Dermatitis
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Research Articles
Published research studies are articles that present the findings of original research that has undergone a peer-review process and has been made publicly available in scholarly journals, books or other media.
Anti-atopic dermatitis effect of a modified Huang-Lian-Jie-Du decoction and its active fraction on 2,4-dinitrobenzene and MC903-induced mouse models
2022 Sep Phytomedicine Wang L, Hu Z, Yang W, Loo SKF, Ip SP, Xian YF, et al.
This study reported for the first time that modified Huang-Lian-Jie-Du Decoction (MHLJDD) and its active fraction could be used as innovative therapeutic agents for atopic dermatitis (AD).
Animal Study Eczema Huang Lian Jie Du Tang
Efficacy and safety of Chinese herbal medicine for atopic dermatitis: Evidence from eight high-quality randomized placebo-controlled trials
2022 Sep 27 Frontiers in Pharmacology Cai X, Sun X, Liu L, Zhou Y, Hong S, Wang J, et al.
Systematic Review EczemaChinese herbal medicine (CHM) improved AD symptoms but had no significant impact on patients' quality of life or IgE levels suggesting CHM's potential as an AD treatment with further research.
The Efficacy and Safety of Acupuncture in the Treatment of Neurodermatitis: A Systematic Review and Meta-Analysis
2022 Sep 01 Evidence-Based Complementary and Alternative Medicine Yang L, Li X, Huang W, Li J, Rao X, Lai Y
Acupuncture is safe and effective in treating neurodermatitis.
Systematic Review Meta-Analysis Neurodermatitis
Indigo Pulverata Levis (Chung-Dae, Persicaria tinctoria) Alleviates Atopic Dermatitis-like Inflammatory Responses In Vivo and In Vitro
2022 Jan 05 International Journal of Molecular Sciences Min GY, Kim JH, Kim TI, Cho WK, Yang JH, Ma JY
Thus, we deduced that IndigoPulverata Levis extract (CHD) is a potential drug candidate for atopic dermatitis (AD) treatment.
Animal Study Qing Dai Eczema
Acupuncture in Dermatology: An Update to a Systematic Review
2021 Jan 01 The Journal of Alternative and Complementary Medicine Hwang J, Lio PA
Systematic ReviewAcupuncture improves clinical outcomes in uremic pruritus, atopic dermatitis, urticaria, and itch.
Research Insights
Insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.
Chinese herbal medicine (CHM) improved AD symptoms but had no significant impact on patients' quality of life or IgE levels suggesting CHM's potential as an AD treatment with further research.
2022 Frontiers in Pharmacology Efficacy and safety of Chinese herbal medicine for atopic dermatitis: Evidence from eight high-quality randomized placebo-controlled trials Cai X, Sun X, Liu L, Zhou Y, Hong S, Wang J, et al.
Systematic Review Eczema
CHM showed benefits in improving AD symptoms, such as itching and skin appearance, compared to placebos. However, it didn't significantly affect patients' quality of life or IgE levels. CHM was safe, with only minor side effects. These findings suggest CHM could be a useful treatment for AD, but more standard guidelines are needed due to variations in herbal ingredients and dosages in different studies.
Acupuncture improves clinical outcomes in uremic pruritus, atopic dermatitis, urticaria, and itch.
2021 The Journal of Alternative and Complementary Medicine Acupuncture in Dermatology: An Update to a Systematic Review Hwang J, Lio PA
Systematic Review
A systematic review published in 2015 found that acupuncture improves outcomes in several dermatological diseases. We performed a systematic review of studies that have been done since then to present updated evidence.
Results showed that acupuncture improves clinical outcomes in uremic pruritus, atopic dermatitis, urticaria, and itch. Acupuncture does not significantly reduce postoperative itch in patients undergoing cesarean section under spinal anesthesia.
While there are some promising studies that support the use of acupuncture for skin diseases, additional large-scale, randomized, sham-controlled trials need to be performed to present consistent high-level evidence of acupuncture's role in dermatology.
