Research Articles
Published research studies are articles that present the findings of original research that has undergone a peer-review process and has been made publicly available in scholarly journals, books or other media.
How to submit an article:
- Registered users can submit any published journal article that has a unique DOI (Digital Object Identifier) name or link to Research Hub.
- For example, you can paste the full DOI link:
https://doi.org/10.1109/5.771073
or just the DOI name: 10.1109/5.771073
into the field above and click submit.
- The person who is first to submit a valid article to Research Hub will forever be credited for it, and every article submission earns you +6 Research Points.
The Efficacy and Mechanism of Chinese Herbal Medicine on Diabetic Kidney Disease
2019 Aug 25 Journal of Diabetes Research Lu Z, Zhong Y, Liu W, Xiang L, Deng Y
With the in-depth researches on the efficacy and action mechanism of TCM in treating DKD, TCM may play a great role in alleviating proteinuria and delaying end-stage renal disease (ESRD).
Review Article Chronic Kidney Disease Chinese herbal medicine for diabetic kidney disease: a systematic review and meta-analysis of randomised placebo-controlled trials
2019 Apr BMJ Open Zhang L, Yang L, Shergis J, Zhang L, Zhang AL, Guo X, et al.
Systematic Review Meta-Analysis Diabetic Kidney Disease Chronic Kidney Disease Chinese herbal medicine may be effective and safe for treating diabetic kidney disease, although evidence quality varies.
Chinese herbal medicine for diabetic kidney disease: a systematic review and meta-analysis of randomised placebo-controlled trials
2019 Apr BMJ Open Zhang L, Yang L, Shergis J, Zhang L, Zhang AL, Guo X, et al.
The study concludes that CHM, when used as an adjunct to conventional treatments, shows greater reduction in albuminuria and improved glomerular filtration rate in DKD patients.
Systematic Review Meta-Analysis Albuminuria Type 2 Diabetes GFR Diabetic Kidney Disease
Research Insights
Insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.
Chinese herbal medicine may be effective and safe for treating diabetic kidney disease, although evidence quality varies.
Systematic Review Chronic Kidney Disease
The systematic review and meta-analysis comprised randomized controlled trials comparing the use of oral Chinese herbal medicine (CHM) to a placebo, involving a comprehensive search strategy and selecting from over 7000 articles, resulting in 20 studies with a total of 2719 participants. Potential bias was minimized by only including studies that pitted CHM against a placebo. In addition, an a priori subgroups analysis was conducted to identify potential candidate formulae and frequently used herbs for further exploration.
Despite these measures, the overall evidence ranged from moderate to very low quality due to unclear randomization procedures, substantial variations in outcome measures, and reduced external validity. The latter was affected by factors such as multi-ingredient herbal formulae, brief follow-up periods, limited numbers of clinical events, and the inclusion of older patients with less advanced disease.
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Clinical Trials
Clinical trials are research studies that involve people and are conducted to evaluate the safety and efficacy of new treatments or interventions, such as drugs, medical devices, or behavioural therapies.
Study Protocols
Published study protocols are detailed plans that outline the objectives, methodology, statistical analyses, and organisation of a research study that have been made publicly available for others to review and use as a reference.
Presentation Slides
Chinese Medicine Research Hub
Systematic Review
Chinese herbal medicine may be effective and safe for treating diabetic kidney disease, although evidence quality varies.
2019 BMJ Open Chinese herbal medicine for diabetic kidney disease: a systematic review and meta-analysis of randomised placebo-controlled trials
Zhang L, Yang L, Shergis J, Zhang L, Zhang AL, Guo X, Qin X, Johnson D, Liu X, Lu C, Xue CC, Mao W
Executive Summary
Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Diabetic Kidney Disease" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.
Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Diabetic Kidney Disease" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.
Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Diabetic Kidney Disease" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.
A Systematic Review published in 2019 in the journal BMJ Open found that Chinese herbal medicine may be effective and safe for treating diabetic kidney disease, although evidence quality varies. The systematic review and meta-analysis comprised randomized controlled trials comparing the use of oral Chinese herbal medicine (CHM) to a placebo, involving a comprehensive search strategy and selecting from over 7000 articles, resulting in 20 studies with a total of 2719 participants. Potential bias was minimized by only including studies that pitted CHM against a placebo. In addition, an a priori subgroups analysis was conducted to identify potential candidate formulae and frequently used herbs for further exploration.
Despite these measures, the overall evidence ranged from moderate to very low quality due to unclear randomization procedures, substantial variations in outcome measures, and reduced external validity. The latter was affected by factors such as multi-ingredient herbal formulae, brief follow-up periods, limited numbers of clinical events, and the inclusion of older patients with less advanced disease.