Children's Health
Also known as: Pediatric
Sub-Topics:
Recent Insights
Honey potentially has superior results than cough medication or placebo in curtailing symptoms and enhancing sleep in children with acute cough.
Children's Health Cough Sleep
The combination of Tuina (Chinese therapeutic massage) and Shen Ling Bai Zhu San is more effective in treating pediatric diarrhea due to spleen deficiency than Shen Ling Bai Zhu San alone.
Children's Health Diarrhoea Meridian Massage
Honey is effective in treating coughs in children above 12 months.
Children's Health
Parent-administered pediatric tuina is effective at reducing core symptoms of ADHD in preschool children and improves child appetite and sleep quality.
ADHD Appetite Children's Health
Consumption of pumpkin seeds enhances the nutritional status and improves the attention deficit of deaf female children exhibiting ADHD symptoms.
ADHD Children's Health Iron
Allergic rhinitis in children, according to traditional Chinese medicine, is interrelated with the functionality of lungs, spleen, and kidney and can be treated with combined Western and Chinese herbal medicines.
Children's Health Hay Fever
Related Topics
Research Articles
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Honey for acute cough in children — a systematic review
2023 Jun 25 European Journal of Pediatrics Kuitunen I, Renko M
Systematic Review Sleep Children's Health CoughHoney potentially has superior results than cough medication or placebo in curtailing symptoms and enhancing sleep in children with acute cough.
Omega-3 supplements in the prevention and treatment of youth depression and anxiety symptoms: A scoping review
2023 Apr 20 PLOS One Reily NM, Tang S, Negrone A, Gan DZQ, Sheanoda V, Christensen H
Review Article Depression Omega-3 Fatty Acids Children's Health AnxietyEffect of low-level laser stimulation of acupuncture points in pediatric dentistry: a systematic review
2023 Jan 24 Lasers in Medical Science Mira PCS, Vilela LD, Corona SAM, Borsatto MC
The LLLT at acupuncture points is associated with positive results on sleep bruxism, preanesthetic pain, and gag reflex in pediatric dentistry.
Systematic Review Children's HealthSafety and Acceptance of Acupuncture and Acupressure in Children, Adolescents, and Young Adults Undergoing Hematopoietic Stem Cell Transplant
2022 Dec 01 Cancer Nursing Bettini E, Idiokitas R, Mahmood L, Jacobs S, Steinhorn D
This study demonstrates that acupuncture and acupressure are well accepted by children and their families admitted for hematopoietic stem cell transplant (HSCT) and are safe even when performed in the first 4 weeks following transplant when the patient is likely to have thrombocytopenia.
Cohort Study Children's HealthParent-administered pediatric tuina for the treatment of attention deficit hyperactivity disorder symptoms: Process evaluation of a pilot randomized controlled trial
2022 Nov Complementary Therapies in Medicine Chen SC, Cheng HL, Han LF, Wu GT, Zhang RY, Suen LKP, et al.
Implementation of parent-administered pediatric tuina intervention is feasible and acceptable. The intervention can be refined by improving the TCM pattern identification procedure and adjusting outcome settings in a fully powered study in the future.
Randomised Controlled Trial Children's HealthResearch Insights
Insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.
Honey potentially has superior results than cough medication or placebo in curtailing symptoms and enhancing sleep in children with acute cough.
2023 European Journal of Pediatrics Honey for acute cough in children — a systematic review Kuitunen I, Renko M
Systematic Review Cough Sleep
Methodology:
This targeted review leveraged multiple databases, such as PubMed, Scopus, CENTRAL, CINAHL, and Web of Science, to extract relevant trials relating to honey's usage in treating acute child cough. By applying a systematic approach, the emphasis was on randomized controlled trials featuring children. To ensure the results' credibility, payment was done for risk-of-bias as well as the quality of the evidence. The studies were not combined owing to the absence of essential information; instead, conclusions provided a range of noticed effects for principal results.
