Glucose Metabolism
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Coffee consumption, in the long term, improves glucose metabolism but may cause unfavourable acute effects.
Blood Sugar Glucose
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Chinese herbal medicine alleviates the pathogenesis of polycystic ovary syndrome by improving oxidative stress and glucose metabolism via mitochondrial Sirtuin 3 signaling
2023 Jan Phytomedicine Zhang Q, Ren J, Wang F, Li M, Pan M, Zhang H, et al.
Bu Shen Tian Jing Formula (BSTJF) effectively alleviated the pathogenesis of polycystic ovary syndrome (PCOS) by improving oxidative stress and glucose metabolism via mitochondrial SIRT3 and the following insulin signaling pathway. This study innovatively revealed the action mechanism of CHM in treating PCOS.
Animal Study Bu Shen Tian Jing Formula (BSTJF) Bu Shen Tian Jing FormulaChinese Herbal Medicine for Type 2 Diabetes Mellitus With Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis
2022 Jun 27 Frontiers in Pharmacology Peng S, Liu L, Xie Z, Zhang X, Xie C, Ye S, et al.
The CHM in combination with WM seems to be more beneficial in T2DM with NAFLD patients in improving lipid and glucose metabolism, liver function, and insulin resistance as well as improving overall efficiency and reducing body weight.
Systematic Review Meta-Analysis Chinese Herbal MedicinePhytochemistry, bioactivities and future prospects of mulberry leaves: A review
2022 Mar Food Chemistry Ma G, Chai X, Hou G, Zhao F, Meng Q
MLs and their extracts may be a promising treatment option for regulating glucose metabolism and lipid metabolism as well as anticancer effects. The dominant compounds responsible for the pharmacological effects of resisting oxidation, reducing blood sugar and lipids, resisting cancer and resisting inflammation in MLs include phenols, flavonoids, polysaccharides and alkaloids. Furthermore, ML suggests ability to inhibit multiple oxidase as well as anti-diabetic effects however more research is needed to yield stronger suggestions
Review Article Sang YeConsumption of sesame seeds and sesame products has favorable effects on blood glucose levels but not on insulin resistance: A systematic review and meta‐analysis of controlled clinical trials
2022 Jan 18 Phytotherapy Research Sohouli MH, Haghshenas N, Hernández‐Ruiz , Shidfar F
Systematic Review Meta-Analysis Blood Sugar SesameConsumption of sesame seeds and its products positively influences human glucose metabolism, potentially making it a beneficial addition to glucose-lowering diets.
The Effect of Acupuncture on Glucose Metabolism and Lipid Profiles in Patients with PCOS: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
2021 Mar 22 Evidence-Based Complementary and Alternative Medicine Ruqun Zheng, Peng Qing, Mei Han, Jinlong Song, Min Hu, Hongxia Ma, et al.
Systematic Review Meta-AnalysisAcupuncture could improve body mass index, waist-to-hip ratio as well as insulin resistance (HOMA-IR) in patients with PCOS.
Research Insights
Insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.
Consumption of sesame seeds and its products positively influences human glucose metabolism, potentially making it a beneficial addition to glucose-lowering diets.
2022 Phytotherapy Research Consumption of sesame seeds and sesame products has favorable effects on blood glucose levels but not on insulin resistance: A systematic review and meta‐analysis of controlled clinical trials Sohouli MH, Haghshenas N, Hernández‐Ruiz , Shidfar F
Systematic Review Blood Sugar Sesame
The methodology involved conducting a systematic review and meta-analysis on the effect of sesame seeds consumption on blood glucose and insulin resistance in adults. The researchers gathered data from recognized academic resources like PubMed/MEDLINE, SCOPUS, Web of Science, Google Scholar, and EMBASE, which included controlled clinical trials up until February 2021. The sesame products in these trials ranged from sesame oil, sesamin, and tahini, with the intervention period lasting from 45 days to 9 weeks.
The results illustrate that the intake of sesame and its products significantly improved fasting blood glucose and Hemoglobin A1c levels. Nonetheless, the results regarding fasting serum insulin and the homeostatic model assessment for insulin resistance were not found to have any significant relation. Hence, the consumption of sesame might be a beneficial supplement for managing glucose levels in humans.
