Immune-Modulating
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Curcumin, a component of Indian spice turmeric, presents a potential natural treatment for depression, influencing neurotransmitters and protecting against several biological systems compromised in depression.
Anti-Inflammatory Immune-Modulating Immunomodulation
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Research Articles
Published research studies are articles that present the findings of original research that has undergone a peer-review process and has been made publicly available in scholarly journals, books or other media.
Integrated metabolomics and network pharmacology approach to reveal immunomodulatory mechanisms of Yupingfeng granules
2021 Feb Journal of Pharmaceutical and Biomedical Analysis Li M, Gao Y, Yue X, Zhang B, Zhou H, Yuan C, et al.
YPFG influences the metabolism of bile acids and phospholipids. Flavonoids and saponins in YPFG were the main active components responsible for its immune-modulating effects. These components improved bile acid metabolism by enhancing the expression of certain proteins.
Network Pharmacology ImmunomodulationMultiple antidepressant potential modes of action of curcumin: a review of its anti-inflammatory, monoaminergic, antioxidant, immune-modulating and neuroprotective effects
2012 Oct 03 Journal of Psychopharmacology Lopresti AL, Hood SD, Drummond PD
Review Article Immunomodulation Immune-Modulating Anti-Inflammatory Turmeric NeuroprotectiveCurcumin, a component of Indian spice turmeric, presents a potential natural treatment for depression, influencing neurotransmitters and protecting against several biological systems compromised in depression.
Research Insights
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Curcumin, a component of Indian spice turmeric, presents a potential natural treatment for depression, influencing neurotransmitters and protecting against several biological systems compromised in depression.
2012 Journal of Psychopharmacology Multiple antidepressant potential modes of action of curcumin: a review of its anti-inflammatory, monoaminergic, antioxidant, immune-modulating and neuroprotective effects Lopresti AL, Hood SD, Drummond PD
Review Article Anti-Inflammatory Immunomodulation Neuroprotective
The research methodology involved an extensive review of the varying influences and effects of curcumin on systems implicated in depression. These included neurotransmitter systems like serotonin and dopamine which are critical to mood regulation. The study also explored the effects of curcumin on hypothalamus-pituitary-adrenal disturbances, famously associated with stress response and mood disorders.
In terms of results, curcumin demonstrated promising potential as an antidepressant in animal models of depression. Additionally, it was found to help moderate damage to neurological systems and intestinal permeability, both of which are often compromised in major depressive disorders. It also exhibited properties that could help lower inflammation and protect against oxidative stress and mitochondrial damage. Together, these findings position curcumin as a promising natural treatment for depression.
Review Articles
Review articles summarise and critically evaluate the current state of research on a specific topic or field by synthesising multiple primary research studies.
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Curcumin, a component of Indian spice turmeric, presents a potential natural treatment for depression, influencing neurotransmitters and protecting against several biological systems compromised in depression.
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