Discussion of results:
Following rigorous screening of almost four hundred papers, a select ten were incorporated. Significant variability in biases was noticed, with two studies possessing a high risk-of-bias and six inviting some concerns. The evidence, though of low to very low quality, indicated honey's potential superiority over placebo/no treatment and cough medication, both in reducing cough frequency and improving sleep quality.
Honey is effective in treating coughs in children above 12 months.
2022 Cureus Journal of Medical Science Comparing the Effectiveness of Honey Consumption With Anti-Cough Medication in Pediatric Patients: A Systematic Review Mashat GD, Hazique M, Khan KI, Ramesh P, Kanagalingam S, Ul Haq Z, et al.
Systematic Review
The researchers undertook a systematic review of literature across five databases, using a Medical Subject Heading strategy, keywords, and defined inclusion and exclusion criteria to identify relevant studies. This review incorporated a range of study types, including systematic reviews, meta-analyses, randomized controlled trials, observational studies and cross-sectional studies. Those articles without a clear methodology section were excluded. The quality of the remaining literature was appraised using a specific checklist.
Following the review, it was found that honey is effective in treating coughs in children older than 12 months. Cold and cough medications were also found to be safe, if given at therapeutic doses. However, a note of caution was highlighted for the use of these medications in children under two years, as fatalities have been recorded in some cases; although further studies are recommended to establish a clear safety profile.
Parent-administered pediatric tuina is effective at reducing core symptoms of ADHD in preschool children and improves child appetite and sleep quality.
2022 Phytomedicine Parent-administered pediatric Tuina for attention deficit/hyperactivity disorder symptoms in preschool children: A pilot randomized controlled trial embedded with a process evaluation Chen SC, Yu J, Wang HS, Wang DD, Sun Y, Cheng HL, et al.
Randomised Controlled Trial ADHD Appetite Meridian Massage
This research involved a two-arm, parallel, open-label, pilot Randomized Controlled Trial, where 64 participants were assigned to two separate groups. Parents in the first group attended an online course teaching them pediatric tuina for ADHD, which they would then apply to their children at home. The second group of parents went through online training about a progressive muscle relaxation exercise and engaged in interactive physical activities with their children at home. Both groups carried out their respective interventions every other day for two month, each session lasting at least 20 minutes. The project measured the rate of recruitment, consent, participant adherence, retention and any adverse events.
Upon investigation, both groups demonstrated improvements, with moderate effect size within each group. This was reflected in improvements in core hyperactivity and impulsivity symptoms. Parents also noticed positive changes in their children’s eating habits, sleep quality, and overall parent-child relationship. No serious issues were reported in relation to implementing the parent-administered pediatric tuina or from the interactive physical activity sessions.
The combination of Tuina (Chinese therapeutic massage) and Shen Ling Bai Zhu San is more effective in treating pediatric diarrhea due to spleen deficiency than Shen Ling Bai Zhu San alone.
2022 Journal of Acupuncture and Tuina Science Clinical study on Tuina plus Shen Ling Bai Zhu San in treating children with diarrhea due to spleen deficiency Li J
Clinical Study Diarrhoea Meridian Massage Shen Ling Bai Zhu San
Methodology: The paper reports on a clinical trial involving a total of 105 children diagnosed with diarrhea due to spleen deficiency. These children were randomly allocated into two separate groups: a control group and an observation group. The control group, consisting of 52 children, were exclusively treated with Shen Ling Bai Zhu San orally. The observation group, on the other hand, consisted of 53 children who received an additional Tuina treatment along with Shen Ling Bai Zhu San.
Results: After implementing the treatments, it was found that every child in the observation group showed improvement, compared to 90% improvement rate in the control group. This correlated to a decrease in scores of primary and secondary symptoms of traditional Chinese medicine in both groups post-treatment. Furthermore, the children in the observation group who received both treatments had even lower symptom scores than the control group who only received Shen Ling Bai Zhu San. The treatments were also well-tolerated with no significant adverse reactions reported.
