HIV
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Traditional Chinese medicine, including acupuncture, can provide superior pain relief and faster recovery for HIV-related Herpes Zoster compared to regular drugs.
HIV Shingles
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Cancer prevention and therapy with kiwifruit in Chinese folklore medicine: a study of kiwifruit extracts
2023 Aug Journal of Ethnopharmacology Motohashi N, Shirataki Y, Kawase M, Tani S, Sakagami H, Satoh K, et al.
Network Pharmacology Antioxidant Kiwifruit AntibacterialGold kiwifruit extracts contained different bioactive materials which showed selective cytotoxic activity against human oral tumor cells and displayed anti-HIV, antioxidant, and antibacterial activities.
Successful management of chronic urticaria and food allergies in a pediatric population using integrative traditional Chinese medicine therapy: a case series
2022 Nov 25 Clinical and Molecular Allergy Fan X, McKnight T, Neshiwat J, Park S, Chung D, Li XM
Three pediatric patients with a known history of multiple food sensitivities and physician-diagnosed food allergies that presented with frequent, persistent, and difficult to treat hives (FPDTH) underwent a TCM regimen and experienced dramatic improvement in symptoms and reduction in their IgE levels.
Case Report Food Allergy Children's HealthEffects and safety of Chinese herbal medicine on inflammatory biomarkers in cardiovascular diseases: A systematic review and meta-analysis of randomized controlled trials
2022 Aug 16 Frontiers in Cardiovascular Medicine Li M, Zhou IW, Trevillyan J, Hearps AC, Zhang AL, Jaworowski A
Systematic Review Meta-Analysis Cardiovascular DiseaseThe Anti-Viral Activity of Prunella vulgaris: A Narrative Review
2022 Jul 01 Integrative Medicine Reports Mak WCK, Walsh S
investigators found that polysaccharides, polyphenolics, triterpenoic acids, and essential oils in P. vulgaris were potent to be anti-viral. The most frequently investigated viral types were HIV, HSV, and influenza virus, to which P. vulgaris extracts were found to be effective. P. vulgaris extracts exhibited good anti-viral activities. However, there is difficulty in producing a collective, summarized, and quantitative analysis from the reviewed articles to the anti-viral effects of P. vulgaris due to the complexity and diverse focus of investigations reported.
Review Article AntiviralTraditional Chinese Medicine for HIV-Associated Acute Herpes Zoster: A Systematic Review and Meta-Analysis of Randomized Trials
2022 Feb 18 Evidence-Based Complementary and Alternative Medicine Jiang Y, Zheng RX, Yu ZY, Zhang XW, Li J, Lan HD, et al.
Systematic Review Meta-Analysis HIV ShinglesTraditional Chinese medicine, including acupuncture, can provide superior pain relief and faster recovery for HIV-related Herpes Zoster compared to regular drugs.
Research Insights
Insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.
Gold kiwifruit extracts contained different bioactive materials which showed selective cytotoxic activity against human oral tumor cells and displayed anti-HIV, antioxidant, and antibacterial activities.
2023 Journal of Ethnopharmacology Cancer prevention and therapy with kiwifruit in Chinese folklore medicine: a study of kiwifruit extracts Motohashi N, Shirataki Y, Kawase M, Tani S, Sakagami H, Satoh K, et al.
Network Pharmacology Antibacterial Antioxidant Kiwifruit
The methodology involved stepwise extraction of gold kiwifruit with hexane, acetone, methanol, and 70% methanol; the extracts were then fractionated using silica gel and ODS column chromatographies to examine their biological activities. Different fractions like H1, H2 (from the hexane extract), A1, A2 (from the acetone extract), and M2 (from the methanol extract) were tested, as well as more hydrophilic fractions from the 70% methanol extract.
