Sulphate
Recent Insights
Hépar mineral water, rich in sulphates and magnesium, effectively treats functional constipation, showing significant results within 7 days.
Constipation Magnesium Mineral Water
Drinking natural mineral water rich in magnesium sulphate and sodium sulphate daily improves bowel movement frequency and stool consistency in people with functional constipation.
Constipation Magnesium Mineral Water
Related Topics
Research Articles
Published research studies are articles that present the findings of original research that has undergone a peer-review process and has been made publicly available in scholarly journals, books or other media.
How to submit an article:
- Registered users can submit any published journal article that has a unique DOI (Digital Object Identifier) name or link to Research Hub.
- For example, you can paste the full DOI link:
https://doi.org/10.1109/5.771073
or just the DOI name:10.1109/5.771073
into the field above and click submit. - The person who is first to submit a valid article to Research Hub will forever be credited for it, and every article submission earns you +6 Research Points.
Natural Mineral Waters and Metabolic Syndrome: Insights From Obese Male and Female C57BL/6 Mice on Caloric Restriction
2022 May 24 Frontiers in Nutrition Narciso L, Martinelli A, Torriani F, Frassanito P, Bernardini R, Chiarotti F, et al.
Animal Study Metabolic Syndrome Mineral Water Cholesterol Blood SugarCertain natural mineral waters, when combined with a low-calorie diet, effectively reduce cholesterol and glucose levels in mice with metabolic syndrome.
Time to treatment response of a magnesium- and sulphate-rich natural mineral water in functional constipation
2019 Sep Nutrition Dupont C, Constant F, Imbert A, Hébert G, Zourabichvili O, Kapel N
Clinical Study Randomised Controlled Trial Constipation Magnesium Mineral Water SulphateHépar mineral water, rich in sulphates and magnesium, effectively treats functional constipation, showing significant results within 7 days.
Efficacy and safety of a natural mineral water rich in magnesium and sulphate for bowel function: a double-blind, randomized, placebo-controlled study
2015 Nov 18 European Journal of Nutrition Bothe G, Coh A, Auinger A
Randomised Controlled Trial Sulphate Mineral Water Magnesium ConstipationDrinking natural mineral water rich in magnesium sulphate and sodium sulphate daily improves bowel movement frequency and stool consistency in people with functional constipation.
Research Insights
Insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.
Certain natural mineral waters, when combined with a low-calorie diet, effectively reduce cholesterol and glucose levels in mice with metabolic syndrome.
2022 Frontiers in Nutrition Natural Mineral Waters and Metabolic Syndrome: Insights From Obese Male and Female C57BL/6 Mice on Caloric Restriction Narciso L, Martinelli A, Torriani F, Frassanito P, Bernardini R, Chiarotti F, et al.
Animal Study Blood Sugar Cholesterol Metabolic Syndrome
The study involved 125 male and female C57BL/6 mice. Ten mice were kept as a healthy control group, fed a standard diet with tap water. The remaining 115 mice were fed a high-calorie diet (60% fat, 10% fructose in water) for four months to induce metabolic syndrome, followed by a two-month treatment phase with a low-calorie diet and various types of natural mineral water (NMW). The mice were divided into six treatment groups, each receiving a different NMW, and a control group receiving tap water. The study monitored body weight and blood biochemistry over six months.
After four months on a high-calorie diet, both male and female mice developed obesity, high cholesterol, and high blood sugar, with males showing greater increases. During the treatment phase, NMWs rich in sulphate, magnesium, bicarbonate, and minimally mineralized water, along with a low-calorie diet, significantly lowered total cholesterol, HDL cholesterol, and glucose levels. Sex differences were observed during both the induction and treatment phases. These findings indicate that specific NMWs, in conjunction with a low-calorie diet, may help manage blood lipid and glucose levels in metabolic syndrome, although further research is needed to confirm these results in humans.
Hépar mineral water, rich in sulphates and magnesium, effectively treats functional constipation, showing significant results within 7 days.
