Rhinosinusitis
Recent Insights
Chinese Herbal Medicines may help with chronic sinusitis and acute rhinosinusitis symptoms with LDXGT and modified CEZS working well, especially for CRS.
Chinese Herbal Medicine Rhinosinusitis
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Research Articles
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Orally administered Chinese herbal therapy to assist post-surgical recovery for chronic rhinosinusitis—A systematic review and meta-analysis
2023 Oct 05 PLOS One Cui J, Lin W, May BH, Luo Q, Worsnop C, Zhang AL, et al.
Meta-Analysis Systematic Review Chronic RhinosinusitisOral Chinese herbal medicines appear to enhance recovery when used as supplements to conventional treatment after sinus surgery.
Chinese herbal therapy in the management of rhinosinusitis—A systematic review and meta-analysis
2022 Dec 01 PLOS One Cui J, Lin W, May BH, Luo Q, Worsnop C, Zhang AL, et al.
Systematic Review Meta-Analysis Rhinosinusitis Chinese Herbal MedicineChinese Herbal Medicines may help with chronic sinusitis and acute rhinosinusitis symptoms with LDXGT and modified CEZS working well, especially for CRS.
Acupuncture for the Treatment of Chronic Rhinosinusitis: A PRISMA-Compliant Systematic Review and Meta-Analysis
2022 Aug 31 Evidence-Based Complementary and Alternative Medicine Lee B, Kwon CY, Park MY
Systematic Review Meta-Analysis Acupuncture Sinusitis Chronic RhinosinusitisAcupuncture, either solo or alongside conventional treatment, results in a significant improvement in symptoms and quality of life for chronic rhinosinusitis sufferers.
Alternative therapies for chronic rhinosinusitis: A review
2020 Oct 06 Ear, Nose & Throat Journal Griffin AS, Cabot P, Wallwork B, Panizza B
We found that while many of the alternative therapies we reviewed might have a firm basis in science, they lack any clinical ev-idence to support their use specifically for chronic rhinosinus-itis (CRS).
Review ArticleA systematic review of randomized controlled trials with herbal medicine on chronic rhinosinusitis
2017 Nov 12 Phytotherapy Research Anushiravani M, Bakhshaee M, Taghipour A, Naghedi-Baghdar H, Farshchi MK, Hoseini SS, et al.
The results of this trials showed that this special medicinal plants may be effective in the treatment of CRS. No serious reactions were reported during the administration of herbal remedies in the 4 studies.
Systematic Review Chronic RhinosinusitisResearch Insights
Insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.
Oral Chinese herbal medicines appear to enhance recovery when used as supplements to conventional treatment after sinus surgery.
2023 PLOS One Orally administered Chinese herbal therapy to assist post-surgical recovery for chronic rhinosinusitis—A systematic review and meta-analysis Cui J, Lin W, May BH, Luo Q, Worsnop C, Zhang AL, et al.
Meta-Analysis Chronic Rhinosinusitis
This study systematically reviews and conducts a meta-analysis of randomised controlled trials, gathered from a wide range of nine databases and clinical trial registries, to evaluate the impact of orally administered Chinese herbal medicines (CHMs) on the post-surgical management of chronic rhinosinusitis. The participants across these trials included adults and children diagnosed with sinusitis or rhinosinusitis, who had undergone surgery. The added interventions were orally consumed CHMs post-surgery in tandem with traditional post-surgery management. The control groups received only the conventional management without CHMs.
The results from a variety of measures including Sino-Nasal Outcome Test, visual analogue scales, various computed tomography scores, and mucociliary transport rates showed greater improvements in the group consuming oral CHMs in addition to the post-surgery treatment, versus the control. Particularly, enhancements were noticeable at follow-up stages after the end of treatment. However, the reporting of adverse events was incomplete across the trials. The study also found that the quality of the studies and their reporting varied, with many studies not being blinded and some results showing substantial heterogeneity.
Chinese Herbal Medicines may help with chronic sinusitis and acute rhinosinusitis symptoms with LDXGT and modified CEZS working well, especially for CRS.
2022 PLOS One Chinese herbal therapy in the management of rhinosinusitis—A systematic review and meta-analysis Cui J, Lin W, May BH, Luo Q, Worsnop C, Zhang AL, et al.
Systematic Review Chinese Herbal Medicine
The review assessed the effectiveness of Chinese herbal medicines (CHMs) in treating chronic rhinosinusitis (CRS) and acute rhinosinusitis (ARS). It found that certain CHMs showed potential in improving CRS symptoms and measures related to sinus health, with the best evidence for LDXGT and modified CEZS formulas. However, more blinded randomized controlled trials are needed to confirm these findings.
