Huang Qi
Also known as: Astragalus Membranaceus, Radix Astragali
Recent Insights
Zhangyanming Tablets show potential as a protective agent for retinal function in early-stage, genetically-caused blindness in mice, possibly due to their antioxidant and anti-/pro-apoptotic properties.
Dang Shen Ge Gen Goji Berry
HuoXiang ZhengQi (HQXXD) may be a safe and effective treatment for Chronic Cough Variant Asthma (CVA), improving clinical efficacy and airway responsiveness while reducing recurrence rates.
Asthma Cough Huang Qi
Various traditional Chinese medicine treatment strategies could potentially provide an effective alternative in slowing the progression of Chronic Kidney Disease.
Chronic Kidney Disease Dan Shen Dang Gui
Chinese herbal medicines could alleviate chronic kidney disease symptoms by combating fibrosis, inflammation, oxidative stress, and encouraging repair and regeneration.
Dan Shen Ge Gen Huang Kui
Related Topics
Research Articles
Published research studies are articles that present the findings of original research that has undergone a peer-review process and has been made publicly available in scholarly journals, books or other media.
Protective effect of ZYMT, a traditional Chinese patent medicine in a mouse model of retinitis pigmentosa
2023 Jun Biomedicine & Pharmacotherapy Huang Z, Huang Q, Xu K, Liang L, Li Y, Zhou W, et al.
Experimental Study Animal Study Dang Shen Shu Di Huang Huang Qi Ge Gen Goji Berry Zhang Yan Ming Tablets Retinitis PigmentosaZhangyanming Tablets show potential as a protective agent for retinal function in early-stage, genetically-caused blindness in mice, possibly due to their antioxidant and anti-/pro-apoptotic properties.
Astragalus propinquus schischkin and Salvia miltiorrhiza bunge promote angiogenesis to treat myocardial ischemia via Ang-1/Tie-2/FAK pathway
2023 Jan 09 Frontiers in Pharmacology Zhang MX, Huang XY, Song Y, Xu WL, Li YL, Li C
Astragalus propinquus Schischkin (Huang Qi) and Salvia miltiorrhiza Bunge (Dan Shen) (AS) can treat myocardial ischemia (MI) by protecting cardiac function, attenuating cardiac pathological changes, and hindering the progression of heart failure, which is related to angiogenesis after pericyte recruitment.
Network Pharmacology Dan Shen
The Latest Research Advances of Danggui Buxue Tang as an Effective Prescription for Various Diseases: A Comprehensive Review
2022 Oct Current Medical Science Ma C, Jiang Y, Wang Y, Xu R
Based on TCM theory, DBT is mainly used to treat fatigue, thirst, weakness, women’s menstrual periods and postpartum fever, anemia, and other blood deficiency syndromes. Modern pharmacological experiments have demonstrated that DBT possesses a wide range of biological activities, thus showing remarkable medicinal value. The use of DBT can provide more treatment options for diseases with clinical manifestations such as hemocytopenia, DN, nerve damage, cardiovascular and cerebrovascular diseases, fibrosis, and cancer.
Review Article Huang Qi Dang Gui Bu Xue TangThe Effectiveness and Safety of Huangqi Xixin Decoction for Cough Variant Asthma: A Systematic Review and Meta-Analysis
2022 Sep 20 Evidence-Based Complementary and Alternative Medicine Wang C, Xia Q, Hu B, Jiang W, Zhang H
Systematic Review Meta-Analysis Huangqi Xixin decoction Cough Huang Qi Asthma Xi XinHuoXiang ZhengQi (HQXXD) may be a safe and effective treatment for Chronic Cough Variant Asthma (CVA), improving clinical efficacy and airway responsiveness while reducing recurrence rates.
Traditional Chinese Medicine in the Treatment of Chronic Kidney Diseases: Theories, Applications, and Mechanisms
2022 Jul 18 Frontiers in Pharmacology Yunlai Wang, Ye Feng, Manman Li, Mo Yang, Gaoxiang Shi, Zihua Xuan, et al.
Review Article Chronic Kidney Disease Huang Qi San Qi Dang Gui Qu Feng Tong Luo Recipe Dan Shen Zhen Wu Decoction Fu LingVarious traditional Chinese medicine treatment strategies could potentially provide an effective alternative in slowing the progression of Chronic Kidney Disease.
Research Insights
Insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.
