Lower Urinary Tract Symptoms

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Chinese Medicine Research Hub

Meta-Analysis

Pumpkin seed extract treatment could potentially offer symptomatic relief for patients experiencing moderate lower urinary tract symptoms suggestive of benign prostate hyperplasia.

2022 Clinical Phytoscience Beneficial effects of pumpkin seed soft extract on lower urinary tract symptoms and quality of life in men with benign prostatic hyperplasia: a meta-analysis of two randomized, placebo-controlled trials over 12 months
Vahlensieck W, Heim S, Patz B, Sahin K

Chinese Medicine Research Hub

Clinical Study

Chinese herbal medicine might improve lower urinary tract symptoms in patients with benign prostatic hyperplasia.

2020 Journal of the Chinese Medical Association The effects of a Chinese herbal medicine (VGHBPH0) on patients with benign prostatic hyperplasia: A pilot study
Yeh HF, Li TF, Tsai CH, Wu PW, Huang YH, Huang WJ, Chen FJ, Hwang SJ, Chen FP, Wu TP

Chinese Medicine Research Hub

Randomised Controlled Trial

Pumpkin seed treatment can potentially cause a significant reduction in symptoms of benign prostatic hyperplasia in men aged 50 to 80.

2014 Urologia Internationalis Effects of Pumpkin Seed in Men with Lower Urinary Tract Symptoms due to Benign Prostatic Hyperplasia in the One-Year, Randomized, Placebo-Controlled GRANU Study
Vahlensieck W, Theurer C, Pfitzer E, Patz B, Banik N, Engelmann U

Executive Summary

Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Lower Urinary Tract Symptoms" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.

Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Lower Urinary Tract Symptoms" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.

Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Lower Urinary Tract Symptoms" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.

A Meta-Analysis published in 2022 in the journal Clinical Phytoscience found that Pumpkin seed extract treatment could potentially offer symptomatic relief for patients experiencing moderate lower urinary tract symptoms suggestive of benign prostate hyperplasia. The study methodology involved a meta-analysis of two separate studies that were randomized and placebo-controlled, focusing on the effectiveness of pumpkin seed extract in addressing urinary tract symptoms indicative of benign prostate hyperplasia. The participants included in these studies were those patients whose International Prostate Symptom Score was 13 points or higher at the baseline. The method of analysis involved assessing the response rates of patients and the improvement in prostate symptom scores at a 12-month follow-up. The discussion of results revealed that the response rates in the group receiving pumpkin seed extract were marginally higher than that of the placebo group, giving pumpkin seed extract a slight edge. Additionally, there was a minor difference observed in the change from the baseline to 12-month Prostate Symptom Score in favour of pumpkin seed extract. The meta-analysis in general indicates that a treatment involving pumpkin seed extract may result in symptomatic relief for patients suffering from moderate urinary tract symptoms associated with benign prostate hyperplasia.

A Clinical Study published in 2020 in the journal Journal of the Chinese Medical Association found that Chinese herbal medicine might improve lower urinary tract symptoms in patients with benign prostatic hyperplasia. In the conducted single-arm pilot study, twenty patients with benign prostatic hyperplasia were instructed to take the investigated Chinese herbal medicine three times a day for 8 weeks, coupled with their ongoing Western medicine treatment. Scheduled follow-ups were completed, with patients completing questionnaires such as the international prostate symptoms scores, aging male symptoms score, and international index of erectile function, along with a questionnaire of traditional Chinese medicine body constitution. Diagnostic tools like uroflowmetry and sonography were utilized to measure changes in urine flow velocity and post-voiding residual urine volume over the study span. The results of the study showed a significant decrease in the total prostate symptoms scores post 8 weeks of Chinese herbal medicine treatment, indicating an improvement in the patients' condition. Additionally, this study found a decrease in specific subscores measuring voiding and incomplete emptying. Further to this, a declining trend was also observed in post-voiding residual urine volume, suggesting positive impacts of Chinese herbal medicine on the patients' urinary symptoms.

A Randomised Controlled Trial published in 2014 in the journal Urologia Internationalis found that Pumpkin seed treatment can potentially cause a significant reduction in symptoms of benign prostatic hyperplasia in men aged 50 to 80. In the GRANU study, 1,431 men aged 50-80 years, exhibiting symptoms of benign prostatic hyperplasia, were assigned randomly to one of three groups: those receiving pumpkin seeds, capsules filled with pumpkin seed extract, and a placebo group. The primary criterion for response was measured by a reduction in the International Prostate Symptom Score (IPSS) after 12 months. The secondary outcomes were focused around the quality of life in relation to the IPSS, individual items on the IPSS and diary-recorded nocturia. After a year, there was no statistical difference observed between the group taking pumpkin seed extract and the placebo group. However, the group treated with pumpkin seed showed a significant descriptive difference when compared with the placebo group. The treatment was well tolerated overall and showed a clinically relevant reduction in the IPSS among the men with benign prostatic hyperplasia who were treated with pumpkin seed for 12 months.

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