Endothelial Dysfunction

Presentation Slides

Chinese Medicine Research Hub

Meta-Analysis

The study reveals that pomegranate juice does not significantly affect vascular adhesion factors, but can effectively reduce the inflammatory marker, interleukin-6.

2021 Phytomedicine Effect of pomegranate juice on vascular adhesion factors: A systematic review and meta-analysis
Asgary S, Karimi R, Joshi T, Kilpatrick KL, Moradi S, Samimi Z, Mohammadi E, Farzaei MH, Bishayee A

Chinese Medicine Research Hub

Review Article

Honey, with its variable composition based on botanical origin, exhibits antioxidant and anti-inflammatory properties, suggesting its potential efficacy in managing obesity-related dysfunctions, including neurodegeneration, through improved glycemic control and lipid profile.

2020 The Journal of Nutritional Biochemistry Honey and obesity-related dysfunctions: a summary on health benefits
Terzo S, Mulè F, Amato A

Chinese Medicine Research Hub

Meta-Analysis

Pomegranate juice supplementation notably diminishes inflammation and vascular dysfunction markers in adults, offering potential cardiovascular health benefits.

2020 Complementary Therapies in Medicine The effects of pomegranate supplementation on biomarkers of inflammation and endothelial dysfunction: A meta-analysis and systematic review
Wang P, Zhang Q, Hou H, Liu Z, Wang L, Rasekhmagham R, Kord-Varkaneh H, Santos HO, Yao G

Executive Summary

Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Endothelial Dysfunction" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.

Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Endothelial Dysfunction" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.

Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Endothelial Dysfunction" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.

A Meta-Analysis published in 2021 in the journal Phytomedicine found that The study reveals that pomegranate juice does not significantly affect vascular adhesion factors, but can effectively reduce the inflammatory marker, interleukin-6. In order to evaluate the role of pomegranate in endothelial dysfunction, databases including PubMed, Scopus, Web of Science, Cochrane, and Google Scholar were utilized up until July 2020. Relevant studies were chosen that examined pomegranate's impacts on vascular adhesion factors, namely intercellular adhesion molecule 1, vascular cell adhesion molecule 1, E-selectin, and interleukin-6. Computational tools were used to analyse this large data set. The results demonstrated that human studies showed no significant effects of pomegranate juice on intercellular adhesion molecule 1, vascular cell adhesion molecule 1, and E-selectin compared to the control group. However, results revealed that pomegranate juice could significantly lower interleukin-6. Despite the absence of significant impacts on vascular adhesion factors, the notable reduction of interleukin-6 suggests the potential of pomegranate juice in treating endothelial dysfunction-related conditions such as cardiovascular diseases.

A Review Article published in 2020 in the journal The Journal of Nutritional Biochemistry found that Honey, with its variable composition based on botanical origin, exhibits antioxidant and anti-inflammatory properties, suggesting its potential efficacy in managing obesity-related dysfunctions, including neurodegeneration, through improved glycemic control and lipid profile. The review explores honey's therapeutic potential, emphasizing its diverse bioactive compounds. The focus is on its effects in combating obesity-related dysfunctions, supported by experimental evidence from animal studies. Experimental findings indicate that honey can enhance glycemic control and lipid profile, offering protection against endothelial dysfunction and neurodegeneration in obesity. The role of honey's key constituents, particularly polyphenols, is highlighted, underscoring the need for further human studies to confirm these health benefits.

A Meta-Analysis published in 2020 in the journal Complementary Therapies in Medicine found that Pomegranate juice supplementation notably diminishes inflammation and vascular dysfunction markers in adults, offering potential cardiovascular health benefits. The research used a broad approach, systematically reviewing and performing a meta-analysis of 16 randomised controlled trials including 572 participants, as per the Preferred Items for Reporting of Systematic Reviews and Meta-Analyses guidelines. Relevant articles and references were found via the PubMed/Medline and SCOPUS databases, with screening carried out up until May 2019. The studies explored the impact of pomegranate juice supplements. The discussion reveals that pomegranate supplementation conspicuously reduced the levels of certain pro-inflammatory and vascular dysfunction markers. However, the research found no significant reduction in some other markers when compared to a placebo. Despite not all markers recording significant reduction, the overall findings strongly suggest pomegranate supplements as a viable tactic for reducing inflammation in adults, potentially offering cardiovascular health advantages.

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