In the discussion of the results, fractions H1, H2, A1, A2 and M2 displayed notable cytotoxic activity against human oral tumor cell lines, with these showing more sensitivity compared to human gingival fibroblasts. The hydrophilic fractions from the 70% methanol extract demonstrated higher anti-HIV activity, radical generation, and oxygen scavenging activity. However, the antibacterial activity of these fractions was generally lower than that of the more lipophilic (hexane, acetone, methanol) extracts, indicating no distinct antimicrobial action. Interestingly, all fractions were inactive against Helicobacter pylori.
Traditional Chinese medicine, including acupuncture, can provide superior pain relief and faster recovery for HIV-related Herpes Zoster compared to regular drugs.
2022 Evidence-Based Complementary and Alternative Medicine Traditional Chinese Medicine for HIV-Associated Acute Herpes Zoster: A Systematic Review and Meta-Analysis of Randomized Trials Jiang Y, Zheng RX, Yu ZY, Zhang XW, Li J, Lan HD, et al.
Systematic Review Shingles
The review began by searching nine electronic databases for randomized controlled trials focused on the use of traditional Chinese medicine in treating HIV-associated Herpes Zoster. Two independent authors extracted data on interventions and outcomes, and the Cochrane risk-of-bias tool was used to evaluate the quality of the trials. Meta-analyses were subsequently performed using specific software.
Results of the review showed that in general, the use of Chinese herbal medicine resulted in lower pain intensity and shorter herpes-related pain duration. Additionally, patients treated with this type of medicine and combined treatments recorded lower incidences of postherpetic neuralgia. The cure rate, defined as the complete absence of pain and herpes, also significantly improved with acupuncture and Chinese herbal medicine, compared to regular drugs. Notably, four trials reported on side effects, and no severe adverse events were mentioned.
Review Articles
Review articles summarise and critically evaluate the current state of research on a specific topic or field by synthesising multiple primary research studies.
Effects and safety of Chinese herbal medicine on inflammatory biomarkers in cardiovascular diseases: A systematic review and meta-analysis of randomized controlled trials
2022 Aug 16 Frontiers in Cardiovascular Medicine Li M, Zhou IW, Trevillyan J, Hearps AC, Zhang AL, Jaworowski A
Systematic Review Meta-Analysis Cardiovascular DiseaseCan't find journal cover —Adrian Y 1 Mar 2023
Cannot import metadata without author field filled —Adrian Y 1 Mar 2023
The Anti-Viral Activity of Prunella vulgaris: A Narrative Review
2022 Jul 01 Integrative Medicine Reports Mak WCK, Walsh S
investigators found that polysaccharides, polyphenolics, triterpenoic acids, and essential oils in P. vulgaris were potent to be anti-viral. The most frequently investigated viral types were HIV, HSV, and influenza virus, to which P. vulgaris extracts were found to be effective. P. vulgaris extracts exhibited good anti-viral activities. However, there is difficulty in producing a collective, summarized, and quantitative analysis from the reviewed articles to the anti-viral effects of P. vulgaris due to the complexity and diverse focus of investigations reported.
Review Article AntiviralTraditional Chinese Medicine for HIV-Associated Acute Herpes Zoster: A Systematic Review and Meta-Analysis of Randomized Trials
2022 Feb 18 Evidence-Based Complementary and Alternative Medicine Jiang Y, Zheng RX, Yu ZY, Zhang XW, Li J, Lan HD, et al.
Systematic Review Meta-Analysis HIV ShinglesTraditional Chinese medicine, including acupuncture, can provide superior pain relief and faster recovery for HIV-related Herpes Zoster compared to regular drugs.
Role of traditional Chinese medicine in incomplete immune reconstitution of HIV/AIDS: a review
2022 Jan Traditional Medicine Research Ji SX, Zhang HY, Wan TJ, Wen L, Feng QS
In conclusion, highly active antiretroviral therapy (HAART) is still the most effective treatment for HIV/AIDS, but it cannot completely achieve immunological reconstruction. Because of the outstanding advantages of TCM in regulating immunity, it is usually chosen as a supplementary treatment for incomplete immune reconstitution (IIR) in China.
