epicatechin, enhance brain health, stimulate brain perfusion, and reduce the risk of Alzheimer's disease and stroke.
2013 British Journal of Clinical Pharmacology The neuroprotective effects of cocoa flavanol and its influence on cognitive performance Nehlig A
Review Article Alzheimer's Disease Cocoa Cognitive Function
The study involved taking a comprehensive look at the substances contained in cocoa powder and chocolate, their absorption into the brain, and their resulting stimulatory effects on multiple areas of the brain, particularly those connected to comprehension and memory. It also delved into the beneficial effects of epicatechin, a flavonoid found abundantly in cocoa and chocolate, which showed improvements in cognition in both animals and humans. Interestingly, the research showed that the consumption of chocolate could induce mood enhancement, elaborating on its common consumption during times of emotional stress.
The study further investigated flavonoids' preservation of cognitive abilities in rats during aging, noting the reduced risk of developing Alzheimer's disease and the decreased likelihood of stroke in humans, demonstrating their wider effects beyond just mood enhancement. The research then looked into flavonoids' interactions within the various signaling pathways related to proteins and lipids in the brain, shedding light on how they inhibit neuron death from neurotoxic elements like oxygen radicals, all while promoting neuron survival and synaptic plasticity. The overall intent of the research was to gather and examine the available data regarding the effects of cocoa and chocolate on brain health and cognitive capacities.
Pomegranate juice can enhance memory function and brain activity in tasks related to verbal and visual memory in older adults experiencing memory problems.
2013 Evidence-Based Complementary and Alternative Medicine Pomegranate Juice Augments Memory and fMRI Activity in Middle-Aged and Older Adults with Mild Memory Complaints Bookheimer SY, Renner BA, Ekstrom A, Li Z, Henning SM, Brown JA, et al.
Experimental Study Brain Health Memory Pomegranate
The study was a preliminary, placebo-controlled, randomized trial involving 32 older participants with memory complaints. They were randomly tasked to consume 8 ounces of either pomegranate juice or a placebo drink that had a similar flavor daily for a duration of 4 weeks. Before and after the study duration, the subjects underwent memory tests and functional MRI scans while involved in cognitive tasks. Additionally, blood samples were extracted to ascertain peripheral biomarkers. The test subjects and investigators were oblivious to the groupings to ensure objectivity.
The results from the study pointed out that the group that had pomegranate juice had notable improvements in their verbal memory as determined by the Buschke selective reminding test and also a rise in their antioxidant capacity. This group also recorded increased fMRI activity during tasks related to verbal and visual memory in comparison to the placebo group. This may suggest that consumption of pomegranate juice may boost memory function by elevating functional brain activity during tasks.
Review Articles
Review articles summarise and critically evaluate the current state of research on a specific topic or field by synthesising multiple primary research studies.
Clinical Trials
Clinical trials are research studies that involve people and are conducted to evaluate the safety and efficacy of new treatments or interventions, such as drugs, medical devices, or behavioural therapies.
Regulatory Effects of Acupuncture on Emotional Disorders in Patients With Menstrual Migraine Without Aura: A Resting-State fMRI Study
2021 Oct 04 Frontiers in Neuroscience Yutong Zhang, Ziwen Wang, Jiarong Du, Jixin Liu, Tao Xu, Xiao Wang, et al.
True acupuncture (TA) had a relatively better effect in reducing the frequency of migraine attack than sham acupuncture (SA). The two therapies have different modulation effects as TA regulates emotional disorders by modulating the frontal-limbic regions, and SA may modulate pain perception through the placebo effect on insula and by indirectly regulating emotional disorders.
Randomised Controlled TrialEffect of cocoa on the brain and gut in healthy subjects: a randomised controlled trial
2019 Jan 24 British Journal of Nutrition Fox M, Meyer-Gerspach AC, Wendebourg MJ, Gruber M, Heinrich H, Sauter M, et al.
Randomised Controlled Trial Digestive Health Diarrhoea Brain Activity Dark Chocolate CocoaDark chocolate with high cocoa content can affect colonic functionality and stimulate certain brain regions in healthy adults.
Pomegranate Juice Augments Memory and fMRI Activity in Middle-Aged and Older Adults with Mild Memory Complaints
2013 Jan Evidence-Based Complementary and Alternative Medicine Bookheimer SY, Renner BA, Ekstrom A, Li Z, Henning SM, Brown JA, et al.
Experimental Study Randomised Controlled Trial Memory Pomegranate Brain HealthPomegranate juice can enhance memory function and brain activity in tasks related to verbal and visual memory in older adults experiencing memory problems.
