Oral Health
Also known as: Oral Disease
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The pomegranate plant has a rich inventory of phytochemical constituents showing pharmacological efficiency in treating cardiovascular and endocrine diseases.
Oral Health
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Research Articles
Published research studies are articles that present the findings of original research that has undergone a peer-review process and has been made publicly available in scholarly journals, books or other media.
Exploring the Clinical Applications of Lemongrass Essential Oil: A Scoping Review
2024 Jan 25 Pharmaceuticals Kusuma IY, Perdana MI, Vágvölgyi C, Csupor D, Takó M
Review Article Lemongrass Oil Dandruff Gingivitis Periodontitis LemongrassLemongrass essential oil can effectively treat periodontitis, gingivitis, oral malodour, skin aging, and dandruff, and it is comparable to certain established treatments.
A systematic and comprehensive review on current understanding of the pharmacological actions, molecular mechanisms, and clinical implications of the genus Eucalyptus
2021 Nov Phytomedicine Plus Chandorkar N, Tambe S, Amin P, Madankar C
Eucalyptus species, especially Eucalyptol, demonstrate significant potential in the treatment and management of various diseases, including respiratory disorders, COVID-19, pain, oral health, infectious diseases, and cancer, as supported by preclinical and clinical studies.
Review Article Eucalyptus Molecular Mechanism Clinical Implication Health Benefits Pharmacologic ActivityTherapeutic Effects of Punica granatum (Pomegranate): An Updated Review of Clinical Trials
2021 Nov 16 Journal of Nutrition and Metabolism Eghbali S, Askari SF, Avan R, Sahebkar A
Review Article Oral HealthThe pomegranate plant has a rich inventory of phytochemical constituents showing pharmacological efficiency in treating cardiovascular and endocrine diseases.
Efficacy and Safety of Modified Yunu-Jian in Patients with Periodontitis: A Meta-Analysis
2021 Apr 26 Evidence-Based Complementary and Alternative Medicine Yuanyuan Yue, Meng Gao, Yanru Deng, Jiemin Shao, Yingguang Sun
Evidence from the meta-analysis suggested that modified Yunu-Jian (mYJ) appeared to be effective and relatively safe for treating periodontitis.
Meta-Analysis Periodontitis Yu Nu Jian
Acupuncture for pain, mandibular function and oral health‐related quality of life in patients with masticatory myofascial pain: A randomised controlled trial
2020 Jul 31 Journal of Oral Rehabilitation Salles‐Neto FT, Paula JS, Romero JGAJ, Almeida‐Leite CM
Although acupuncture was effective in pain reduction, non-specific factors may have influenced mandibular function and oral health-related quality of life improvements in both groups, and this needs to be further addressed.
Randomised Controlled Trial Masticatory Myofascial PainResearch Insights
Insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.
Lemongrass essential oil can effectively treat periodontitis, gingivitis, oral malodour, skin aging, and dandruff, and it is comparable to certain established treatments.
2024 Pharmaceuticals Exploring the Clinical Applications of Lemongrass Essential Oil: A Scoping Review Kusuma IY, Perdana MI, Vágvölgyi C, Csupor D, Takó M
Review Article Dandruff Gingivitis Lemongrass
The methodology used in the research followed a scoping review design, which was aimed at identifying, summarizing, and synthesizing existing literature related to the clinical applications of lemongrass essential oil. Three databases, namely PubMed, Web of Science, and Scopus, were utilized, following the PRISMA-ScR guidelines, to find articles published within approximately a 10-year timeframe.
The results of the review suggest that patients have received noticeable therapeutic benefits from treatments that were primarily administered oromucosally and topically. It can be deduced that the efficacy of lemongrass essential oil in treating periodontitis, gingivitis, and oral malodour is similar to that of chlorhexidine and doxycycline. Moreover, the oil has demonstrated potential in treating skin conditions such as pityriasis versicolor, preventing skin aging, and having anti-dandruff effects. The diverse range of applications of the oil and its efficacy when compared to established treatments highlight its potential for clinical applications.
The pomegranate plant has a rich inventory of phytochemical constituents showing pharmacological efficiency in treating cardiovascular and endocrine diseases.
2021 Journal of Nutrition and Metabolism Therapeutic Effects of Punica granatum (Pomegranate): An Updated Review of Clinical Trials Eghbali S, Askari SF, Avan R, Sahebkar A
Review Article
The researchers set out to review both traditional and scientific applications of P. granatum focusing on its phytochemical content and potential for aiding in drug development. They gathered relevant information through both classic herbal literature and electronic databases, which included renowned platforms such as PubMed, Scopus, and ScienceDirect.
The culmination of traditional and contemporary research showed an array of phytochemical constituents in P. granatum, including polyphenolics, flavonoids, anthocyanosides, alkaloids, lignans, and triterpenes. Randomized controlled trials indicated these constituents demonstrate pharmacological activity, particularly against diseases like diabetes, cardiovascular disease, oral cavity disorders, endocrine disorders, and even cancer. The review, therefore, not only points to the traditional uses of P. granatum but underscores their validation through scientific support.
Green tea catechins-containing mouthwash may potentially be a practical alternative to chlorhexidine due to its efficacy in plaque reduction and minimal side effects.
2020 Journal of Herbal Medicine The Effect of Green Tea on plaque and gingival inflammation: A systematic review Gartenmann SJ, Steppacher SL, von Weydlich Y, Heumann C, Attin T, Schmidlin PR
Systematic Review Gingivitis Green Tea Plaque
The methodology involved an exhaustive literature review of several electronic databases, such as CINAHL, Cochrane Library, MEDLINE, PubMed and Scopus, up until January 2017. This review adhered to the PRISMA criteria, centring the research question around the impact of green tea catechins-containing mouthwash on plaque accumulation and gingival inflammation in patients with gingivitis. Out of the 187 titles identified this way, five were fit for meta-analysis, the subject matter primarily revolving around an Asian population.