Consumption of pumpkin seeds enhances the nutritional status and improves the attention deficit of deaf female children exhibiting ADHD symptoms.
2021 African Journal of Biological Sciences Improvement of attention deficit hyperactive disorder for deaf female children by intake pumpkin seeds Ataya H
Clinical Study ADHD Iron Magnesium
This study investigated 40 deaf female children, aged between 10 and 12 years, who exhibited symptoms of attention-deficit hyperactivity disorder (ADHD). These children were selected from El Amal school for the deaf and divided into two groups; control and experimental. Various data were gathered on personal and socio-economic factors, food habits, diet history, and clinical signs, along with performing the Attention Deficit Disorder Connected with Hyperactivity for Deaf Children test. The experimental group underwent a dietary intervention, consuming 50g of magnesium and iron-rich pumpkin seeds daily over three months.
The results indicated an improvement in both iron and magnesium levels within the experimental group following the dietary intervention. Notably, compared to the control group, the levels of magnesium and iron were significantly higher in the experimental group after introducing pumpkin seeds into their diet. Furthermore, on evaluating the ADHD symptoms via the Attention Deficit Disorder Connected with Hyperactivity for Deaf Children test, the experimental group showed a more substantial improvement after dietary intervention than the control group. Over time, the findings demonstrated the potential beneficial effects of consuming pumpkin seeds on the nutritional status and ADHD symptoms in the studied population.
Review Articles
Review articles summarise and critically evaluate the current state of research on a specific topic or field by synthesising multiple primary research studies.
Honey for acute cough in children — a systematic review
2023 Jun 25 European Journal of Pediatrics Kuitunen I, Renko M
Systematic Review Sleep Children's Health CoughHoney potentially has superior results than cough medication or placebo in curtailing symptoms and enhancing sleep in children with acute cough.
Omega-3 supplements in the prevention and treatment of youth depression and anxiety symptoms: A scoping review
2023 Apr 20 PLOS One Reily NM, Tang S, Negrone A, Gan DZQ, Sheanoda V, Christensen H
Review Article Depression Omega-3 Fatty Acids Children's Health AnxietyThe scientific evidence for efficacy of omega-3 supplementation in reducing symptoms of depression and anxiety in young people is inconclusive, however, it was found that most "grey literature" sources recommended the use of omega-3 supplements in young people. —Jinnan C 20 Oct 2023
Effect of low-level laser stimulation of acupuncture points in pediatric dentistry: a systematic review
2023 Jan 24 Lasers in Medical Science Mira PCS, Vilela LD, Corona SAM, Borsatto MC
The LLLT at acupuncture points is associated with positive results on sleep bruxism, preanesthetic pain, and gag reflex in pediatric dentistry.
Systematic Review Children's HealthComparing the Effectiveness of Honey Consumption With Anti-Cough Medication in Pediatric Patients: A Systematic Review
2022 Sep 20 Cureus Journal of Medical Science Mashat GD, Hazique M, Khan KI, Ramesh P, Kanagalingam S, Ul Haq Z, et al.
Systematic Review Meta-Analysis Children's HealthHoney is effective in treating coughs in children above 12 months.
Acupuncture for Pain Management in Pediatric Patients with Sickle Cell Disease
2022 Jul 19 Children Plonski KS
Acupuncture is a promising and understudied therapy for the treatment of pain during an acute pain episode in pediatric patients with sickle cell disease (SCD).
Review Article Children's HealthClinical Trials
Clinical trials are research studies that involve people and are conducted to evaluate the safety and efficacy of new treatments or interventions, such as drugs, medical devices, or behavioural therapies.
Parent-administered pediatric tuina for the treatment of attention deficit hyperactivity disorder symptoms: Process evaluation of a pilot randomized controlled trial
2022 Nov Complementary Therapies in Medicine Chen SC, Cheng HL, Han LF, Wu GT, Zhang RY, Suen LKP, et al.
Implementation of parent-administered pediatric tuina intervention is feasible and acceptable. The intervention can be refined by improving the TCM pattern identification procedure and adjusting outcome settings in a fully powered study in the future.