Zhangyanming Tablets show potential as a protective agent for retinal function in early-stage, genetically-caused blindness in mice, possibly due to their antioxidant and anti-/pro-apoptotic properties.
2023 Biomedicine & Pharmacotherapy Protective effect of ZYMT, a traditional Chinese patent medicine in a mouse model of retinitis pigmentosa Huang Z, Huang Q, Xu K, Liang L, Li Y, Zhou W, et al.
Experimental Study Dang Shen Ge Gen Goji Berry
Eighty mice with Retinitis Pigmentosa (RP) were divided into two groups, with one group receiving Zhangyanming Tablets (ZYMT) and a control group getting distilled water. After a period of 7 and 14 days, the researchers conducted tests through electroretinogram, fundus photography, and histological examination to assess the retinal function and structure of the subjects. They furthered the study using TUNEL, immunofluorescence and qPCR to evaluate cell apoptosis and the expressions of particular genes.
The ZYMT-treated mice displayed a notable enhancement in retinal reactions and overall preservation of retinal structure when compared to the control group. Particularly noticeable were increases in retinal thickness and cell count, alongside a significantly lowered rate of cell death. A comprehensive follow-up shows the altered expressions of several genes in the retina following the application of ZYMT. These results, combined, suggest a key role of ZYMT in mitigating the effects of RP especially in early stages.
HuoXiang ZhengQi (HQXXD) may be a safe and effective treatment for Chronic Cough Variant Asthma (CVA), improving clinical efficacy and airway responsiveness while reducing recurrence rates.
2022 Evidence-Based Complementary and Alternative Medicine The Effectiveness and Safety of Huangqi Xixin Decoction for Cough Variant Asthma: A Systematic Review and Meta-Analysis Wang C, Xia Q, Hu B, Jiang W, Zhang H
Systematic Review Asthma Cough Huangqi Xixin decoction
HuoXiang ZhengQi (HQXXD) for Chronic Cough Variant Asthma (CVA) was systematically evaluated. The HQXXD group showed significantly higher total effective rates of clinical efficacy and airway responsiveness compared to the control group, while the recurrence rate was lower. Adverse reactions were not reported in HQXXD treatment, indicating its safety for CVA patients.
Various traditional Chinese medicine treatment strategies could potentially provide an effective alternative in slowing the progression of Chronic Kidney Disease.
2022 Frontiers in Pharmacology Traditional Chinese Medicine in the Treatment of Chronic Kidney Diseases: Theories, Applications, and Mechanisms Yunlai Wang, Ye Feng, Manman Li, Mo Yang, Gaoxiang Shi, Zihua Xuan, et al.
Review Article Chronic Kidney Disease Dan Shen Dang Gui
The study explores the use of Traditional Chinese Medicine (TCM) and various Chinese materia medica (CMM) to manage Chronic Kidney Disease (CKD). The review delves deeper into the principles and treatment approaches of TCM in battling CKD, dictating that the disease's nature is deficient in the root and excessive in the branches, where deficiency and excess persist simultaneously throughout the condition. The main strategies employed by TCM in the treatment of CKD include invigorating Qi, tonifying kidneys, promoting blood circulation, removing stasis, eliminating heat and dampness, reducing turbidity, and controlling edema.
The discussion highlights the effectiveness of several CMMs in treating CKD, which are undergirded by clinical evidence or experimental studies. Notably, it points out a correlation between the macroscopic view of TCM and the microscopic view of modern medicine. These TCM and CMM strategies are hailed for their multi-targeted and multi-functional characteristics, potentially providing an effective alternative treatment approach for CKD.
Chinese herbal medicines could alleviate chronic kidney disease symptoms by combating fibrosis, inflammation, oxidative stress, and encouraging repair and regeneration.
2021 Frontiers in Pharmacology New Insights Into the Effects of Individual Chinese Herbal Medicines on Chronic Kidney Disease Shao M, Ye C, Bayliss G, Zhuang S
Review Article Dan Shen Ge Gen Huang Kui
The study's methodology consisted of both clinical and experimental approaches. It started with an examination of an array of traditional Chinese herbs. The criteria for considered herbs were their clinical efficacy, frequency of use in treating chronic renal disease, and a well-studied mechanism of action. Five herbs, namely, Tanshinone II A, Salvianolic acid A & B, Triptolide, Tripterygium glycosides and a monomer from Kudzu root, made the cut after having met the set criteria.
