Periodontitis

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Chinese Medicine Research Hub

Review Article

Lemongrass essential oil can effectively treat periodontitis, gingivitis, oral malodour, skin aging, and dandruff, and it is comparable to certain established treatments.

2024 Pharmaceuticals Exploring the Clinical Applications of Lemongrass Essential Oil: A Scoping Review
Kusuma IY, Perdana MI, Vágvölgyi C, Csupor D, Takó M

Chinese Medicine Research Hub

Systematic Review

Green tea treatment has shown potential in improving oral hygiene and gingival health, and reducing periodontitis and caries.

2021 Japanese Dental Science Review Impact of Green Tea (Camellia Sinensis) on periodontitis and caries. Systematic review and meta-analysis
Mazur M, Ndokaj A, Jedlinski M, Ardan R, Bietolini S, Ottolenghi L

Chinese Medicine Research Hub

Randomised Controlled Trial

Morinda citrifolia fruit extract effectively supports bone regeneration and has anti-inflammatory properties in periodontal bone defects.

2021 Journal of the International Society of Physical and Rehabilitation Medicine Evaluation of Morinda citrifolia (noni) fruit extract as a bone regenerative material in the treatment of periodontal intrabony osseous defects: Clinical and cone-beam computed tomography assessment
Sabu BS, Chandrashekar KT, Mishra R, Tripathi VD, Khatri H, Deo A

Chinese Medicine Research Hub

Systematic Review

Honey showed a significant antimicrobial activity against all targeted periopathogen and could be effective in the treatment of periodontal disease.

2020 Journal of Antimicrobial Chemotherapy Antimicrobial activity of honey in periodontal disease: a systematic review
Hbibi A, Sikkou K, Khedid K, El Hamzaoui S, Bouziane A, Benazza D

Executive Summary

Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Periodontitis" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.

Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Periodontitis" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.

Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Periodontitis" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.

A Review Article published in 2024 in the journal Pharmaceuticals found that Lemongrass essential oil can effectively treat periodontitis, gingivitis, oral malodour, skin aging, and dandruff, and it is comparable to certain established treatments. The methodology used in the research followed a scoping review design, which was aimed at identifying, summarizing, and synthesizing existing literature related to the clinical applications of lemongrass essential oil. Three databases, namely PubMed, Web of Science, and Scopus, were utilized, following the PRISMA-ScR guidelines, to find articles published within approximately a 10-year timeframe. The results of the review suggest that patients have received noticeable therapeutic benefits from treatments that were primarily administered oromucosally and topically. It can be deduced that the efficacy of lemongrass essential oil in treating periodontitis, gingivitis, and oral malodour is similar to that of chlorhexidine and doxycycline. Moreover, the oil has demonstrated potential in treating skin conditions such as pityriasis versicolor, preventing skin aging, and having anti-dandruff effects. The diverse range of applications of the oil and its efficacy when compared to established treatments highlight its potential for clinical applications.

A Systematic Review published in 2021 in the journal Japanese Dental Science Review found that Green tea treatment has shown potential in improving oral hygiene and gingival health, and reducing periodontitis and caries. The methodology of this research consisted of systematic literature review focusing on clinical trials that evaluated the impact of green tea on managing periodontitis and caries. Various databases including MedLine (PubMed), Scopus, and the Cochrane Library were utilized for gathering relevant studies. Eighteen suitable studies were selected, encompassing 870 subjects. The results reveal a noticeable positive effect from green tea treatment. This effect was realized in the reduction of gingival index, plaque index, gingival bleeding index and bleeding on probing when compared to a control group. It was also noted that when considered among chlorhexidine control groups, green tea showed a slight negative effect. There was additionally a significant positive effect seen in the reduction of clinical attachment level and probing pocket depth with green tea treatment.

A Randomised Controlled Trial published in 2021 in the journal Journal of the International Society of Physical and Rehabilitation Medicine found that Morinda citrifolia fruit extract effectively supports bone regeneration and has anti-inflammatory properties in periodontal bone defects. This study randomized twenty patients who required periodontal regenerative therapy into two groups - an experimental group and a control group. For the control group, open flap debridement alone was used while in the experimental group, the application of Morinda citrifolia fruit extract was coupled with open flap debridement. Clinical aspects such as the gingival index, probing depth of pockets, and relative attachment level were assessed, along with the quantity of bone fill using cone-beam computed tomography at the beginning and after six months. The use of Morinda citrifolia fruit extract in the experimental group resulted in a significant reduction in probing pocket depth and increase in relative attachment level. Furthermore, the extract promoted a higher rate of bone fill in the experimental group compared with the control group, suggesting efficiency in the treatment of intraosseous defects. Additionally, the extract showcased some anti-inflammatory effects, amplifying its potential therapeutic uses.

A Systematic Review published in 2020 in the journal Journal of Antimicrobial Chemotherapy found that Honey showed a significant antimicrobial activity against all targeted periopathogen and could be effective in the treatment of periodontal disease. A total of 1448 publications were found as search results in the screened databases. Sixteen eligible papers were included based on predetermined inclusion criteria. Retained studies included 5 RCTs and 11 in vitro controlled trials. Manuka and multifloral honeys were the most studied varieties. The tested honeys showed a significant antimicrobial action, with different MICs, against eight periopathogens. Four of the five RCTs showed a high RoB, while 4 of the 11 retained in vitro studies showed a medium RoB.

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