Menthol
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Peppermint as a promising treatment agent in inflammatory conditions: A comprehensive systematic review of literature
2023 Oct 18 Phytotherapy Research Goudarzi MA, Radfar M, Goudarzi Z
Systematic ReviewPeppermint, particularly its component menthol, has been indicated to possess anti-inflammatory properties, potentially improving management of chronic disorders like diabetes and cancer.
Toxicological effects ofMentha x piperita(peppermint): a review
2019 Aug 07 Toxin Reviews Malekmohammad K, Rafieian-Kopaei M, Sardari S, Sewell RDE
The study concludes that peppermint and its main constituents, while not possessing major innate mutagenic, genotoxic, or embryotoxic properties, are moderately toxic, and caution is advised in individuals with bile duct obstruction, gall bladder inflammation, gastrointestinal reflux, or hiatus hernia.
Review Article Peppermint Menthol ToxicityResearch Insights
Insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.
Peppermint, particularly its component menthol, has been indicated to possess anti-inflammatory properties, potentially improving management of chronic disorders like diabetes and cancer.
2023 Phytotherapy Research Peppermint as a promising treatment agent in inflammatory conditions: A comprehensive systematic review of literature Goudarzi MA, Radfar M, Goudarzi Z
Systematic Review
Researchers searched four databases (Web of Sciences, PubMed, Scopus, and Embase) to identify articles relevant to peppermint and its anti-inflammatory effects. The search, conducted up to March 2023, led to the screening of 3805 records. From these, 14 articles were selected that met the study requirements. This extensive search and selection process aimed to cover as broad a range of reputable sources as possible, providing a holistic view of existing research on peppermint's potential anti-inflammatory capabilities.
In these studies, peppermint showed potential as an anti-inflammatory agent. Its hypothetical mechanism of action includes the activation of the AMP-activated protein kinase/unc-51 like kinase 1/nuclear factor-E2 associated factor 2 autophagy pathway. Concurrently, it might downregulate extracellular signal-regulated kinase-nuclear factor kappa B and mitogen-activated protein kinases pathways, thereby enabling inflammation suppression. Other likely pathways include attenuating oxidative stress and inhibiting the production of pro-inflammatory mediators and nitric oxide. Additionally, it may induce the production of anti-inflammatory prostaglandins. These combined pathways potentially lead to the overall reduction of inflammation. However, more human studies are required to confirm these beneficial effects.
Review Articles
Review articles summarise and critically evaluate the current state of research on a specific topic or field by synthesising multiple primary research studies.
Peppermint as a promising treatment agent in inflammatory conditions: A comprehensive systematic review of literature
2023 Oct 18 Phytotherapy Research Goudarzi MA, Radfar M, Goudarzi Z
Systematic ReviewPeppermint, particularly its component menthol, has been indicated to possess anti-inflammatory properties, potentially improving management of chronic disorders like diabetes and cancer.
Toxicological effects ofMentha x piperita(peppermint): a review
2019 Aug 07 Toxin Reviews Malekmohammad K, Rafieian-Kopaei M, Sardari S, Sewell RDE
The study concludes that peppermint and its main constituents, while not possessing major innate mutagenic, genotoxic, or embryotoxic properties, are moderately toxic, and caution is advised in individuals with bile duct obstruction, gall bladder inflammation, gastrointestinal reflux, or hiatus hernia.
Review Article Peppermint Menthol ToxicityClinical Trials
Clinical trials are research studies that involve people and are conducted to evaluate the safety and efficacy of new treatments or interventions, such as drugs, medical devices, or behavioural therapies.
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Systematic Review
Peppermint, particularly its component menthol, has been indicated to possess anti-inflammatory properties, potentially improving management of chronic disorders like diabetes and cancer.
Goudarzi MA, Radfar M, Goudarzi Z
Executive Summary
Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Menthol" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.
Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Menthol" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.
Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Menthol" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.
A Systematic Review published in 2023 in the journal Phytotherapy Research found that Peppermint, particularly its component menthol, has been indicated to possess anti-inflammatory properties, potentially improving management of chronic disorders like diabetes and cancer. Researchers searched four databases (Web of Sciences, PubMed, Scopus, and Embase) to identify articles relevant to peppermint and its anti-inflammatory effects. The search, conducted up to March 2023, led to the screening of 3805 records. From these, 14 articles were selected that met the study requirements. This extensive search and selection process aimed to cover as broad a range of reputable sources as possible, providing a holistic view of existing research on peppermint's potential anti-inflammatory capabilities. In these studies, peppermint showed potential as an anti-inflammatory agent. Its hypothetical mechanism of action includes the activation of the AMP-activated protein kinase/unc-51 like kinase 1/nuclear factor-E2 associated factor 2 autophagy pathway. Concurrently, it might downregulate extracellular signal-regulated kinase-nuclear factor kappa B and mitogen-activated protein kinases pathways, thereby enabling inflammation suppression. Other likely pathways include attenuating oxidative stress and inhibiting the production of pro-inflammatory mediators and nitric oxide. Additionally, it may induce the production of anti-inflammatory prostaglandins. These combined pathways potentially lead to the overall reduction of inflammation. However, more human studies are required to confirm these beneficial effects.
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