Acupuncture could improve body mass index, waist-to-hip ratio as well as insulin resistance (HOMA-IR) in patients with PCOS.
2021 Evidence-Based Complementary and Alternative Medicine The Effect of Acupuncture on Glucose Metabolism and Lipid Profiles in Patients with PCOS: A Systematic Review and Meta-Analysis of Randomized Controlled Trials Ruqun Zheng, Peng Qing, Mei Han, Jinlong Song, Min Hu, Hongxia Ma, et al.
Systematic Review
Overall, we found that acupuncture was closely associated with decreased BMI, WHR, FPG, and HOMA-IR and that acupuncture could significantly improve HOMA-IR and the level of fasting glucose in patients with PCOS, which confirms previous reports. It is also reported that acupuncture can decrease BMI and WHR. FINS, 2hFPG, and 2hFINS were reduced in the acupuncture groups, but these differences were not significantly different.
The results of the lipid profile were reported in a few studies, and we found that acupuncture significantly improved triglycerides levels, while the differences in total cholesterol, LDL-C, and HDL-C were not significant.
Acupuncture seems to be associated with a few adverse events, and the reported adverse events, such as bleeding, were mild and transient, demonstrating that acupuncture is safe and reliable. Thus, we conclude that acupuncture, compared with standard therapy, is more effective and safer in improving glucose metabolism and insulin sensitivity in patients with PCOS.
Coffee consumption, in the long term, improves glucose metabolism but may cause unfavourable acute effects.
2019 Journal of Traditional and Complementary Medicine Effects of coffee consumption on glucose metabolism: A systematic review of clinical trials Reis CEG, Dórea JG, da Costa THM
Systematic Review Blood Sugar Glucose
Researchers undertook a systematic review to evaluate the impact of coffee consumption on glucose metabolism. They scanned two electronic databases, PubMed and Web of Science, for relevant studies published till September 2017. After thorough scrutiny, eight clinical trials involving 247 participants were earmarked for analysis. These trials were divided into short-term (1-3 hours) and long-term (2-16 weeks) studies for distinct evaluation. The participants' characteristics, major discoveries, and study quality were all meticulously noted and analysed.
The initial short-term studies revealed that consumption of caffeinated coffee might lead to an escalation in the area under the curve for the glucose response, an immediate effect. Conversely, long-term studies suggested that caffeinated coffee might contribute to the enhancement of glycaemic metabolism over time by reducing the glucose curve and bolstering the insulin response. Despite the immediate short-term effects, an overall positive long-term impact on glucose metabolism was reported.
Cocoa consumption has strong beneficial impacts on cardiovascular health, reducing blood pressure, improving vascular function, and modulating lipid and glucose metabolism.
2017 Frontiers in Nutrition Cocoa, Blood Pressure, and Vascular Function Ludovici V, Barthelmes J, Nägele MP, Enseleit F, Ferri C, Flammer AJ, et al.
Systematic Review High Blood Pressure Vascular Function
In the study's methodology, the link between the consumption of natural polyphenol-rich foods, specifically cocoa, and a decreased risk of cardiovascular diseases was explored. The process involved evaluating cocoa's influence on various aspects, such as blood pressure reduction, vascular function improvement, lipid and glucose metabolism modulation, and reduction of platelet aggregation. This evaluation was performed in varying demographic groups, including healthy individuals, individuals with risk factors such as diabetes and arterial hypertension, and individuals with established coronary heart diseases or heart failure.
The study's findings indicate that cocoa's consumption has a significant and positive effect on cardiovascular health. Notably, it was found to reduce blood pressure, enhance vascular function, and modulate lipid and glucose metabolism. These beneficial effects were observed in all the subjects irrespective of their health status - healthy, at risk, or with established cardiovascular diseases. The results hypothesize several potential mechanisms through which cocoa exerts these positive effects, including the activation of nitric oxide synthase, increased availability of nitric oxide, and inherent antioxidant and anti-inflammatory properties.
Review Articles
Review articles summarise and critically evaluate the current state of research on a specific topic or field by synthesising multiple primary research studies.
Chinese Herbal Medicine for Type 2 Diabetes Mellitus With Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis
2022 Jun 27 Frontiers in Pharmacology Peng S, Liu L, Xie Z, Zhang X, Xie C, Ye S, et al.
The CHM in combination with WM seems to be more beneficial in T2DM with NAFLD patients in improving lipid and glucose metabolism, liver function, and insulin resistance as well as improving overall efficiency and reducing body weight.