Randomised Controlled Trial Children's HealthParent-administered pediatric Tuina for attention deficit/hyperactivity disorder symptoms in preschool children: A pilot randomized controlled trial embedded with a process evaluation
2022 Jul Phytomedicine Chen SC, Yu J, Wang HS, Wang DD, Sun Y, Cheng HL, et al.
Randomised Controlled Trial Children's Health Sleep Appetite ADHD Meridian MassageParent-administered pediatric tuina is effective at reducing core symptoms of ADHD in preschool children and improves child appetite and sleep quality.
Efficacy of Press Needle at PC6 Neiguan and ST36 Zusanli as Adjuvant Therapy in Reducing Symptoms of Chemotherapy-Induced Nausea and Vomiting in Pediatric Cancer Patients Undergoing Chemotherapy
2022 Apr 01 Medical Acupuncture Bintoro DA, Nareswari I, Andriastuti M
Press needle acupuncture is able to reduce the Rhodes index of nausea, vomiting, and retching (RINVR) score and can be applied to pediatric patients because of its minimal side effects, but further research is needed to determine the appropriate treatment time.
Randomised Controlled Trial Children's Health Acupuncture Chemotherapy-Induced Nausea and Vomiting Vomiting NauseaClinical observation of pediatric Tuina plus oral Chinese medication for pediatric anorexia due to spleen failing in transportation
2022 Apr Journal of Acupuncture and Tuina Science Xie T, Jiang H, Zhang C
Tuina manipulation of Yun Shui Ru Tu plus oral administration of Chinese medication is significantly effective in treating pediatric anorexia due to spleen failing in transportation, which can improve the appetite of children and improve the symptoms of anorexia, and the curative effect is better than that of oral administration of Chinese medication alone.
Randomised Controlled Trial Anorexia Meridian Massage Children's HealthOmega-3 fatty-acids modulate symptoms of depressive disorder, serum levels of omega-3 fatty acids and omega-6/omega-3 ratio in children. A randomized, double-blind and controlled trial
2020 May Psychiatry Research Trebatická J, Hradečná Z, Surovcová A, Katrenčíková B, Gushina I, Waczulíková I, et al.
The study concluded that an omega-3 fatty acid fish oil emulsion showed significant reductions in depressive symptoms and a decrease in omega-6/omega-3 ratio in the treatment group compared to the control group.
Clinical Study Randomised Controlled Trial Depression Children's Health Omega-6 Omega-3 RatioStudy Protocols
Published study protocols are detailed plans that outline the objectives, methodology, statistical analyses, and organisation of a research study that have been made publicly available for others to review and use as a reference.
Presentation Slides
Systematic Review
Honey potentially has superior results than cough medication or placebo in curtailing symptoms and enhancing sleep in children with acute cough.
Kuitunen I, Renko M
Systematic Review
Honey is effective in treating coughs in children above 12 months.
Mashat GD, Hazique M, Khan KI, Ramesh P, Kanagalingam S, Ul Haq Z, Victory Srinivasan N, Khan AI, Khan S
Randomised Controlled Trial
Parent-administered pediatric tuina is effective at reducing core symptoms of ADHD in preschool children and improves child appetite and sleep quality.
Chen SC, Yu J, Wang HS, Wang DD, Sun Y, Cheng HL, Suen LKP, Yeung WF
Clinical Study
The combination of Tuina (Chinese therapeutic massage) and Shen Ling Bai Zhu San is more effective in treating pediatric diarrhea due to spleen deficiency than Shen Ling Bai Zhu San alone.
Li J
Clinical Study
Consumption of pumpkin seeds enhances the nutritional status and improves the attention deficit of deaf female children exhibiting ADHD symptoms.