Acupuncture, either solo or alongside conventional treatment, results in a significant improvement in symptoms and quality of life for chronic rhinosinusitis sufferers.
2022 Evidence-Based Complementary and Alternative Medicine Acupuncture for the Treatment of Chronic Rhinosinusitis: A PRISMA-Compliant Systematic Review and Meta-Analysis Lee B, Kwon CY, Park MY
Systematic Review Acupuncture Chronic Rhinosinusitis Sinusitis
To evaluate the effectiveness of acupuncture in treating chronic rhinosinusitis, this study utilized 10 randomized controlled clinical trials, found through searching electronic databases. Through these trials, the posttreatment severity of chronic rhinosinusitis was measured, primarily focusing on the Total Effective Rate and patient ratings on the Visual Analogue Scale.
From the analysis of the trial data, it was revealed that acupuncture, when used alone or in combination with conventional treatment methods, led to significant improvements in the severity of chronic rhinosinusitis symptoms and the quality of life of patients. This was indicated by enhanced ratings on the Visual Analogue Scale and the Total Effective Rate. It was also noted that the incidence of adverse events was similar across treatment methods. Despite these promising results, the researchers found a high degree of clinical heterogeneity across the included trials, as well as generally moderate-to-low quality of evidence.
Review Articles
Review articles summarise and critically evaluate the current state of research on a specific topic or field by synthesising multiple primary research studies.
Orally administered Chinese herbal therapy to assist post-surgical recovery for chronic rhinosinusitis—A systematic review and meta-analysis
2023 Oct 05 PLOS One Cui J, Lin W, May BH, Luo Q, Worsnop C, Zhang AL, et al.
Meta-Analysis Systematic Review Chronic RhinosinusitisOral Chinese herbal medicines appear to enhance recovery when used as supplements to conventional treatment after sinus surgery.
Chinese herbal therapy in the management of rhinosinusitis—A systematic review and meta-analysis
2022 Dec 01 PLOS One Cui J, Lin W, May BH, Luo Q, Worsnop C, Zhang AL, et al.
Systematic Review Meta-Analysis Rhinosinusitis Chinese Herbal MedicineChinese Herbal Medicines may help with chronic sinusitis and acute rhinosinusitis symptoms with LDXGT and modified CEZS working well, especially for CRS.
Efficacy and safety of traditional Chinese medicine nasal irrigation on chronic rhinosinusitis recovery after endoscopic sinus surgery: A protocol for a systematic review and meta-analysis
2022 Aug 01 PLOS One Yang Y, Sun Y, Xiang F, Zhang M, Fu L, Zhang Q
This protocol is suitable for evaluating the effectiveness and safety of TCM nasal rinse for chronic rhinosinusitis (CRS) recovery after endoscopic sinus surgery (ESS), and can provide corresponding evidence-based medical evidence.
Meta-Analysis Systematic Review Study Protocol Respiratory Conditions Chronic RhinosinusitisAcupuncture for the Treatment of Chronic Rhinosinusitis: A PRISMA-Compliant Systematic Review and Meta-Analysis
2022 Aug 31 Evidence-Based Complementary and Alternative Medicine Lee B, Kwon CY, Park MY
Systematic Review Meta-Analysis Acupuncture Sinusitis Chronic RhinosinusitisAcupuncture, either solo or alongside conventional treatment, results in a significant improvement in symptoms and quality of life for chronic rhinosinusitis sufferers.
Alternative therapies for chronic rhinosinusitis: A review
2020 Oct 06 Ear, Nose & Throat Journal Griffin AS, Cabot P, Wallwork B, Panizza B
We found that while many of the alternative therapies we reviewed might have a firm basis in science, they lack any clinical ev-idence to support their use specifically for chronic rhinosinus-itis (CRS).
Review ArticleClinical Trials
Clinical trials are research studies that involve people and are conducted to evaluate the safety and efficacy of new treatments or interventions, such as drugs, medical devices, or behavioural therapies.
Study Protocols
Published study protocols are detailed plans that outline the objectives, methodology, statistical analyses, and organisation of a research study that have been made publicly available for others to review and use as a reference.
Efficacy and safety of traditional Chinese medicine nasal irrigation on chronic rhinosinusitis recovery after endoscopic sinus surgery: A protocol for a systematic review and meta-analysis
2022 Aug 01 PLOS One Yang Y, Sun Y, Xiang F, Zhang M, Fu L, Zhang Q
This protocol is suitable for evaluating the effectiveness and safety of TCM nasal rinse for chronic rhinosinusitis (CRS) recovery after endoscopic sinus surgery (ESS), and can provide corresponding evidence-based medical evidence.