Systematic Review Meta-Analysis Chinese Herbal MedicinePhytochemistry, bioactivities and future prospects of mulberry leaves: A review
2022 Mar Food Chemistry Ma G, Chai X, Hou G, Zhao F, Meng Q
MLs and their extracts may be a promising treatment option for regulating glucose metabolism and lipid metabolism as well as anticancer effects. The dominant compounds responsible for the pharmacological effects of resisting oxidation, reducing blood sugar and lipids, resisting cancer and resisting inflammation in MLs include phenols, flavonoids, polysaccharides and alkaloids. Furthermore, ML suggests ability to inhibit multiple oxidase as well as anti-diabetic effects however more research is needed to yield stronger suggestions
Review Article Sang YeConsumption of sesame seeds and sesame products has favorable effects on blood glucose levels but not on insulin resistance: A systematic review and meta‐analysis of controlled clinical trials
2022 Jan 18 Phytotherapy Research Sohouli MH, Haghshenas N, Hernández‐Ruiz , Shidfar F
Systematic Review Meta-Analysis Blood Sugar SesameConsumption of sesame seeds and its products positively influences human glucose metabolism, potentially making it a beneficial addition to glucose-lowering diets.
The Effect of Acupuncture on Glucose Metabolism and Lipid Profiles in Patients with PCOS: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
2021 Mar 22 Evidence-Based Complementary and Alternative Medicine Ruqun Zheng, Peng Qing, Mei Han, Jinlong Song, Min Hu, Hongxia Ma, et al.
Systematic Review Meta-AnalysisAcupuncture could improve body mass index, waist-to-hip ratio as well as insulin resistance (HOMA-IR) in patients with PCOS.
Impact of soy consumption on human health: integrative review
2020 Jan Brazilian Journal of Food Technology Nogueira-de-Almeida CA, Ferraz IS, Ued FV, Almeida ACF, Ciampo LAD
The integrative review on soy consumption and its effects on human health, based on 97 selected studies, provides insights into various aspects including its impact on protein quality, early exposure using soy formulas, and effects on conditions such as breast cancer, endometrial and ovarian cancer, prostate cancer, cardiovascular disease, glucose metabolism, type 2 diabetes, obesity, reproductive health, menopause, osteoporosis, microbiota, immunity, immunomodulation, thyroid function, attention-deficit hyperactivity disorder, and renal function.
Review Article SoybeanClinical Trials
Clinical trials are research studies that involve people and are conducted to evaluate the safety and efficacy of new treatments or interventions, such as drugs, medical devices, or behavioural therapies.
Study Protocols
Published study protocols are detailed plans that outline the objectives, methodology, statistical analyses, and organisation of a research study that have been made publicly available for others to review and use as a reference.
Presentation Slides
Systematic Review
Consumption of sesame seeds and its products positively influences human glucose metabolism, potentially making it a beneficial addition to glucose-lowering diets.
Sohouli MH, Haghshenas N, Hernández‐Ruiz , Shidfar F
Systematic Review
Acupuncture could improve body mass index, waist-to-hip ratio as well as insulin resistance (HOMA-IR) in patients with PCOS.
Ruqun Zheng, Peng Qing, Mei Han, Jinlong Song, Min Hu, Hongxia Ma, Juan Li
Systematic Review
Coffee consumption, in the long term, improves glucose metabolism but may cause unfavourable acute effects.
Reis CEG, Dórea JG, da Costa THM
Systematic Review
Cocoa consumption has strong beneficial impacts on cardiovascular health, reducing blood pressure, improving vascular function, and modulating lipid and glucose metabolism.
Ludovici V, Barthelmes J, Nägele MP, Enseleit F, Ferri C, Flammer AJ, Ruschitzka F, Sudano I
Executive Summary
Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Glucose Metabolism" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.
Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Glucose Metabolism" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.
Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Glucose Metabolism" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.