Ataya H
Review Article
Allergic rhinitis in children, according to traditional Chinese medicine, is interrelated with the functionality of lungs, spleen, and kidney and can be treated with combined Western and Chinese herbal medicines.
Liang J, Gu Q
Systematic Review
The use of Yu Ping Feng San for pediatric allergic rhinitis appears relatively safe compared to Western medical therapy yet its routine use remains unsupported.
Liao Y, Zhong J, Liu S, Dai M, Liu Y, Li X, Yang Y, Zhang D, Lai D, Lu T, Zhang Q, Zhao Y
Clinical Study
Magnesium-rich mineral water effectively treats and prevents constipation in children, leading to regular, painless bowel movements.
Kulikov AG, Zakharova IN, Tvorogova TM, Stepurina LL, Elezova LI
Review Article
Moderate‐certainty evidence showed that honey probably reduces cough duration to a greater extent than salbutamol or placebo. Honey group participants were first to get total relief of cough compared to salbutamol or placebo.
Oduwole O, Udoh EE, Oyo-Ita A, Meremikwu MM
Systematic Review
Traditional Chinese massage therapy can effectively treat asthma and significantly improve pulmonary function in children.
Ji Wu Xi-Wen Yang, and Ming Zhang
Review Article
Milk and honey mixture seems to be at least as effective as dextromethorphan and levodropropizine, the most prescribed over-the-counter antitussives in Italy, in non-specific acute cough in children.
Miceli Sopo S, Greco M, Monaco S, Varrasi G, Di Lorenzo G, Simeone G
Systematic Review
We cautiously suggest that acupuncture therapy could demonstrate better clinical efficacy than pharmacological treatment or placebo treatment in treating nocturnal enuresis.
Lv ZT, Song W, Wu J, et al.
Systematic Review
The efficacy of acupuncture for some pediatric conditions is promising, such as for cerebral palsy, nocturnal enuresis, tic disorders, amblyopia, and pain reduction.
Chunsong Yang, Zilong Hao, Ling-Li Zhang & Qin Guo
Review Article
Acupuncture is a safe complementary/alternative medicine modality for pediatric patients on the basis of the data we reviewed.
Jindal, Vanita; Ge, Adeline; Mansky, Patrick J.
Executive Summary
Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Children's Health" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.
Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Children's Health" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.
Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Children's Health" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.
A Systematic Review published in 2023 in the journal European Journal of Pediatrics found that Honey potentially has superior results than cough medication or placebo in curtailing symptoms and enhancing sleep in children with acute cough. Methodology: This targeted review leveraged multiple databases, such as PubMed, Scopus, CENTRAL, CINAHL, and Web of Science, to extract relevant trials relating to honey's usage in treating acute child cough. By applying a systematic approach, the emphasis was on randomized controlled trials featuring children. To ensure the results' credibility, payment was done for risk-of-bias as well as the quality of the evidence. The studies were not combined owing to the absence of essential information; instead, conclusions provided a range of noticed effects for principal results. Discussion of results: Following rigorous screening of almost four hundred papers, a select ten were incorporated. Significant variability in biases was noticed, with two studies possessing a high risk-of-bias and six inviting some concerns. The evidence, though of low to very low quality, indicated honey's potential superiority over placebo/no treatment and cough medication, both in reducing cough frequency and improving sleep quality.
A Systematic Review published in 2022 in the journal Cureus Journal of Medical Science found that Honey is effective in treating coughs in children above 12 months. The researchers undertook a systematic review of literature across five databases, using a Medical Subject Heading strategy, keywords, and defined inclusion and exclusion criteria to identify relevant studies. This review incorporated a range of study types, including systematic reviews, meta-analyses, randomized controlled trials, observational studies and cross-sectional studies. Those articles without a clear methodology section were excluded. The quality of the remaining literature was appraised using a specific checklist. Following the review, it was found that honey is effective in treating coughs in children older than 12 months. Cold and cough medications were also found to be safe, if given at therapeutic doses. However, a note of caution was highlighted for the use of these medications in children under two years, as fatalities have been recorded in some cases; although further studies are recommended to establish a clear safety profile.