Review Article Immunity AIDSChinese herbal medicine for incomplete immune reconstruction in patients with AIDS undergoing antiretroviral treatment: A systematic review of randomized trials
2021 Oct Journal of Traditional Chinese Medical Sciences Shen C, Li J, Lian Y, Lan H, Pu F, Zhang W, et al.
Jianpi Yiqi medicinal paste, Wenshen Jianpi granules, Shenling Fuzheng capsules, Aikeqing granules, Guipi decoction, and TGTs may be effective in increasing CD4+ within 12 months, and Mianyi No.2 granules (JT) and Chinese medicine granules may show long-term effects.
Systematic Review Chinese Herbal Medicine AIDS ImmunityClinical Trials
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Presentation Slides
Network Pharmacology
Gold kiwifruit extracts contained different bioactive materials which showed selective cytotoxic activity against human oral tumor cells and displayed anti-HIV, antioxidant, and antibacterial activities.
Motohashi N, Shirataki Y, Kawase M, Tani S, Sakagami H, Satoh K, Kurihara T, Nakashima H, Mucsi I, Varga A, Molnár J
Systematic Review
Traditional Chinese medicine, including acupuncture, can provide superior pain relief and faster recovery for HIV-related Herpes Zoster compared to regular drugs.
Jiang Y, Zheng RX, Yu ZY, Zhang XW, Li J, Lan HD, Qiao SY, Han M, Cao HJ, Robinson N, Liu JP
Executive Summary
Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for HIV" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.
Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for HIV" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.
Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for HIV" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.
A Network Pharmacology published in 2023 in the journal Journal of Ethnopharmacology found that Gold kiwifruit extracts contained different bioactive materials which showed selective cytotoxic activity against human oral tumor cells and displayed anti-HIV, antioxidant, and antibacterial activities. The methodology involved stepwise extraction of gold kiwifruit with hexane, acetone, methanol, and 70% methanol; the extracts were then fractionated using silica gel and ODS column chromatographies to examine their biological activities. Different fractions like H1, H2 (from the hexane extract), A1, A2 (from the acetone extract), and M2 (from the methanol extract) were tested, as well as more hydrophilic fractions from the 70% methanol extract. In the discussion of the results, fractions H1, H2, A1, A2 and M2 displayed notable cytotoxic activity against human oral tumor cell lines, with these showing more sensitivity compared to human gingival fibroblasts. The hydrophilic fractions from the 70% methanol extract demonstrated higher anti-HIV activity, radical generation, and oxygen scavenging activity. However, the antibacterial activity of these fractions was generally lower than that of the more lipophilic (hexane, acetone, methanol) extracts, indicating no distinct antimicrobial action. Interestingly, all fractions were inactive against Helicobacter pylori.
A Systematic Review published in 2022 in the journal Evidence-Based Complementary and Alternative Medicine found that Traditional Chinese medicine, including acupuncture, can provide superior pain relief and faster recovery for HIV-related Herpes Zoster compared to regular drugs. The review began by searching nine electronic databases for randomized controlled trials focused on the use of traditional Chinese medicine in treating HIV-associated Herpes Zoster. Two independent authors extracted data on interventions and outcomes, and the Cochrane risk-of-bias tool was used to evaluate the quality of the trials. Meta-analyses were subsequently performed using specific software. Results of the review showed that in general, the use of Chinese herbal medicine resulted in lower pain intensity and shorter herpes-related pain duration. Additionally, patients treated with this type of medicine and combined treatments recorded lower incidences of postherpetic neuralgia. The cure rate, defined as the complete absence of pain and herpes, also significantly improved with acupuncture and Chinese herbal medicine, compared to regular drugs. Notably, four trials reported on side effects, and no severe adverse events were mentioned.
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Can't find journal cover —Adrian Y 1 Mar 2023
Cannot import metadata without author field filled —Adrian Y 1 Mar 2023