A Systematic Review published in 2022 in the journal Phytotherapy Research found that Consumption of sesame seeds and its products positively influences human glucose metabolism, potentially making it a beneficial addition to glucose-lowering diets. The methodology involved conducting a systematic review and meta-analysis on the effect of sesame seeds consumption on blood glucose and insulin resistance in adults. The researchers gathered data from recognized academic resources like PubMed/MEDLINE, SCOPUS, Web of Science, Google Scholar, and EMBASE, which included controlled clinical trials up until February 2021. The sesame products in these trials ranged from sesame oil, sesamin, and tahini, with the intervention period lasting from 45 days to 9 weeks. The results illustrate that the intake of sesame and its products significantly improved fasting blood glucose and Hemoglobin A1c levels. Nonetheless, the results regarding fasting serum insulin and the homeostatic model assessment for insulin resistance were not found to have any significant relation. Hence, the consumption of sesame might be a beneficial supplement for managing glucose levels in humans.
A Systematic Review published in 2021 in the journal Evidence-Based Complementary and Alternative Medicine found that Acupuncture could improve body mass index, waist-to-hip ratio as well as insulin resistance (HOMA-IR) in patients with PCOS. Overall, we found that acupuncture was closely associated with decreased BMI, WHR, FPG, and HOMA-IR and that acupuncture could significantly improve HOMA-IR and the level of fasting glucose in patients with PCOS, which confirms previous reports. It is also reported that acupuncture can decrease BMI and WHR. FINS, 2hFPG, and 2hFINS were reduced in the acupuncture groups, but these differences were not significantly different. The results of the lipid profile were reported in a few studies, and we found that acupuncture significantly improved triglycerides levels, while the differences in total cholesterol, LDL-C, and HDL-C were not significant. Acupuncture seems to be associated with a few adverse events, and the reported adverse events, such as bleeding, were mild and transient, demonstrating that acupuncture is safe and reliable. Thus, we conclude that acupuncture, compared with standard therapy, is more effective and safer in improving glucose metabolism and insulin sensitivity in patients with PCOS.
A Systematic Review published in 2019 in the journal Journal of Traditional and Complementary Medicine found that Coffee consumption, in the long term, improves glucose metabolism but may cause unfavourable acute effects. Researchers undertook a systematic review to evaluate the impact of coffee consumption on glucose metabolism. They scanned two electronic databases, PubMed and Web of Science, for relevant studies published till September 2017. After thorough scrutiny, eight clinical trials involving 247 participants were earmarked for analysis. These trials were divided into short-term (1-3 hours) and long-term (2-16 weeks) studies for distinct evaluation. The participants' characteristics, major discoveries, and study quality were all meticulously noted and analysed. The initial short-term studies revealed that consumption of caffeinated coffee might lead to an escalation in the area under the curve for the glucose response, an immediate effect. Conversely, long-term studies suggested that caffeinated coffee might contribute to the enhancement of glycaemic metabolism over time by reducing the glucose curve and bolstering the insulin response. Despite the immediate short-term effects, an overall positive long-term impact on glucose metabolism was reported.
A Systematic Review published in 2017 in the journal Frontiers in Nutrition found that Cocoa consumption has strong beneficial impacts on cardiovascular health, reducing blood pressure, improving vascular function, and modulating lipid and glucose metabolism. In the study's methodology, the link between the consumption of natural polyphenol-rich foods, specifically cocoa, and a decreased risk of cardiovascular diseases was explored. The process involved evaluating cocoa's influence on various aspects, such as blood pressure reduction, vascular function improvement, lipid and glucose metabolism modulation, and reduction of platelet aggregation. This evaluation was performed in varying demographic groups, including healthy individuals, individuals with risk factors such as diabetes and arterial hypertension, and individuals with established coronary heart diseases or heart failure. The study's findings indicate that cocoa's consumption has a significant and positive effect on cardiovascular health. Notably, it was found to reduce blood pressure, enhance vascular function, and modulate lipid and glucose metabolism. These beneficial effects were observed in all the subjects irrespective of their health status - healthy, at risk, or with established cardiovascular diseases. The results hypothesize several potential mechanisms through which cocoa exerts these positive effects, including the activation of nitric oxide synthase, increased availability of nitric oxide, and inherent antioxidant and anti-inflammatory properties.
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This study used pH-modified tap water in the participants' homes and no difference in gut microbiota or glucose metabolism was found. —Jinnan C 28 Dec 2023