The results showed that these Chinese herbs were found to possess pharmaceutical properties that were effective against fibrosis, inflammation, and oxidative stress. Furthermore, these also showed the potential to promote renal repair and regeneration, which are fundamental for treating chronic kidney disease. These findings suggest a broader scope of therapeutic treatments that could benefit the patients in a more natural and potentially less invasive way.
Review Articles
Review articles summarise and critically evaluate the current state of research on a specific topic or field by synthesising multiple primary research studies.
The Latest Research Advances of Danggui Buxue Tang as an Effective Prescription for Various Diseases: A Comprehensive Review
2022 Oct Current Medical Science Ma C, Jiang Y, Wang Y, Xu R
Based on TCM theory, DBT is mainly used to treat fatigue, thirst, weakness, women’s menstrual periods and postpartum fever, anemia, and other blood deficiency syndromes. Modern pharmacological experiments have demonstrated that DBT possesses a wide range of biological activities, thus showing remarkable medicinal value. The use of DBT can provide more treatment options for diseases with clinical manifestations such as hemocytopenia, DN, nerve damage, cardiovascular and cerebrovascular diseases, fibrosis, and cancer.
Review Article Huang Qi Dang Gui Bu Xue TangThe Effectiveness and Safety of Huangqi Xixin Decoction for Cough Variant Asthma: A Systematic Review and Meta-Analysis
2022 Sep 20 Evidence-Based Complementary and Alternative Medicine Wang C, Xia Q, Hu B, Jiang W, Zhang H
Systematic Review Meta-Analysis Huangqi Xixin decoction Cough Huang Qi Asthma Xi XinHuoXiang ZhengQi (HQXXD) may be a safe and effective treatment for Chronic Cough Variant Asthma (CVA), improving clinical efficacy and airway responsiveness while reducing recurrence rates.
Traditional Chinese Medicine in the Treatment of Chronic Kidney Diseases: Theories, Applications, and Mechanisms
2022 Jul 18 Frontiers in Pharmacology Yunlai Wang, Ye Feng, Manman Li, Mo Yang, Gaoxiang Shi, Zihua Xuan, et al.
Review Article Chronic Kidney Disease Huang Qi San Qi Dang Gui Qu Feng Tong Luo Recipe Dan Shen Zhen Wu Decoction Fu LingVarious traditional Chinese medicine treatment strategies could potentially provide an effective alternative in slowing the progression of Chronic Kidney Disease.
New Insights Into the Effects of Individual Chinese Herbal Medicines on Chronic Kidney Disease
2021 Nov 04 Frontiers in Pharmacology Shao M, Ye C, Bayliss G, Zhuang S
Review Article Ge Gen Huang Qi Lei Gong Teng Dan Shen Huang KuiChinese herbal medicines could alleviate chronic kidney disease symptoms by combating fibrosis, inflammation, oxidative stress, and encouraging repair and regeneration.
Radix Astragali and Radix Angelicae Sinensis in the Treatment of Idiopathic Pulmonary Fibrosis: A Systematic Review and Meta-analysis
2020 Apr 30 Frontiers in Pharmacology Zhang Y, Gu L, Xia Q, Tian L, Qi J, Cao M
RA and RAS are effective and safe in the treatment of IPF, which is beneficial to pulmonary function and exercise tolerance of these patients.
Systematic Review Meta-Analysis Huang Qi Dang GuiPresentation Slides
Zhangyanming Tablets show potential as a protective agent for retinal function in early-stage, genetically-caused blindness in mice, possibly due to their antioxidant and anti-/pro-apoptotic properties.
HuoXiang ZhengQi (HQXXD) may be a safe and effective treatment for Chronic Cough Variant Asthma (CVA), improving clinical efficacy and airway responsiveness while reducing recurrence rates.
Various traditional Chinese medicine treatment strategies could potentially provide an effective alternative in slowing the progression of Chronic Kidney Disease.
Chinese herbal medicines could alleviate chronic kidney disease symptoms by combating fibrosis, inflammation, oxidative stress, and encouraging repair and regeneration.
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Zhangyanming Tablets (ZYMT) has been in clinical use for almost 4 decades. The main components of this medicine include Fructus Lycii (wolfberry), Radix Codonopsis, Radix Astragali, Radix Puerariae Lobatae, Radix Rehmanniae Praeparata and so on. —Jinnan C 25 Apr 2024