A Randomised Controlled Trial published in 2022 in the journal Phytomedicine found that Parent-administered pediatric tuina is effective at reducing core symptoms of ADHD in preschool children and improves child appetite and sleep quality. This research involved a two-arm, parallel, open-label, pilot Randomized Controlled Trial, where 64 participants were assigned to two separate groups. Parents in the first group attended an online course teaching them pediatric tuina for ADHD, which they would then apply to their children at home. The second group of parents went through online training about a progressive muscle relaxation exercise and engaged in interactive physical activities with their children at home. Both groups carried out their respective interventions every other day for two month, each session lasting at least 20 minutes. The project measured the rate of recruitment, consent, participant adherence, retention and any adverse events. Upon investigation, both groups demonstrated improvements, with moderate effect size within each group. This was reflected in improvements in core hyperactivity and impulsivity symptoms. Parents also noticed positive changes in their children’s eating habits, sleep quality, and overall parent-child relationship. No serious issues were reported in relation to implementing the parent-administered pediatric tuina or from the interactive physical activity sessions.
A Clinical Study published in 2022 in the journal Journal of Acupuncture and Tuina Science found that The combination of Tuina (Chinese therapeutic massage) and Shen Ling Bai Zhu San is more effective in treating pediatric diarrhea due to spleen deficiency than Shen Ling Bai Zhu San alone. Methodology: The paper reports on a clinical trial involving a total of 105 children diagnosed with diarrhea due to spleen deficiency. These children were randomly allocated into two separate groups: a control group and an observation group. The control group, consisting of 52 children, were exclusively treated with Shen Ling Bai Zhu San orally. The observation group, on the other hand, consisted of 53 children who received an additional Tuina treatment along with Shen Ling Bai Zhu San. Results: After implementing the treatments, it was found that every child in the observation group showed improvement, compared to 90% improvement rate in the control group. This correlated to a decrease in scores of primary and secondary symptoms of traditional Chinese medicine in both groups post-treatment. Furthermore, the children in the observation group who received both treatments had even lower symptom scores than the control group who only received Shen Ling Bai Zhu San. The treatments were also well-tolerated with no significant adverse reactions reported.
A Clinical Study published in 2021 in the journal African Journal of Biological Sciences found that Consumption of pumpkin seeds enhances the nutritional status and improves the attention deficit of deaf female children exhibiting ADHD symptoms. This study investigated 40 deaf female children, aged between 10 and 12 years, who exhibited symptoms of attention-deficit hyperactivity disorder (ADHD). These children were selected from El Amal school for the deaf and divided into two groups; control and experimental. Various data were gathered on personal and socio-economic factors, food habits, diet history, and clinical signs, along with performing the Attention Deficit Disorder Connected with Hyperactivity for Deaf Children test. The experimental group underwent a dietary intervention, consuming 50g of magnesium and iron-rich pumpkin seeds daily over three months. The results indicated an improvement in both iron and magnesium levels within the experimental group following the dietary intervention. Notably, compared to the control group, the levels of magnesium and iron were significantly higher in the experimental group after introducing pumpkin seeds into their diet. Furthermore, on evaluating the ADHD symptoms via the Attention Deficit Disorder Connected with Hyperactivity for Deaf Children test, the experimental group showed a more substantial improvement after dietary intervention than the control group. Over time, the findings demonstrated the potential beneficial effects of consuming pumpkin seeds on the nutritional status and ADHD symptoms in the studied population.
