Anti-Apoptotic
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Bananas and plantains contain compounds with anti-inflammatory, anti-apoptotic, and antioxidative properties that hold promise for potentially reversing neurological disorders.
Anti-Apoptotic Anti-Inflammatory Antioxidant
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Suitability of Banana and Plantain Fruits in Modulating Neurodegenerative Diseases: Implicating the In Vitro and In Vivo Evidence from Neuroactive Narratives of Constituent Biomolecules
2022 Jul 29 Foods Oyeyinka BO, Afolayan AJ
Anti-Inflammatory Neurodegenerative Diseases Antioxidant Apple Anti-Apoptotic Banana PlantainBananas and plantains contain compounds with anti-inflammatory, anti-apoptotic, and antioxidative properties that hold promise for potentially reversing neurological disorders.
Honey Bee Products: Preclinical and Clinical Studies of Their Anti-inflammatory and Immunomodulatory Properties
2022 Jan 03 Frontiers in Nutrition El-Seedi HR, Eid N, Abd El-Wahed AA, Rateb ME, Afifi HS, Algethami AF, et al.
Bee products, including propolis, royal jelly, honey, bee venom, and bee pollen, show potential therapeutic effects in regulating inflammatory mediator production, improving immune response, and acting as anti-inflammatory, immune protective, antioxidant, anti-apoptotic, and antimicrobial agents.
Review ArticleMechanisms and Efficacy of Chinese Herbal Medicines in Chronic Kidney Disease
2021 Mar 29 Frontiers in Pharmacology Zhao M, Yu Y, Wang R, Chang M, Ma S, Qu H, et al.
Review Article Chinese Herbal MedicineChinese herbal medicines may improve treatment for those with chronic kidney disease, due to their anti-inflammatory, antioxidative, anti-apoptotic, autophagy-mediated, and antifibrotic effects.
Chrysanthemi Flosextract alleviated acetaminophen-induced rat liver injury via inhibiting oxidative stress and apoptosis based on network pharmacology analysis
2021 Jan 01 Pharmaceutical Biology Zhou Y, Wang C, Kou J, Wang M, Rong X, Pu X, et al.
Bianliang ziyu flower ethanol extract (BZE) demonstrated hepatoprotective effects in APAP-induced rats by alleviating liver pathological changes, reducing serum AST and ALT levels, and exhibiting antioxidant and anti-apoptotic activities. BZE (440 mg/kg) significantly reduced ROS levels, upregulated SOD and GSH, activated p-AMPK, p-GSK3β, HO-1, and NQO1, promoted nuclear translocation of Nrf2, inhibited apoptosis through the PI3K–Akt pathway, and restored mitochondrial biogenesis, suggesting its potential as a liver-protecting agent.
Experimental Study Network Pharmacology Drug-Induced Liver Injury Chrysanthemum Acetaminophen Liver InjuryLycopene and Vascular Health
2018 May 23 Frontiers in Pharmacology Mozos, I., Stoian, D., Caraba, A., et al.
Review ArticleLycopene may improve vascular function and contributes to the primary and secondary prevention of cardiovascular disorders.
Research Insights
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Bananas and plantains contain compounds with anti-inflammatory, anti-apoptotic, and antioxidative properties that hold promise for potentially reversing neurological disorders.
2022 Foods Suitability of Banana and Plantain Fruits in Modulating Neurodegenerative Diseases: Implicating the In Vitro and In Vivo Evidence from Neuroactive Narratives of Constituent Biomolecules Oyeyinka BO, Afolayan AJ
Anti-Inflammatory Antioxidant Apple
The methodology of the study revolved around scrutinizing the bioactive properties found in bananas and plantains. Researchers pinpointed various neuroprotective mechanisms within commonly consumed fruits, specifically bananas and plantains. The study examined protein expression regulation and targeted specific gene pathways, including nuclear and tumor necrosis factors, extracellular signal-regulated and mitogen-activated protein kinases, activator protein-1, and the glial fibrillary acidic protein. In their investigations, they also considered the underutilized peel components of these fruits.