The results indicated that both green tea and chlorhexidine (CHX) significantly outperformed a placebo in reducing Plaque Index (PI), with no substantial contrast between the CHX and green tea groups, both in terms of the endpoint and the change from the beginning of the study to its conclusion. However, only minor side effects were associated with the green tea mouthwash. Contrarily to chlorhexidine, this aspect might make green tea mouthwash more suitable for prolonged use. Despite some heterogeneity in the data and potential bias risks, green tea mouthwash remains an interesting, viable alternative worth considering.
Honey showed a significant antimicrobial activity against all targeted periopathogen and could be effective in the treatment of periodontal disease.
2020 Journal of Antimicrobial Chemotherapy Antimicrobial activity of honey in periodontal disease: a systematic review Hbibi A, Sikkou K, Khedid K, El Hamzaoui S, Bouziane A, Benazza D
Systematic Review Antimicrobial Honey Periodontitis
A total of 1448 publications were found as search results in the screened databases. Sixteen eligible papers were included based on predetermined inclusion criteria. Retained studies included 5 RCTs and 11 in vitro controlled trials. Manuka and multifloral honeys were the most studied varieties. The tested honeys showed a significant antimicrobial action, with different MICs, against eight periopathogens. Four of the five RCTs showed a high RoB, while 4 of the 11 retained in vitro studies showed a medium RoB.
Among the health benefits of green tea are: anticarcinogenic, anti-inflammatory, antimicrobial, and antioxidant properties, and benefits in cardiovascular disease and oral health.
2018 Beverages An Update on the Health Benefits of Green Tea Wanda C. Reygaert
Systematic Review
Green tea catechins have proved to be very versatile in providing health benefits. This means that there are potential health benefits for everyone in the consumption of green tea. Even moderate amounts of consumption (drinking 1–2 cups of tea per day) may have benefits. It is a very good thing that it is the second most popular beverage worldwide, as the differences in health in a world without green tea might be significant. There is fortunately a wide variety of research being performed using green tea catechins, and we are starting to see many studies performed using human subjects, as it is extremely important that we are able to show the direct benefits to humans. The expansive repertoire of green tea activity in health is important, especially to those people who live where medical assistance is not generally available or affordable.
Review Articles
Review articles summarise and critically evaluate the current state of research on a specific topic or field by synthesising multiple primary research studies.
Exploring the Clinical Applications of Lemongrass Essential Oil: A Scoping Review
2024 Jan 25 Pharmaceuticals Kusuma IY, Perdana MI, Vágvölgyi C, Csupor D, Takó M
Review Article Lemongrass Oil Dandruff Gingivitis Periodontitis LemongrassLemongrass essential oil can effectively treat periodontitis, gingivitis, oral malodour, skin aging, and dandruff, and it is comparable to certain established treatments.
A systematic and comprehensive review on current understanding of the pharmacological actions, molecular mechanisms, and clinical implications of the genus Eucalyptus
2021 Nov Phytomedicine Plus Chandorkar N, Tambe S, Amin P, Madankar C
Eucalyptus species, especially Eucalyptol, demonstrate significant potential in the treatment and management of various diseases, including respiratory disorders, COVID-19, pain, oral health, infectious diseases, and cancer, as supported by preclinical and clinical studies.
Review Article Eucalyptus Molecular Mechanism Clinical Implication Health Benefits Pharmacologic ActivityTherapeutic Effects of Punica granatum (Pomegranate): An Updated Review of Clinical Trials
2021 Nov 16 Journal of Nutrition and Metabolism Eghbali S, Askari SF, Avan R, Sahebkar A
Review Article Oral HealthThe pomegranate plant has a rich inventory of phytochemical constituents showing pharmacological efficiency in treating cardiovascular and endocrine diseases.
The Effect of Green Tea on plaque and gingival inflammation: A systematic review
2020 Jun Journal of Herbal Medicine Gartenmann SJ, Steppacher SL, von Weydlich Y, Heumann C, Attin T, Schmidlin PR
Systematic Review Gingivitis Green Tea PlaqueGreen tea catechins-containing mouthwash may potentially be a practical alternative to chlorhexidine due to its efficacy in plaque reduction and minimal side effects.
Antimicrobial activity of honey in periodontal disease: a systematic review
2020 Jan 16 Journal of Antimicrobial Chemotherapy Hbibi A, Sikkou K, Khedid K, El Hamzaoui S, Bouziane A, Benazza D
Systematic Review Honey Periodontitis AntimicrobialHoney showed a significant antimicrobial activity against all targeted periopathogen and could be effective in the treatment of periodontal disease.
Clinical Trials
Clinical trials are research studies that involve people and are conducted to evaluate the safety and efficacy of new treatments or interventions, such as drugs, medical devices, or behavioural therapies.
Presentation Slides
Lemongrass essential oil can effectively treat periodontitis, gingivitis, oral malodour, skin aging, and dandruff, and it is comparable to certain established treatments.
The pomegranate plant has a rich inventory of phytochemical constituents showing pharmacological efficiency in treating cardiovascular and endocrine diseases.
Green tea catechins-containing mouthwash may potentially be a practical alternative to chlorhexidine due to its efficacy in plaque reduction and minimal side effects.
Honey showed a significant antimicrobial activity against all targeted periopathogen and could be effective in the treatment of periodontal disease.
Among the health benefits of green tea are: anticarcinogenic, anti-inflammatory, antimicrobial, and antioxidant properties, and benefits in cardiovascular disease and oral health.
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