Acupuncture may improve symptoms in patients with mild-to-moderate atopic dermatitis.
2018 Complementary Therapies in Medicine Acupuncture improves symptoms in patients with mild-to-moderate atopic dermatitis: A randomized, sham-controlled preliminary trial Smith CA, Armour M, Lee MS, Wang LQ, Hay PJ
Randomised Controlled Trial Eczema Skin Conditions
The SCORing Atopic Dermatitis (SCORAD), VAS (Pruritus), VAS (Insomnia), Patient Oriented Eczema Measure (POEM), Dermatology Life Quality Index (DLQI), and Eczema Area and Severity Index (EASI) were significantly improved in the real acupuncture groups.
There is at least some level I evidence to support the use of acupuncture and acupressure as adjuncts to conventional treatment of atopic dermatitis.
2016 American Journal of Clinical Dermatology Complementary and Alternative Medicine for Atopic Dermatitis: An Evidence-Based Review Vieira BL, Lim NR, Lohman ME, Lio PA.
Systematic Review Eczema Skin Conditions
There is at least some level I evidence to support the use of acupuncture and acupressure, stress-reducing techniques such as hypnosis, massage, and biofeedback, balneotherapy, herbal preparations (with many important caveats), certain botanical oils, oral evening primrose oil, vitamin D supplementation, and topical vitamin B12. Many other therapies either have sufficient data to suggest that they are ineffective, or simply do not have enough evidence to formulate a verdict.
Acupuncture improves outcome measures in the treatment of dermatitis, chloasma, pruritus, urticaria, hyperhidrosis, and facial elasticity.
2015 Journal of Acupuncture and Meridian Studies Acupuncture as a treatment modality in dermatology: a systematic review Ma, C., & Sivamani, R. K.
Systematic Review Cosmetic Facial Acupuncture Eczema Excessive Sweating
Twenty-four studies met inclusion criteria. Among these, 16 were randomized controlled trials, 6 were prospective observational studies, and 2 were case reports. Acupuncture was used to treat atopic dermatitis, urticaria, pruritus, acne, chloasma, neurodermatitis, dermatitis herpetiformis, hyperhidrosis, human papillomavirus wart, breast inflammation, and facial elasticity. In 17 of 24 studies, acupuncture showed statistically significant improvements in outcome measurements compared with placebo acupuncture, alternative treatment options, and no intervention.
Review Articles
Review articles summarise and critically evaluate the current state of research on a specific topic or field by synthesising multiple primary research studies.
Efficacy and safety of Chinese herbal medicine for atopic dermatitis: Evidence from eight high-quality randomized placebo-controlled trials
2022 Sep 27 Frontiers in Pharmacology Cai X, Sun X, Liu L, Zhou Y, Hong S, Wang J, et al.
Systematic Review EczemaChinese herbal medicine (CHM) improved AD symptoms but had no significant impact on patients' quality of life or IgE levels suggesting CHM's potential as an AD treatment with further research.
The Efficacy and Safety of Acupuncture in the Treatment of Neurodermatitis: A Systematic Review and Meta-Analysis
2022 Sep 01 Evidence-Based Complementary and Alternative Medicine Yang L, Li X, Huang W, Li J, Rao X, Lai Y
Acupuncture is safe and effective in treating neurodermatitis.
Systematic Review Meta-Analysis NeurodermatitisAcupuncture in Dermatology: An Update to a Systematic Review
2021 Jan 01 The Journal of Alternative and Complementary Medicine Hwang J, Lio PA
Systematic ReviewAcupuncture improves clinical outcomes in uremic pruritus, atopic dermatitis, urticaria, and itch.
Effectiveness and Safety of Herbal Medicine for Atopic Dermatitis: An Overview of Systematic Reviews
2020 Jul 17 Evidence-Based Complementary and Alternative Medicine Kwon CY, Lee B, Kim S, Lee J, Park M, Kim N
The results suggested that herbal medicine (HM) as a monotherapy or an adjunctive therapy is promising for the treatment of atopic dermatitis (AD).
