Research Articles
Published research studies are articles that present the findings of original research that has undergone a peer-review process and has been made publicly available in scholarly journals, books or other media.
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- Registered users can submit any published journal article that has a unique DOI (Digital Object Identifier) name or link to Research Hub.
- For example, you can paste the full DOI link:
https://doi.org/10.1109/5.771073 or just the DOI name: 10.1109/5.771073 into the field above and click submit.
- The person who is first to submit a valid article to Research Hub will forever be credited for it, and every article submission earns you +6 Research Points.
Research Insights
Insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.
The ethanol extract from adzuki beans significantly reduces lung metastasis and invasion of melanoma cells, showing potential for functional food development.
Network Pharmacology Anticancer Melanoma
The methodology of the study involved extracting the 40% ethanol eluent from the fraction of hot-water extract from adzuki beans adsorbed onto a type of resin. This extract, dubbed EtEx.40, was then tested on B16-BL6 melanoma cells, examining specifically its effects on adhesion, migration, and invasion into extracellular matrix components and their invasion into reconstituted basement membrane (colloquially referred to as matrigel), while ensuring it did not affect cell proliferation in vitro.
The results illustrated a significant difference in the presence of tumor colonies when treated with EtEx.40. The extract showed a considerable inhibitory effect on the experimental lung metastasis, as well as the invasion of the melanoma cells. Furthermore, the adhesion and migration of the melanoma cells into the extracellular matrix components were also reduced. The results demonstrated a strong antimetastatic role of the ethanol extract of adzuki beans.
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Review Articles
Review articles summarise and critically evaluate the current state of research on a specific topic or field by synthesising multiple primary research studies.
Clinical Trials
Clinical trials are research studies that involve people and are conducted to evaluate the safety and efficacy of new treatments or interventions, such as drugs, medical devices, or behavioural therapies.
Study Protocols
Published study protocols are detailed plans that outline the objectives, methodology, statistical analyses, and organisation of a research study that have been made publicly available for others to review and use as a reference.
Presentation Slides
Chinese Medicine Research Hub
Network Pharmacology
The ethanol extract from adzuki beans significantly reduces lung metastasis and invasion of melanoma cells, showing potential for functional food development.
2023 Bioscience, Biotechnology, and Biochemistry Potential Ability of Hot Water Adzuki (Vigna angularis) Extracts to Inhibit the Adhesion, Invasion, and Metastasis of Murine B16 Melanoma Cells
ITOH T, UMEKAWA H, FURUICHI Y
Executive Summary
Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Lung Metastasis" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.
Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Lung Metastasis" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.
Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Lung Metastasis" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.
A Network Pharmacology published in 2023 in the journal Bioscience, Biotechnology, and Biochemistry found that The ethanol extract from adzuki beans significantly reduces lung metastasis and invasion of melanoma cells, showing potential for functional food development. The methodology of the study involved extracting the 40% ethanol eluent from the fraction of hot-water extract from adzuki beans adsorbed onto a type of resin. This extract, dubbed EtEx.40, was then tested on B16-BL6 melanoma cells, examining specifically its effects on adhesion, migration, and invasion into extracellular matrix components and their invasion into reconstituted basement membrane (colloquially referred to as matrigel), while ensuring it did not affect cell proliferation in vitro.
The results illustrated a significant difference in the presence of tumor colonies when treated with EtEx.40. The extract showed a considerable inhibitory effect on the experimental lung metastasis, as well as the invasion of the melanoma cells. Furthermore, the adhesion and migration of the melanoma cells into the extracellular matrix components were also reduced. The results demonstrated a strong antimetastatic role of the ethanol extract of adzuki beans.
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The ethanol extract from adzuki beans significantly reduces lung metastasis and invasion of melanoma cells, showing potential for functional food development.