Anti-Ageing

Presentation Slides

Chinese Medicine Research Hub

Cohort Study

Regular nut consumption, particularly peanuts and walnuts, is associated with a lower incidence of frailty in aging female populations.

2023 The Journal of Nutrition Long-Term Consumption of Nuts (Including Peanuts, Peanut Butter, Walnuts, and Other Nuts) in Relation to Risk of Frailty in Older Women: Evidence from a Cohort Study
Wang R, Hannan MT, Wang M, Schwartz AW, Lopez-Garcia E, Grodstein F

Chinese Medicine Research Hub

Systematic Review

Ginger, native to Southeast Asia, possesses antioxidant and antiviral properties, contributing to healthy ageing and potential prevention of age-related disorders.

2022 Oxidative Medicine and Cellular Longevity Ginger for Healthy Ageing: A Systematic Review on Current Evidence of Its Antioxidant, Anti-Inflammatory, and Anticancer Properties
Ozkur M, Benlier N, Takan I, Vasileiou C, Georgakilas AG, Pavlopoulou A, Cetin Z, Saygili EI

Chinese Medicine Research Hub

Systematic Review

Chinese herbal medicines or their components can potentially delay aging by regulating aging-related genes via different signaling pathways.

2021 Evidence-Based Complementary and Alternative Medicine A Systematic Review of Antiaging Effects of 23 Traditional Chinese Medicines
Wang L, Zuo X, Ouyang Z, Qiao P, Wang F

Chinese Medicine Research Hub

Systematic Review

Cocoa flavanols exhibit health and aging benefits and may act as powerful agents in preventing chronic diseases such as cardiovascular and metabolic disorders, and cancer.

2021 Food and Chemical Toxicology Impact of cocoa flavanols on human health
Martin M, Ramos S

Chinese Medicine Research Hub

Systematic Review

The study shows the promising potential of Suan Zao Ren as a multi-effect traditional Chinese medicine derived from the seeds of Ziziphus Jujuba.

2020 Evidence-Based Complementary and Alternative Medicine Botanical and Traditional Uses and Phytochemical, Pharmacological, Pharmacokinetic, and Toxicological Characteristics of Ziziphi Spinosae Semen: A Review
Su-Rong He, Chong-Bo Zhao, Jing-Xia Zhang, Jing Wang, Bo Wu, Chun-Jie Wu,

Chinese Medicine Research Hub

Systematic Review

The health benefits of goji berries include enhancing hemopoiesis, antiradiation, antiaging, anticancer, improvement of immunity, and antioxidation.

2019 Oxidative Medicine and Cellular Longevity Goji Berries as a Potential Natural Antioxidant Medicine: An Insight into Their Molecular Mechanisms of Action
Zheng Feei Ma, Hongxia Zhang, Sue Siang Teh, Chee Woon Wang, Yutong Zhang, Frank Hayford, Liuyi Wang, Tong Ma, Zihan Dong, Yan Zhang, Yifan Zhu,

Chinese Medicine Research Hub

Systematic Review

Goji berries, rich in antioxidants, confer health benefits including protection against aging, cancer, and radiation, as well as enhancing immunity and blood production.

2019 Oxidative Medicine and Cellular Longevity Goji Berries as a Potential Natural Antioxidant Medicine: An Insight into Their Molecular Mechanisms of Action
Zheng Feei Ma, Hongxia Zhang, Sue Siang Teh, Chee Woon Wang, Yutong Zhang, Frank Hayford, Liuyi Wang, Tong Ma, Zihan Dong, Yan Zhang, Yifan Zhu,

Chinese Medicine Research Hub

Randomised Controlled Trial

Daily consumption of tart cherry juice may enhance cognitive abilities in older adults, likely due to reduction of hypertension, inflammation, and oxidative stress.

2019 Food & Function Effect of Montmorency tart cherry juice on cognitive performance in older adults: a randomized controlled trial
Chai SC, Jerusik J, Davis K, Wright RS, Zhang Z

Executive Summary

Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Anti-Ageing" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.

Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Anti-Ageing" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.

Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Anti-Ageing" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.

A Cohort Study published in 2023 in the journal The Journal of Nutrition found that Regular nut consumption, particularly peanuts and walnuts, is associated with a lower incidence of frailty in aging female populations. The methodology of the study includes a population-based observational study of nonfrail women aged 60 and above from 11 states across the US, from the Nurses' Health Study. The outcome focused on incidence of frailty, defined through the FRAIL components such as fatigue, lower strength, reduced aerobic capacity, multiple chronic conditions, and significant weight loss. These were assessed every four years from 1992 to 2016. Food Frequency Questionnaires were used to examine the intake of peanuts, peanut butter, walnuts, and other nuts every four years from 1990 to 2014. Total nut consumption was calculated and categorized into varying serving sizes, and the relation of intake of each type of nut with frailty was examined separately using Cox proportional hazard models, adjusted for various factors such as age, smoking, BMI, diet quality, and medication use. In discussing the results, out of 71,704 participants, 14,195 frailty cases arose over a million person-years. Notably, regular consumption of nuts, particularly peanuts and walnuts, showed a significant inverse relation with frailty. That is, a higher intake of these types of nuts were associated with lower cases of frailty. However, the same didn't apply to peanut butter. This affirms the potential benefits of regular nut consumption in aging female population's health and well-being.

A Systematic Review published in 2022 in the journal Oxidative Medicine and Cellular Longevity found that Ginger, native to Southeast Asia, possesses antioxidant and antiviral properties, contributing to healthy ageing and potential prevention of age-related disorders. The study explored the natural benefits of ginger, a plant native to Southeast Asia renowned for its culinary and medicinal uses. The approach focused on examining the plant's antioxidant, anti-inflammatory, anticancer, antimicrobial, and particularly antiviral properties from its rich collection of antiviral compounds. The process involved digging into accumulated evidence that suggests ginger's role in promoting healthy ageing, reducing morbidity, and prolonging a healthy lifespan, thus providing a natural solution for an age-old problem. In terms of results, the examination of evidence proved affirming. Ginger displayed significant potential in boosting healthy ageing, reducing the risk of age-related disorders, and extending a wholesome life expectancy due to its inherent properties. The plant's antioxidant characteristics played a key role in these outcomes, along with its anti-inflammatory and antiviral attributes. In essence, the research unfolded a rather underexplored potential of a common natural product in tackling age-induced health conditions.

A Systematic Review published in 2021 in the journal Evidence-Based Complementary and Alternative Medicine found that Chinese herbal medicines or their components can potentially delay aging by regulating aging-related genes via different signaling pathways. The methodology for this paper involved conducting a systematic literature review of studies published in the past five years. The databases used for this purpose included PubMed, EMBASE, Scopus, and Web of Science. Out of a total of 2485 papers initially located, 212 were selectively screened based on the elimination of duplicate entries and their title relevance. The final selection comprised 23 studies suitable for the review. Among these studies, 13 utilized mice as the animal model, while 10 employed alternative animal models or cell lines. The results showed that Chinese herbal medicine and their active components play a significant role in combating aging. This is achieved through the regulation of genes associated with aging via various signaling pathways. This leads to the conclusion that there is significant potential for the development of Chinese herbal medicines as antiaging drugs, or for their utilization within the medical cosmetology industry.

A Systematic Review published in 2021 in the journal Food and Chemical Toxicology found that Cocoa flavanols exhibit health and aging benefits and may act as powerful agents in preventing chronic diseases such as cardiovascular and metabolic disorders, and cancer. This research primarily relies on a comprehensive review of numerous human studies conducted over the past two decades. These studies provided significant data related to the health effects of cocoa intake and its impact on various chronic diseases. The studies encompassed different demographics and health conditions. Though most studies indicate beneficial effects of cocoa on health and prevention of chronic diseases, the results exhibit some inconsistency. Different studies suggest various mechanisms of action for cocoa, but these potential pathways are still not completely understood. Also, crucial issues like recommending cocoa consumption to healthy subjects or patients, determining the appropriate dosage, or the period of intake remain unresolved. Despite these unclarities, the potential of cocoa use to decrease the risk for certain chronic diseases and improve general health and quality of life is emphasized.