Review Article EczemaPhellodendri Cortex: A Phytochemical, Pharmacological, and Pharmacokinetic Review
2019 Apr 01 Evidence-Based Complementary and Alternative Medicine Sun Y, Lenon GB, Yang AWH
The compounds of the crude bark of PC and its subspecies have showcased a wide range of pharmacological effects. Pharmacological efficacies of PC are supported by its diverse class of alkaloid, limonoid, phenolic acid, quinic acid, lignan, and flavonoid. Obacunone and obaculactone could be the bioactive compounds for atopic dermatitis management. PC and its subspecies are generally safe to use but extra care is required for certain conditions and group of people.
Review Article Huang BaiClinical Trials
Clinical trials are research studies that involve people and are conducted to evaluate the safety and efficacy of new treatments or interventions, such as drugs, medical devices, or behavioural therapies.
Efficacy and safety of indigo naturalis ointment in Treating Atopic Dermatitis: A randomized clinical trial
2020 Mar Journal of Ethnopharmacology Lin YK, Chang SH, Yang CY, See LC, Lee BH, Shih IH
Indigo naturalis ointment is effective for treating mild to severe atopic dermatitis (AD) topically, and appears to be safe. This is the first clinical trial to provide evidence supporting topical indigo-based AD treatment.
Randomised Controlled TrialAcupuncture improves symptoms in patients with mild-to-moderate atopic dermatitis: A randomized, sham-controlled preliminary trial
2018 Mar 4 Complementary Therapies in Medicine Smith CA, Armour M, Lee MS, Wang LQ, Hay PJ
Randomised Controlled Trial Eczema Skin ConditionsAcupuncture may improve symptoms in patients with mild-to-moderate atopic dermatitis.
Efficacy of a Chinese herbal medicine for the treatment of atopic dermatitis: A randomised controlled study
2015 Oct Complementary Therapies in Medicine Liu J, Mo X, Wu D, Ou A, Xue S, Liu C, et al.
Pei Tu Qing Xin Tang (PTQXT) is effective in decreasing the severity of the disease and improving the quality of life (QOL) in patients with moderate-to-severe atopic dermatitis (AD).
Randomised Controlled Trial Pei Tu Qing Xin TangStudy Protocols
Published study protocols are detailed plans that outline the objectives, methodology, statistical analyses, and organisation of a research study that have been made publicly available for others to review and use as a reference.
The efficacy and safety of Longmu Tang granule for the treatment of atopic dermatitis: study protocol for a single-centred, double-blinded, randomised, placebo-controlled trial
2022 May 09 BMC Complementary Medicine and Therapies Li Y, Shen T, Wang Q, Ma M, Tian F, She Y, et al.
The results of this trial will provide evidence of the efficacy and safety of the Longmu Tang granule and prove its anti-inflammatory action in patients with atopic dermatitis (AD).
Study Protocol Eczema
The herbal drug, Bu-Zhong-Yi-Qi-Tang, for the treatment of atopic dermatitis
2019 Jan Medicine Jeong MK, Kim YE, Kim A, Jung J, Son MJ
Thus, in this study, we will investigate the clinical evidence related to the effectiveness of Bu-Zhong-Yi-Qi-Tang (BZYQT) for treating atopic dermatitis (AD).
Study ProtocolPresentation Slides
Chinese herbal medicine (CHM) improved AD symptoms but had no significant impact on patients' quality of life or IgE levels suggesting CHM's potential as an AD treatment with further research.
Acupuncture improves clinical outcomes in uremic pruritus, atopic dermatitis, urticaria, and itch.
Acupuncture may improve symptoms in patients with mild-to-moderate atopic dermatitis.
There is at least some level I evidence to support the use of acupuncture and acupressure as adjuncts to conventional treatment of atopic dermatitis.
Acupuncture improves outcome measures in the treatment of dermatitis, chloasma, pruritus, urticaria, hyperhidrosis, and facial elasticity.
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