The results suggest that the multitude of bioactive compounds found in both the pulp and peels of bananas and plantains perform a variety of beneficial neuroprotective activities. These range from acting as antioxidants, preventing cell death (anti-apoptotic), and reducing inflammation (anti-inflammatory), to directly influencing the functionality of the nervous system (neuromodulatory). This discovery implicates plant-based foods, specifically bananas and plantains, as potentially significant substances in combating, halting, or mitigating the pathological mechanisms underlying neurodegenerative disorders.
Chinese herbal medicines may improve treatment for those with chronic kidney disease, due to their anti-inflammatory, antioxidative, anti-apoptotic, autophagy-mediated, and antifibrotic effects.
2021 Frontiers in Pharmacology Mechanisms and Efficacy of Chinese Herbal Medicines in Chronic Kidney Disease Zhao M, Yu Y, Wang R, Chang M, Ma S, Qu H, et al.
Review Article Chinese Herbal Medicine
The methodology of the research entailed a comprehensive review of peer-reviewed English-language journals that focus on the potential benefits of Chinese herbal medicines (CHMs) in treating kidney disease. The primary factors investigated were the anti-inflammatory, antioxidative, anti-apoptotic, autophagy-mediated, and antifibrotic properties of CHMs that are commonly used in managing kidney disease. The review also incorporated newly published clinical trials and meta-analyses within this field.
The results of the review found that CHMs have multiple beneficial effects, such as anti-inflammatory, antioxidative, anti-apoptotic, autophagy-mediated, and antifibrotic properties. This, backed by well-structured randomized controlled trials and meta-analyses, highlighted that the incorporation of CHMs as an auxiliary with conventional medicines could assist patients suffering from chronic kidney disease. The results, however, noted the limitations on the development of CHMs, like unknown active ingredients, inferior quality, and limited sample sizes of some clinical trials, and questions on CHMs' safety.
Lycopene may improve vascular function and contributes to the primary and secondary prevention of cardiovascular disorders.
2018 Frontiers in Pharmacology Lycopene and Vascular Health Mozos, I., Stoian, D., Caraba, A., et al.
Review Article
The main activity profile of lycopene includes antiatherosclerotic, antioxidant, anti-inflammatory, antihypertensive, antiplatelet, anti-apoptotic, and protective endothelial effects, the ability to improve the metabolic profile, and reduce arterial stiffness. In this context, lycopene has been shown in numerous studies to exert a favorable effect in patients with subclinical atherosclerosis, metabolic syndrome, hypertension, peripheral vascular disease, stroke and several other cardiovascular disorders, although the obtained results are sometimes inconsistent, which warrants further studies focusing on its bioactivity.
Review Articles
Review articles summarise and critically evaluate the current state of research on a specific topic or field by synthesising multiple primary research studies.
Honey Bee Products: Preclinical and Clinical Studies of Their Anti-inflammatory and Immunomodulatory Properties
2022 Jan 03 Frontiers in Nutrition El-Seedi HR, Eid N, Abd El-Wahed AA, Rateb ME, Afifi HS, Algethami AF, et al.
Bee products, including propolis, royal jelly, honey, bee venom, and bee pollen, show potential therapeutic effects in regulating inflammatory mediator production, improving immune response, and acting as anti-inflammatory, immune protective, antioxidant, anti-apoptotic, and antimicrobial agents.
Review ArticleMechanisms and Efficacy of Chinese Herbal Medicines in Chronic Kidney Disease
2021 Mar 29 Frontiers in Pharmacology Zhao M, Yu Y, Wang R, Chang M, Ma S, Qu H, et al.
Review Article Chinese Herbal MedicineChinese herbal medicines may improve treatment for those with chronic kidney disease, due to their anti-inflammatory, antioxidative, anti-apoptotic, autophagy-mediated, and antifibrotic effects.
Lycopene and Vascular Health
2018 May 23 Frontiers in Pharmacology Mozos, I., Stoian, D., Caraba, A., et al.
Review ArticleLycopene may improve vascular function and contributes to the primary and secondary prevention of cardiovascular disorders.