A Systematic Review published in 2020 in the journal Evidence-Based Complementary and Alternative Medicine found that The study shows the promising potential of Suan Zao Ren as a multi-effect traditional Chinese medicine derived from the seeds of Ziziphus Jujuba. The methodology of the research was primarily a comprehensive literature review of Ziziphi Spinosae Semen (aka Suan Zao Ren). The team explored the botanical characteristics, traditional uses, pharmacology, and discovered compounds in the seeds of Ziziphus Jujuba. In regards to the results of the review, more than 150 compounds were identified in Ziziphi Spinosae Semen. These compounds, which mainly include terpenoids, flavonoids and others, show various biological activities. It was found that the seeds are particularly prominent in having sedative and hypnotic effects. Other properties discovered include antitumor potential, improvement to learning and memory, anti-inflammatory, antioxidative, anti-aging, alongside lower blood pressure and lipid levels. Traditional usage of the seeds for the treatment of insomnia, forgetfulness, headaches and dizziness were confirmed by the review.

A Systematic Review published in 2019 in the journal Oxidative Medicine and Cellular Longevity found that The health benefits of goji berries include enhancing hemopoiesis, antiradiation, antiaging, anticancer, improvement of immunity, and antioxidation. Goji berries are a high antioxidant potential fruits which alleviate oxidative stress to confer many health protective benefits such as preventing free radicals from damaging DNA, lipids, and proteins. There is a better protection through synergistic and additive effects in fruits and herbal products from a complex mixture of phytochemicals than from a single phytochemical. The health benefits of goji berries include enhancing hemopoiesis, antiradiation, antiaging, anticancer, improvement of immunity, and antioxidation.

A Systematic Review published in 2019 in the journal Oxidative Medicine and Cellular Longevity found that Goji berries, rich in antioxidants, confer health benefits including protection against aging, cancer, and radiation, as well as enhancing immunity and blood production. The methodology of the study focused on a thorough review of the bioactive compounds and pharmacological properties of goji berries, particularly targeting their molecular mechanisms of action. This involved looking at the different ways these fruits are consumed, such as in soups, herbal teas, tinctures, wine, and juice, and how these methods influence the antioxidants present in the fruits. Goji berries were found to offer a range of health benefits due to their ability to alleviate oxidative stress. These benefits include enhancing hemopoiesis (blood formation), offering antiradiation and antiaging properties, inhibiting cancer, improving immunity, and providing antioxidation. Furthermore, the study emphasized that the complex mixture of phytochemicals found in fruits and herbal products like goji berries provide a cumulative protective effect, which proves more beneficial compared to extracting and using one single phytochemical.

A Randomised Controlled Trial published in 2019 in the journal Food & Function found that Daily consumption of tart cherry juice may enhance cognitive abilities in older adults, likely due to reduction of hypertension, inflammation, and oxidative stress. In this randomized controlled trial, 37 adults aged between 65 and 80 years with normal cognitive function were assigned to consume two cups of Montmorency tart cherry juice daily for a duration of 12 weeks. Participants' subjective memory and objective cognitive performance were evaluated at the starting point and after the 12-week juice supplementation using a validated memory questionnaire and a standard assortment of tests designed for cognitive assessment. Factors such as daily caloric intake and physical activity levels were also monitored during the study. After the 12-week intervention, participants who consumed tart cherry juice showed an improvement in their contentment with memory scores, demonstrated decreased scores of movement time, and performed better on a task of paired associates learning when compared to the control group. Notably, the results revealed that the tart cherry juice group demonstrated improvements on measures of visual sustained attention and spatial working memory relative to their own baseline values. These findings suggest that the potential benefits of tart cherry juice to cognitive abilities might be attributed to the juice's antioxidant and anti-inflammatory properties, and its capacity to reduce blood pressure.

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