Rutin
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The primary ingredient of Shenling Baizhu powder, Rutin, can improve polycystic ovary syndrome and postmenopausal osteoporosis by binding to the aromatic hydrocarbon receptor, thus inhibiting cell apoptosis.
Osteoporosis PCOS Postmenopausal
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Research Articles
Published research studies are articles that present the findings of original research that has undergone a peer-review process and has been made publicly available in scholarly journals, books or other media.
The effects of acupuncture on clinical efficacy and steady-state visual evoked potentials in insomnia patients with emotional disorders: A randomized single-blind sham-controlled trial
2023 Jan 18 Frontiers in Neurology Leixiao Zhang, Yanli Deng, Ruting Hui, Yu Tang, Siyi Yu, Ying Li, et al.
Acupuncture have a good clinical effect on patients with insomnia and emotional disorders and have a significant regulatory effect on abnormally excited brain potentials.
Randomised Controlled Trial AcupuncturePrevention of polycystic ovary syndrome and postmenopausal osteoporosis by inhibiting apoptosis with Shenling Baizhu powder compound
2022 Oct 28 PeerJ Liang J, Bao A, Ma H, Dong W, Li W, Wu X, et al.
Network Pharmacology PCOS Osteoporosis Shen Ling Bai Zhu San Postmenopausal RutinThe primary ingredient of Shenling Baizhu powder, Rutin, can improve polycystic ovary syndrome and postmenopausal osteoporosis by binding to the aromatic hydrocarbon receptor, thus inhibiting cell apoptosis.
Antiosteoporosis Studies of 20 Medicine Food Homology Plants Containing Quercetin, Rutin, and Kaempferol: TCM Characteristics, In Vivo and In Vitro Activities, Potential Mechanisms, and Food Functions
2022 Mar 31 Evidence-Based Complementary and Alternative Medicine Shen D, Feng Y, Zhang X, Gong L, Liu J, Li Y, et al.
The study concludes that these 20 MFH plants, along with quercetin, rutin, and kaempferol, could be used as daily food supplements for the prevention and treatment against osteoporosis.
Review Article Kaempferol Quercetin Osteoporosis Rutin
Anticancer drug discovery from Iranian Chrysanthemum cultivars through system pharmacology exploration and experimental validation
2021 Jun 03 Scientific Reports Hodaei M, Rahimmalek M, Behbahani M
The study found that Chrysanthemum extracts inhibited the proliferation of MCF7 cells in a dose- and cultivar-dependent manner, with rutin identified as a promising multi-targeted herbal ingredient with anticancer effects.
Experimental Study Network Pharmacology Chrysanthemum Breast Cancer Rutin Anticancer
Antioxidant Properties and Nutritional Composition of Matcha Green Tea
2020 Apr 12 Foods Jakubczyk K, Kochman J, Kwiatkowska A, Kałduńska J, Dec K, Kawczuga D, et al.
Network Pharmacology Matcha AntioxidantThe antioxidant potential and substance levels in Matcha tea is affected by the harvest period and water temperature used for preparation.
Research Insights
Insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.
The primary ingredient of Shenling Baizhu powder, Rutin, can improve polycystic ovary syndrome and postmenopausal osteoporosis by binding to the aromatic hydrocarbon receptor, thus inhibiting cell apoptosis.
2022 PeerJ Prevention of polycystic ovary syndrome and postmenopausal osteoporosis by inhibiting apoptosis with Shenling Baizhu powder compound Liang J, Bao A, Ma H, Dong W, Li W, Wu X, et al.
Network Pharmacology Osteoporosis PCOS Postmenopausal
In this study, the active ingredients of Shenling Baizhu powder were identified using a Chinese medicine database, and Rutin emerged as having the highest binding affinity to the aromatic hydrocarbon receptor. This was determined through molecular dynamics simulation, eliminating any ambiguity. Then, to assess the efficacy of Rutin, it was used therapeutically on ovarian granulosa and osteoblast cell lines, with varying concentrations to determine the optimum dosage.
Analyzing the results showed that the introduction of Rutin to both ovarian granulosa and osteoblast cell lines resulted in modified protein expressions, indicative of cellular adjustments. Specifically, expressions of the apoptosis-associated protein and the aromatic hydrocarbon receptor, among others, were decreased while the expression of protein Bcl-2 was increased. Moreover, cell proliferation was seen to significantly accelerate in both cell lines after treatment with Rutin.
The antioxidant potential and substance levels in Matcha tea is affected by the harvest period and water temperature used for preparation.
2020 Foods Antioxidant Properties and Nutritional Composition of Matcha Green Tea Jakubczyk K, Kochman J, Kwiatkowska A, Kałduńska J, Dec K, Kawczuga D, et al.
Network Pharmacology Antioxidant Matcha
The study's methodology was set to evaluate the antioxidant capacity and significant component levels of traditional and daily Matcha green tea, originating from Japan. It focused on the content of essential vitamins, flavonoids, and other polyphenols. The variations in these components were examined by making infusions at different temperatures - 25°C, 70°C, 80°C, and 90°C. Approximately 1.75g of the plant material was used with 100mL of distilled water in these preparations. The comparison was made between Matcha tea from the first and second harvests, as well as from the second and third harvests.
In the discussion of results, infusions made from the daily Matcha harvest, especially the one prepared at 90°C, were observed to have the highest amount of substances possessing antioxidant properties. Notably, the concentrations of these beneficial substances tended to vary according to the timing of the plant's harvest and the temperature of water used for infusion preparation. Particularly, flavonoids, polyphenols, and vitamin C showed appreciable fluctuation across these variables, confirming a vital link between preparation details and the health benefits furnished by Matcha green tea.
Review Articles
Review articles summarise and critically evaluate the current state of research on a specific topic or field by synthesising multiple primary research studies.
Antiosteoporosis Studies of 20 Medicine Food Homology Plants Containing Quercetin, Rutin, and Kaempferol: TCM Characteristics, In Vivo and In Vitro Activities, Potential Mechanisms, and Food Functions
2022 Mar 31 Evidence-Based Complementary and Alternative Medicine Shen D, Feng Y, Zhang X, Gong L, Liu J, Li Y, et al.
The study concludes that these 20 MFH plants, along with quercetin, rutin, and kaempferol, could be used as daily food supplements for the prevention and treatment against osteoporosis.
Review Article Kaempferol Quercetin Osteoporosis Rutin
Evaluation of antiviral activities of Houttuynia cordata Thunb. extract, quercetin, quercetrin and cinanserin on murine coronavirus and dengue virus infection
2016 Jan Asian Pacific Journal of Tropical Medicine Chiow KH, Phoon MC, Putti T, Tan BKH, Chow VT
The compounds in H. cordata contribute to the superior antiviral efficacy of the EA fraction which lacked cytotoxicity in vitro and acute toxicity in vivo. H. cordata has much potential for the development of antiviral agents against coronavirus and dengue infections.
Review ArticleClinical Trials
Clinical trials are research studies that involve people and are conducted to evaluate the safety and efficacy of new treatments or interventions, such as drugs, medical devices, or behavioural therapies.
Presentation Slides
The primary ingredient of Shenling Baizhu powder, Rutin, can improve polycystic ovary syndrome and postmenopausal osteoporosis by binding to the aromatic hydrocarbon receptor, thus inhibiting cell apoptosis.
The antioxidant potential and substance levels in Matcha tea is affected by the harvest period and water temperature used for preparation.
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