2019 Nutrition Time to treatment response of a magnesium- and sulphate-rich natural mineral water in functional constipation Dupont C, Constant F, Imbert A, Hébert G, Zourabichvili O, Kapel N
Clinical Study Constipation Magnesium Mineral Water
In this multicenter, randomized, double-blind, controlled study, 226 outpatients with functional constipation were evaluated. Participants underwent a washout period before consuming 1.5 liters of water daily for 14 days, of which 1 liter was either Hépar or low-mineral water. Patients self-reported stool consistency daily, and an expert investigator, blinded to the treatment groups, evaluated stool consistency using the Bristol stool scale based on patient-provided photographs.
The study successfully met its primary endpoint, with 50% of participants in the Hépar group responding to treatment by day 14, compared to 29% in the control group. The average time to observe a treatment response was 6.4 days for Hépar users, shorter than the 7.3 days in the control group. Approximately 60% of patients provided stool scores, with 79% of these scores closely aligning between patients and experts. The safety analysis of Hépar indicated excellent results, confirming its efficacy and safety in treating functional constipation.
Drinking natural mineral water rich in magnesium sulphate and sodium sulphate daily improves bowel movement frequency and stool consistency in people with functional constipation.
2015 European Journal of Nutrition Efficacy and safety of a natural mineral water rich in magnesium and sulphate for bowel function: a double-blind, randomized, placebo-controlled study Bothe G, Coh A, Auinger A
Randomised Controlled Trial Constipation Magnesium Mineral Water
This placebo-controlled, double-blind, randomized trial involved 106 healthy individuals with functional constipation. They were randomly assigned to consume either 300 or 500 ml of a natural mineral water rich in magnesium sulphate and sodium sulphate (Donat Mg) or a placebo water daily for six weeks. The 300-ml groups were discontinued following an interim analysis. Participants recorded their bowel movements, stool consistency, gastrointestinal symptoms, and general well-being in a diary. The primary outcome was the change in the number of complete spontaneous bowel movements per week.
In the 500-ml group, consisting of 75 subjects, there was a tendency for a higher increase in complete spontaneous bowel movements per week in the active group compared to the placebo after six weeks. The mean number of spontaneous bowel movements significantly increased over the study period, with notable differences between the study arms throughout the study. Stool consistency and subjectively perceived symptoms of constipation improved significantly with the mineral water compared to placebo. Overall, the daily consumption of this specific mineral water led to improvements in bowel movement frequency and stool consistency, enhancing the health-related quality of life for participants with functional constipation.
Review Articles
Review articles summarise and critically evaluate the current state of research on a specific topic or field by synthesising multiple primary research studies.
Clinical Trials
Clinical trials are research studies that involve people and are conducted to evaluate the safety and efficacy of new treatments or interventions, such as drugs, medical devices, or behavioural therapies.
Time to treatment response of a magnesium- and sulphate-rich natural mineral water in functional constipation
2019 Sep Nutrition Dupont C, Constant F, Imbert A, Hébert G, Zourabichvili O, Kapel N
Clinical Study Randomised Controlled Trial Constipation Magnesium Mineral Water SulphateHépar mineral water, rich in sulphates and magnesium, effectively treats functional constipation, showing significant results within 7 days.
Efficacy and safety of a natural mineral water rich in magnesium and sulphate for bowel function: a double-blind, randomized, placebo-controlled study
2015 Nov 18 European Journal of Nutrition Bothe G, Coh A, Auinger A
Randomised Controlled Trial Sulphate Mineral Water Magnesium ConstipationDrinking natural mineral water rich in magnesium sulphate and sodium sulphate daily improves bowel movement frequency and stool consistency in people with functional constipation.
Study Protocols
Published study protocols are detailed plans that outline the objectives, methodology, statistical analyses, and organisation of a research study that have been made publicly available for others to review and use as a reference.
Presentation Slides
Animal Study
Certain natural mineral waters, when combined with a low-calorie diet, effectively reduce cholesterol and glucose levels in mice with metabolic syndrome.
Narciso L, Martinelli A, Torriani F, Frassanito P, Bernardini R, Chiarotti F, Marianelli C
Clinical Study
Hépar mineral water, rich in sulphates and magnesium, effectively treats functional constipation, showing significant results within 7 days.