Study Protocols
Published study protocols are detailed plans that outline the objectives, methodology, statistical analyses, and organisation of a research study that have been made publicly available for others to review and use as a reference.
Presentation Slides
Randomised Controlled Trial
Dark chocolate with high cocoa content can affect colonic functionality and stimulate certain brain regions in healthy adults.
Fox M, Meyer-Gerspach AC, Wendebourg MJ, Gruber M, Heinrich H, Sauter M, Woelnerhanssen B, Koeberle D, Juengling F
Review Article
Cocoa and chocolate, rich in antioxidant molecules like epicatechin, enhance brain health, stimulate brain perfusion, and reduce the risk of Alzheimer's disease and stroke.
Nehlig A
Experimental Study
Pomegranate juice can enhance memory function and brain activity in tasks related to verbal and visual memory in older adults experiencing memory problems.
Bookheimer SY, Renner BA, Ekstrom A, Li Z, Henning SM, Brown JA, Jones M, Moody T, Small GW
Executive Summary
Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Brain Activity" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.
Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Brain Activity" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.
Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Brain Activity" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.
A Randomised Controlled Trial published in 2019 in the journal British Journal of Nutrition found that Dark chocolate with high cocoa content can affect colonic functionality and stimulate certain brain regions in healthy adults. The study involved a controlled, randomised experiment including healthy volunteers who were given 100g of either dark chocolate (with 72% cocoa content) or white chocolate (with no cocoa content) for five consecutive days. The volunteers then recorded any abdominal symptoms and stool consistency using the Bristol Stool Score. Gastric emptying as well as intestinal and colonic transit time were examined using scintigraphy and marker studies, while the activity in different brain regions was assessed using combined positron emission tomography-computed tomography imaging techniques. The study found that dark chocolate did not alter the functionality of the upper gastrointestinal tract. Nevertheless, it was observed that the consumption of dark chocolate led to harder stool consistency. As for the brain, an increased uptake of fluorodeoxyglucose was noticed within the visual cortex, with other regions like the somatosensory, motor and pre-frontal cortices also showing heightened activity. This suggests that dark chocolate may potentially influence certain brain functions.
A Review Article published in 2013 in the journal British Journal of Clinical Pharmacology found that Cocoa and chocolate, rich in antioxidant molecules like epicatechin, enhance brain health, stimulate brain perfusion, and reduce the risk of Alzheimer's disease and stroke. The study involved taking a comprehensive look at the substances contained in cocoa powder and chocolate, their absorption into the brain, and their resulting stimulatory effects on multiple areas of the brain, particularly those connected to comprehension and memory. It also delved into the beneficial effects of epicatechin, a flavonoid found abundantly in cocoa and chocolate, which showed improvements in cognition in both animals and humans. Interestingly, the research showed that the consumption of chocolate could induce mood enhancement, elaborating on its common consumption during times of emotional stress. The study further investigated flavonoids' preservation of cognitive abilities in rats during aging, noting the reduced risk of developing Alzheimer's disease and the decreased likelihood of stroke in humans, demonstrating their wider effects beyond just mood enhancement. The research then looked into flavonoids' interactions within the various signaling pathways related to proteins and lipids in the brain, shedding light on how they inhibit neuron death from neurotoxic elements like oxygen radicals, all while promoting neuron survival and synaptic plasticity. The overall intent of the research was to gather and examine the available data regarding the effects of cocoa and chocolate on brain health and cognitive capacities.
A Experimental Study published in 2013 in the journal Evidence-Based Complementary and Alternative Medicine found that Pomegranate juice can enhance memory function and brain activity in tasks related to verbal and visual memory in older adults experiencing memory problems. The study was a preliminary, placebo-controlled, randomized trial involving 32 older participants with memory complaints. They were randomly tasked to consume 8 ounces of either pomegranate juice or a placebo drink that had a similar flavor daily for a duration of 4 weeks. Before and after the study duration, the subjects underwent memory tests and functional MRI scans while involved in cognitive tasks. Additionally, blood samples were extracted to ascertain peripheral biomarkers. The test subjects and investigators were oblivious to the groupings to ensure objectivity. The results from the study pointed out that the group that had pomegranate juice had notable improvements in their verbal memory as determined by the Buschke selective reminding test and also a rise in their antioxidant capacity. This group also recorded increased fMRI activity during tasks related to verbal and visual memory in comparison to the placebo group. This may suggest that consumption of pomegranate juice may boost memory function by elevating functional brain activity during tasks.
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