A Review Article published in 2021 in the journal Translational Pediatrics found that Allergic rhinitis in children, according to traditional Chinese medicine, is interrelated with the functionality of lungs, spleen, and kidney and can be treated with combined Western and Chinese herbal medicines. The methodology of this study was based on a review of both traditional Chinese and Western medical theories and practices. Chinese theory postulates that BiQiu, or allergic rhinitis in children, is primarily related to a congenital deficiency in vital qi, dysfunction of the lungs inhibiting nose orifices, and a deficiency of spleen and kidney leading to lung qi deficiency. The review looked into herbal monomers and compounds of Chinese herbal medicines as potential treatments for allergic rhinitis, while also considering the impact of external factors like the cold and inadequate diet. The review highlighted some of the effects and shortcomings of Chinese herbal medicines used alongside Western medicines for treating allergic rhinitis. Particularly, it focussed on how the unique perceptions of life science of the human body from both Eastern and Western cultures can be brought together for a comprehensive method of treatment. The study also outlined future trends of research to enhance this combined treatment approach.
A Systematic Review published in 2021 in the journal Medicine found that The use of Yu Ping Feng San for pediatric allergic rhinitis appears relatively safe compared to Western medical therapy yet its routine use remains unsupported. The study undertakes a systematic search across multiple databases, including PubMed, the Excerpta Medical Database, Cochrane library and more, for randomized controlled trials (RCTs) concerning the use of YPFS for pediatric allergic rhinitis. Extracted results were subjected to stringent bias-risk analysis based on the Cochrane Handbook. A meta-analysis was then implemented using RevMan 5.3 software, and the Grading of Recommendations Assessment, Development and Evaluation methodology was applied to check the quality of evidence for every outcome. The study pooled 10 RCTs covering 1,069 participants aged between 3-15 years for initial inclusion. After certain exclusions, it was determined from the remaining eight RCTs that the overall efficacy did not show any notable advantage for the test group. In addition, inspections into variation of serum immunoglobulin levels showed no statistical significance. However, the safety of YPFS displayed better results, demonstrating a relatively safer approach with lower recurrence rates compared to Western medical therapy.
A Clinical Study published in 2020 in the journal Russian Journal of Physiotherapy, Balneology and Rehabilitation found that Magnesium-rich mineral water effectively treats and prevents constipation in children, leading to regular, painless bowel movements. This randomized, prospective, open, comparative study involved 95 children and adolescents aged 10-16 years with functional constipation. They received sanatorium therapy for 18 days, including a sparing-exercise regimen, therapeutic nutrition, health-improving massage, and physiotherapy exercises. Participants were divided into two groups: Group 1 (55 patients) received basic treatment plus magnesium-containing mineral water, while Group 2 (40 patients) received only basic treatment. The study assessed the frequency and nature of defecation, vegetative status, and functional body reserves. By day 5, 49% of Group 1 patients achieved daily defecation, increasing to 89.1% by the end of treatment. In contrast, only 55% of Group 2 showed positive changes by the end. The mineral water group also had softer, pain-free bowel movements, with most achieving a morning defecation reflex after consuming the water. The control group saw less significant changes in defecation nature, with only 18% reaching softer bowel movements by the end of treatment. The results indicate the effectiveness and safety of magnesium-containing mineral water in treating and preventing functional constipation in children.
A Review Article published in 2018 in the journal Cochrane Database of Systematic Reviews found that Moderate‐certainty evidence showed that honey probably reduces cough duration to a greater extent than salbutamol or placebo. Honey group participants were first to get total relief of cough compared to salbutamol or placebo. Honey probably relieves cough symptoms to a greater extent than no treatment, diphenhydramine, and placebo, but may make little or no difference compared to dextromethorphan. Honey probably reduces cough duration better than placebo and salbutamol. There was no strong evidence for or against using honey. Most of the children received treatment for one night, which is a limitation to the results of this review. There was no difference in occurrence of adverse events between the honey and control arms.