Clinical Trials
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Presentation Slides
Bananas and plantains contain compounds with anti-inflammatory, anti-apoptotic, and antioxidative properties that hold promise for potentially reversing neurological disorders.
Oyeyinka BO, Afolayan AJ
Review Article
Chinese herbal medicines may improve treatment for those with chronic kidney disease, due to their anti-inflammatory, antioxidative, anti-apoptotic, autophagy-mediated, and antifibrotic effects.
Zhao M, Yu Y, Wang R, Chang M, Ma S, Qu H, Zhang Y
Review Article
Lycopene may improve vascular function and contributes to the primary and secondary prevention of cardiovascular disorders.
Mozos, I., Stoian, D., Caraba, A., Malainer, C., Horbańczuk, J. O., & Atanasov, A. G
Executive Summary
Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Anti-Apoptotic" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.
Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Anti-Apoptotic" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.
Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Anti-Apoptotic" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.
A published in 2022 in the journal Foods found that Bananas and plantains contain compounds with anti-inflammatory, anti-apoptotic, and antioxidative properties that hold promise for potentially reversing neurological disorders. The methodology of the study revolved around scrutinizing the bioactive properties found in bananas and plantains. Researchers pinpointed various neuroprotective mechanisms within commonly consumed fruits, specifically bananas and plantains. The study examined protein expression regulation and targeted specific gene pathways, including nuclear and tumor necrosis factors, extracellular signal-regulated and mitogen-activated protein kinases, activator protein-1, and the glial fibrillary acidic protein. In their investigations, they also considered the underutilized peel components of these fruits. The results suggest that the multitude of bioactive compounds found in both the pulp and peels of bananas and plantains perform a variety of beneficial neuroprotective activities. These range from acting as antioxidants, preventing cell death (anti-apoptotic), and reducing inflammation (anti-inflammatory), to directly influencing the functionality of the nervous system (neuromodulatory). This discovery implicates plant-based foods, specifically bananas and plantains, as potentially significant substances in combating, halting, or mitigating the pathological mechanisms underlying neurodegenerative disorders.
A Review Article published in 2021 in the journal Frontiers in Pharmacology found that Chinese herbal medicines may improve treatment for those with chronic kidney disease, due to their anti-inflammatory, antioxidative, anti-apoptotic, autophagy-mediated, and antifibrotic effects. The methodology of the research entailed a comprehensive review of peer-reviewed English-language journals that focus on the potential benefits of Chinese herbal medicines (CHMs) in treating kidney disease. The primary factors investigated were the anti-inflammatory, antioxidative, anti-apoptotic, autophagy-mediated, and antifibrotic properties of CHMs that are commonly used in managing kidney disease. The review also incorporated newly published clinical trials and meta-analyses within this field. The results of the review found that CHMs have multiple beneficial effects, such as anti-inflammatory, antioxidative, anti-apoptotic, autophagy-mediated, and antifibrotic properties. This, backed by well-structured randomized controlled trials and meta-analyses, highlighted that the incorporation of CHMs as an auxiliary with conventional medicines could assist patients suffering from chronic kidney disease. The results, however, noted the limitations on the development of CHMs, like unknown active ingredients, inferior quality, and limited sample sizes of some clinical trials, and questions on CHMs' safety.
A Review Article published in 2018 in the journal Frontiers in Pharmacology found that Lycopene may improve vascular function and contributes to the primary and secondary prevention of cardiovascular disorders. The main activity profile of lycopene includes antiatherosclerotic, antioxidant, anti-inflammatory, antihypertensive, antiplatelet, anti-apoptotic, and protective endothelial effects, the ability to improve the metabolic profile, and reduce arterial stiffness. In this context, lycopene has been shown in numerous studies to exert a favorable effect in patients with subclinical atherosclerosis, metabolic syndrome, hypertension, peripheral vascular disease, stroke and several other cardiovascular disorders, although the obtained results are sometimes inconsistent, which warrants further studies focusing on its bioactivity.
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