Mulberry
Also known as: Sang Ye
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Research Articles
Published research studies are articles that present the findings of original research that has undergone a peer-review process and has been made publicly available in scholarly journals, books or other media.
Goji berry leaf exerts a comparable effect against colitis and microbiota dysbiosis to its fruit in dextran-sulfate-sodium-treated mice
2023 Jan Food & Function Yu C, Chen Y, Ahmadi S, Wu D, Wu J, Ding T, et al.
Experimental Study Animal Study Anti-Inflammatory Goji Berry Leaf Gut Microbiota Colitis Anti-ColitisGoji berry leaves have stronger anti-colitis effects than mulberry leaves, ameliorating tissue damage and better regulating inflammatory responses and gut microbiota.
Phytochemistry, bioactivities and future prospects of mulberry leaves: A review
2022 Mar Food Chemistry Ma G, Chai X, Hou G, Zhao F, Meng Q
MLs and their extracts may be a promising treatment option for regulating glucose metabolism and lipid metabolism as well as anticancer effects. The dominant compounds responsible for the pharmacological effects of resisting oxidation, reducing blood sugar and lipids, resisting cancer and resisting inflammation in MLs include phenols, flavonoids, polysaccharides and alkaloids. Furthermore, ML suggests ability to inhibit multiple oxidase as well as anti-diabetic effects however more research is needed to yield stronger suggestions
Review Article Sang Ye
Mulberry leaf (Morus alba L.): A review of its potential influences in mechanisms of action on metabolic diseases
2022 Jan Pharmacological Research Zhang R, Zhang Q, Zhu S, Liu B, Liu F, Xu Y
ML are widely used for lipid metabolism and sugar metabolism therapy in a multi-component and multitargeted manner. Overall, ML can be used for treating diabetes by reducing IR, protecting islet cells and regulating glucose-metabolism. For dyslipidemia, there are three strategies including (1) inhibiting fat synthesis and accelerate fat decompose (2) regulating cholesterol synthesis and consumption (3) modulating effects on the antioxidant system. In conclusion, ML as an auxiliary drug can prevent and cure MD. Not only does it reduce high-risk factors for MD, but also minimize the incidence of related complications.
Review Article Sang Ye
The Mulberry (Morus alba L.) Fruit—A Review of Characteristic Components and Health Benefits
2017 Nov 20 Journal of Agricultural and Food Chemistry Yuan Q, Zhao L
Mulberry fruit contains abundant nutrients and bioactive compounds, and it possesses various pharmacological properties, indicating that it is a potential disease-fighting food for the prevention or treatment of chronic illness. However, there are still important gaps in our knowledge regarding the phytochemicals and biological activities of mulberry fruit.
Review Article Mulberry Sang YeResearch Insights
Insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.
Goji berry leaves have stronger anti-colitis effects than mulberry leaves, ameliorating tissue damage and better regulating inflammatory responses and gut microbiota.
2023 Food & Function Goji berry leaf exerts a comparable effect against colitis and microbiota dysbiosis to its fruit in dextran-sulfate-sodium-treated mice Yu C, Chen Y, Ahmadi S, Wu D, Wu J, Ding T, et al.
Experimental Study Anti-Colitis Anti-Inflammatory Colitis
The research entailed a comparative study conducted on goji berry and mulberry leaves versus their respective fruits. To determine their anti-colitis effects, the experiment was administered to C57BL/6N mice that had been induced with colitis through dextran-sulfate-sodium. Through the utilization of measures such as ELISA and western blotting analysis, researchers were able to observe how each leaf versus its corresponding fruit ameliorated colitic symptoms, tissue damage, and was able to influence the overproduction of certain pro-inflammatory cytokines.
The results showed that both the goji berry leaf and fruit significantly reduced symptoms of colitis and improved tissue damage while the mulberry leaf did not show similar improvements. The goji berry leaf exhibited the strongest performance in restraining the overproduction of pro-inflammatory cytokines and further repairing the damaged colonic barrier. It also effectively adjusted gut microbiota equilibrium by increasing beneficial bacteria and decreasing harmful ones. The berries and leaves similarly restored certain dietary fibers to alleviate inflammation, but the mulberry leaf did not achieve this for butyrate. This is the first report to provide a comprehensive contrast of anti-colitis effects between the leaves and fruits of goji and mulberry.
Review Articles
Review articles summarise and critically evaluate the current state of research on a specific topic or field by synthesising multiple primary research studies.
Phytochemistry, bioactivities and future prospects of mulberry leaves: A review
2022 Mar Food Chemistry Ma G, Chai X, Hou G, Zhao F, Meng Q
MLs and their extracts may be a promising treatment option for regulating glucose metabolism and lipid metabolism as well as anticancer effects. The dominant compounds responsible for the pharmacological effects of resisting oxidation, reducing blood sugar and lipids, resisting cancer and resisting inflammation in MLs include phenols, flavonoids, polysaccharides and alkaloids. Furthermore, ML suggests ability to inhibit multiple oxidase as well as anti-diabetic effects however more research is needed to yield stronger suggestions
Review Article Sang YeMulberry leaf (Morus alba L.): A review of its potential influences in mechanisms of action on metabolic diseases
2022 Jan Pharmacological Research Zhang R, Zhang Q, Zhu S, Liu B, Liu F, Xu Y
ML are widely used for lipid metabolism and sugar metabolism therapy in a multi-component and multitargeted manner. Overall, ML can be used for treating diabetes by reducing IR, protecting islet cells and regulating glucose-metabolism. For dyslipidemia, there are three strategies including (1) inhibiting fat synthesis and accelerate fat decompose (2) regulating cholesterol synthesis and consumption (3) modulating effects on the antioxidant system. In conclusion, ML as an auxiliary drug can prevent and cure MD. Not only does it reduce high-risk factors for MD, but also minimize the incidence of related complications.
Review Article Sang YeThe Mulberry (Morus alba L.) Fruit—A Review of Characteristic Components and Health Benefits
2017 Nov 20 Journal of Agricultural and Food Chemistry Yuan Q, Zhao L
Mulberry fruit contains abundant nutrients and bioactive compounds, and it possesses various pharmacological properties, indicating that it is a potential disease-fighting food for the prevention or treatment of chronic illness. However, there are still important gaps in our knowledge regarding the phytochemicals and biological activities of mulberry fruit.
Review Article Mulberry Sang YePresentation Slides
Goji berry leaves have stronger anti-colitis effects than mulberry leaves, ameliorating tissue damage and better regulating inflammatory responses and gut microbiota.
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