A Systematic Review published in 2017 in the journal Evidence-Based Complementary and Alternative Medicine found that Traditional Chinese massage therapy can effectively treat asthma and significantly improve pulmonary function in children. In this meta-analysis, we evaluated the effects of massage on treatment of children asthma. The findings produced by the fixed-effects model indicate that massage therapy can significantly increase the efficacy of the treatment on children asthma and improve pulmonary function index FEV1 and PEF. However, we could not conclude the favorable mechanism of massage in the overall meta-analysis due to the small number of articles. All studies have shown that massage therapy has a significantly positive effect on children with asthma, improves the pulmonary function parameters of large airway, reduces the plasma concentrations of PAF and prostaglandin, and increases the levels of PAF-AH and DP1; therefore, it greatly improves pulmonary function. However, the limited research designs of included studies lead to high risk of bias. More randomized controlled trials with better methodological quality are needed to further confirm the effectiveness of massage.
A Review Article published in 2015 in the journal Allergologia et Immunopathologia found that Milk and honey mixture seems to be at least as effective as dextromethorphan and levodropropizine, the most prescribed over-the-counter antitussives in Italy, in non-specific acute cough in children. Honey is recommended for non-specific acute paediatric cough by the Australian guidelines. Current available randomised clinical trials evaluated the effects of a single evening dose of honey, but multiple doses outcomes have never been studied. 134 children suffering from non-specific acute cough were randomised to receive for three subsequent evenings a mixture of milk (90 ml) and wildflower honey (10 ml) or a dose of DM or LDP adjusted for the specific age. The effectiveness was evaluated by a cough questionnaire answered by parents. Primary end-point efficacy was therapeutic success. The latter was defined as a decrease in cough questionnaire score greater than 50% after treatment compared with baseline values. Three children were excluded from the study, as their parents did not complete the questionnaire. Therapeutic success was achieved by 80% in the honey and milk group and 87% in OTC medication group (p = 0.25).
A Systematic Review published in 2015 in the journal Evidence-Based Complementary and Alternative Medicine found that We cautiously suggest that acupuncture therapy could demonstrate better clinical efficacy than pharmacological treatment or placebo treatment in treating nocturnal enuresis. In summary, the results of this study suggest that acupuncture therapy demonstrate better clinical efficacy than pharmacological treatment or placebo treatment in treating NE. Due to the low methodological qualities of included trials, the findings of current study should be interpreted with caution. Therefore, to further assess the potential beneficial effect of acupuncture therapy for NE, additional RCTs with rigorous experimental design, large-scale high quality methodological control, long follow-ups, and strict reporting specification are required.
A Systematic Review published in 2015 in the journal Pediatric Research found that The efficacy of acupuncture for some pediatric conditions is promising, such as for cerebral palsy, nocturnal enuresis, tic disorders, amblyopia, and pain reduction. This overview identified 24 systematic reviews, providing us with a comprehensive picture of acupuncture for pediatric conditions. Although most of the included studies could not draw firm conclusions because of the small size of the included trials or their low methodological quality, the efficacy of acupuncture for some pediatric conditions is promising, such as for cerebral palsy, nocturnal enuresis, tic disorders, amblyopia, and pain reduction. However, the efficacy of acupuncture for hypoxic–ischemic encephalopathy, attention deficit hyperactivity disorder, mumps, and myopia is unclear and the efficacy for ASD, asthma, and nausea/vomiting is controversial. Current evidence does not support the use of acupuncture for pediatric epilepsy. In this overview, we found that acupuncture was well tolerated and no fatal side effects were reported.
A Review Article published in 2008 in the journal Journal of Pediatric Hematology/Oncology found that Acupuncture is a safe complementary/alternative medicine modality for pediatric patients on the basis of the data we reviewed. We reviewed 31 different published journal articles, including 23 randomized controlled clinical trials and 8 meta-analysis/systematic reviews. We found evidence of some efficacy and low risk associated with acupuncture in pediatrics.
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The scientific evidence for efficacy of omega-3 supplementation in reducing symptoms of depression and anxiety in young people is inconclusive, however, it was found that most "grey literature" sources recommended the use of omega-3 supplements in young people. —Jinnan C 20 Oct 2023