Dupont C, Constant F, Imbert A, Hébert G, Zourabichvili O, Kapel N
Randomised Controlled Trial
Drinking natural mineral water rich in magnesium sulphate and sodium sulphate daily improves bowel movement frequency and stool consistency in people with functional constipation.
Bothe G, Coh A, Auinger A
Executive Summary
Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Sulphate" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.
Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Sulphate" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.
Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Sulphate" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.
A Animal Study published in 2022 in the journal Frontiers in Nutrition found that Certain natural mineral waters, when combined with a low-calorie diet, effectively reduce cholesterol and glucose levels in mice with metabolic syndrome. The study involved 125 male and female C57BL/6 mice. Ten mice were kept as a healthy control group, fed a standard diet with tap water. The remaining 115 mice were fed a high-calorie diet (60% fat, 10% fructose in water) for four months to induce metabolic syndrome, followed by a two-month treatment phase with a low-calorie diet and various types of natural mineral water (NMW). The mice were divided into six treatment groups, each receiving a different NMW, and a control group receiving tap water. The study monitored body weight and blood biochemistry over six months. After four months on a high-calorie diet, both male and female mice developed obesity, high cholesterol, and high blood sugar, with males showing greater increases. During the treatment phase, NMWs rich in sulphate, magnesium, bicarbonate, and minimally mineralized water, along with a low-calorie diet, significantly lowered total cholesterol, HDL cholesterol, and glucose levels. Sex differences were observed during both the induction and treatment phases. These findings indicate that specific NMWs, in conjunction with a low-calorie diet, may help manage blood lipid and glucose levels in metabolic syndrome, although further research is needed to confirm these results in humans.
A Clinical Study published in 2019 in the journal Nutrition found that Hépar mineral water, rich in sulphates and magnesium, effectively treats functional constipation, showing significant results within 7 days. In this multicenter, randomized, double-blind, controlled study, 226 outpatients with functional constipation were evaluated. Participants underwent a washout period before consuming 1.5 liters of water daily for 14 days, of which 1 liter was either Hépar or low-mineral water. Patients self-reported stool consistency daily, and an expert investigator, blinded to the treatment groups, evaluated stool consistency using the Bristol stool scale based on patient-provided photographs. The study successfully met its primary endpoint, with 50% of participants in the Hépar group responding to treatment by day 14, compared to 29% in the control group. The average time to observe a treatment response was 6.4 days for Hépar users, shorter than the 7.3 days in the control group. Approximately 60% of patients provided stool scores, with 79% of these scores closely aligning between patients and experts. The safety analysis of Hépar indicated excellent results, confirming its efficacy and safety in treating functional constipation.
A Randomised Controlled Trial published in 2015 in the journal European Journal of Nutrition found that Drinking natural mineral water rich in magnesium sulphate and sodium sulphate daily improves bowel movement frequency and stool consistency in people with functional constipation. This placebo-controlled, double-blind, randomized trial involved 106 healthy individuals with functional constipation. They were randomly assigned to consume either 300 or 500 ml of a natural mineral water rich in magnesium sulphate and sodium sulphate (Donat Mg) or a placebo water daily for six weeks. The 300-ml groups were discontinued following an interim analysis. Participants recorded their bowel movements, stool consistency, gastrointestinal symptoms, and general well-being in a diary. The primary outcome was the change in the number of complete spontaneous bowel movements per week. In the 500-ml group, consisting of 75 subjects, there was a tendency for a higher increase in complete spontaneous bowel movements per week in the active group compared to the placebo after six weeks. The mean number of spontaneous bowel movements significantly increased over the study period, with notable differences between the study arms throughout the study. Stool consistency and subjectively perceived symptoms of constipation improved significantly with the mineral water compared to placebo. Overall, the daily consumption of this specific mineral water led to improvements in bowel movement frequency and stool consistency, enhancing the health-related quality of life for participants with functional constipation.
Moderation Tools
Topic
Sign In
Users not signed in are limited to viewing the 5 most recent items of content.