Meta-Analysis Systematic Review Study Protocol Respiratory Conditions Chronic RhinosinusitisEffects of houttuynia cordata thunb. on rhinosinusitis by nasal irrigation
2020 Dec 18 Medicine Wang D, Tian T, Liao C, Liu T, Tang G, Tian L
The results of the systematic review will summarise evidences for the efficacy of nasal irrigation with HC preparation in rhinosinusitis treatment.
Study Protocol Nasal IrrigationSystematic evaluation and meta-analysis of quality and safety of life in patients with chronic rhinosinusitis treated by acupuncture
2020 Feb Medicine Li L, Hu S, Zhu X, Zhu T, Li H
This article summarizes the current evidence base for the quality of life and safety of acupuncture in patients with chronic rhinosinusitis (CRS).
Study Protocol Meta-AnalysisPresentation Slides
Meta-Analysis
Oral Chinese herbal medicines appear to enhance recovery when used as supplements to conventional treatment after sinus surgery.
Cui J, Lin W, May BH, Luo Q, Worsnop C, Zhang AL, Guo X, Lu C, Li Y, Xue CC
Systematic Review
Chinese Herbal Medicines may help with chronic sinusitis and acute rhinosinusitis symptoms with LDXGT and modified CEZS working well, especially for CRS.
Cui J, Lin W, May BH, Luo Q, Worsnop C, Zhang AL, Guo X, Lu C, Li Y, Xue CC
Systematic Review
Acupuncture, either solo or alongside conventional treatment, results in a significant improvement in symptoms and quality of life for chronic rhinosinusitis sufferers.
Lee B, Kwon CY, Park MY
Executive Summary
Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Rhinosinusitis" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.
Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Rhinosinusitis" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.
Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Rhinosinusitis" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.
A Meta-Analysis published in 2023 in the journal PLOS One found that Oral Chinese herbal medicines appear to enhance recovery when used as supplements to conventional treatment after sinus surgery. This study systematically reviews and conducts a meta-analysis of randomised controlled trials, gathered from a wide range of nine databases and clinical trial registries, to evaluate the impact of orally administered Chinese herbal medicines (CHMs) on the post-surgical management of chronic rhinosinusitis. The participants across these trials included adults and children diagnosed with sinusitis or rhinosinusitis, who had undergone surgery. The added interventions were orally consumed CHMs post-surgery in tandem with traditional post-surgery management. The control groups received only the conventional management without CHMs. The results from a variety of measures including Sino-Nasal Outcome Test, visual analogue scales, various computed tomography scores, and mucociliary transport rates showed greater improvements in the group consuming oral CHMs in addition to the post-surgery treatment, versus the control. Particularly, enhancements were noticeable at follow-up stages after the end of treatment. However, the reporting of adverse events was incomplete across the trials. The study also found that the quality of the studies and their reporting varied, with many studies not being blinded and some results showing substantial heterogeneity.
A Systematic Review published in 2022 in the journal PLOS One found that Chinese Herbal Medicines may help with chronic sinusitis and acute rhinosinusitis symptoms with LDXGT and modified CEZS working well, especially for CRS. The review assessed the effectiveness of Chinese herbal medicines (CHMs) in treating chronic rhinosinusitis (CRS) and acute rhinosinusitis (ARS). It found that certain CHMs showed potential in improving CRS symptoms and measures related to sinus health, with the best evidence for LDXGT and modified CEZS formulas. However, more blinded randomized controlled trials are needed to confirm these findings.
A Systematic Review published in 2022 in the journal Evidence-Based Complementary and Alternative Medicine found that Acupuncture, either solo or alongside conventional treatment, results in a significant improvement in symptoms and quality of life for chronic rhinosinusitis sufferers. To evaluate the effectiveness of acupuncture in treating chronic rhinosinusitis, this study utilized 10 randomized controlled clinical trials, found through searching electronic databases. Through these trials, the posttreatment severity of chronic rhinosinusitis was measured, primarily focusing on the Total Effective Rate and patient ratings on the Visual Analogue Scale. From the analysis of the trial data, it was revealed that acupuncture, when used alone or in combination with conventional treatment methods, led to significant improvements in the severity of chronic rhinosinusitis symptoms and the quality of life of patients. This was indicated by enhanced ratings on the Visual Analogue Scale and the Total Effective Rate. It was also noted that the incidence of adverse events was similar across treatment methods. Despite these promising results, the researchers found a high degree of clinical heterogeneity across the included trials, as well as generally moderate-to-low quality of evidence.
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