Allergy
Recent Insights
Honey, traditionally a food item, exhibits therapeutic properties—anti-microbial, anti-inflammatory, anti-cancer, and wound healing—showing promise in managing and preventing allergic diseases, as supported by scientific evidence and clinical studies.
Allergy Asthma Eczema
Consumption of raw milk early in life appears to provide protection against asthma and allergies, regardless of whether children live on farms or in rural, non-farm areas.
Allergy Asthma Raw Milk
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Research Articles
Published research studies are articles that present the findings of original research that has undergone a peer-review process and has been made publicly available in scholarly journals, books or other media.
Chemistry and Bioactivity of Flos Magnoliae, A Chinese Herb for Rhinitis and Sinusitis
2022 Jul 01 Current Medicinal Chemistry Shen Y, Li C, Zhou S, Pang E, Story D, Xue C
A wide range of pharmacological actions of Flos Magnoliae (FM, Chinese name: Xin-yi) have been reported, including anti-allergy, anti-inflammation and anti-microbial activity.
Review Article Xin Yi Rhinitis
Network pharmacology-based analysis of the mechanism of Saposhnikovia divaricata for the treatment of type I allergy
2022 Jun 27 Pharmaceutical Biology Li X, Li H, Wang T, Zhao Y, Shao Y, Sun Y, et al.
Saposhnikovia divaricata could inhibit mast cells, providing a scientific basis for further research and clinical applications of SD in TIA treatment.
Network Pharmacology Type 1 Allergy
Potential Role of Omega-3 Polyunsaturated Fatty Acids in Pediatric Food Allergy
2021 Dec 29 Nutrients Sartorio MUA, Pendezza E, Coppola S, Paparo L, D’Auria E, Zuccotti GV, et al.
Recent evidence suggests an imbalance in the ω-3:ω-6 ratio due to increased intake of ω-6, especially in westernized diets. The critical age groups, such as infants, toddlers, young children, pregnant/lactating women, and fish-allergic patients, may have inadequate ω-3 intake. Preclinical studies with PUFAs supplementation show promising effects in suppressing allergic responses, but clinical study results are conflicting regarding timing, dosages, and the most likely beneficiaries. The review emphasizes the need for more data on the effects of ω-3 PUFAs supplementation in both the general and food-allergic populations.
Review Article Children's Health Food Allergy
Traditional Chinese medicine for food allergy and eczema
2021 Jun Annals of Allergy, Asthma & Immunology Wang Z, Wang ZZ, Geliebter J, Tiwari R, Li XM
TCM has potential as safe and effective therapy for food allergy and eczema. Further research is needed for botanical drug development and to further define the mechanisms of actions.
Review Article Food AllergyVitamin D and Allergy Susceptibility during Gestation and Early Life
2021 Mar 21 Nutrients Briceno Noriega D, Savelkoul HFJ
Our review indicates that a sufficient vitamin D status during gestation and early life can lower the susceptibility to develop an allergy in infants although there remains a need for more causal evidence.
Review Article PregnancyResearch Insights
Insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.
Honey, traditionally a food item, exhibits therapeutic properties—anti-microbial, anti-inflammatory, anti-cancer, and wound healing—showing promise in managing and preventing allergic diseases, as supported by scientific evidence and clinical studies.
2021 Frontiers in Pharmacology The Potential use of Honey as a Remedy for Allergic Diseases: A Mini Review Aw Yong PY, Islam F, Harith HH, Israf DA, Tan JW, Tham CL
Review Article Asthma Eczema Honey
This mini review explores honey's transition from a conventional food to a potential treatment for allergic diseases. Emphasis is placed on its diverse therapeutic properties, particularly its ability to alleviate pathological conditions and regulate inflammatory cell recruitment in cellular and animal models.
Scientific evidence and clinical studies suggest that honey holds potential in relieving allergic symptoms, offering a promising treatment or preventive approach for allergic diseases such as anaphylaxis, asthma, and atopic dermatitis. The review provides valuable insights for considering honey in clinical settings for allergic disease management.
Consumption of raw milk early in life appears to provide protection against asthma and allergies, regardless of whether children live on farms or in rural, non-farm areas.
2020 The Journal of Allergy and Clinical Immunology: In Practice The Beneficial Effect of Farm Milk Consumption on Asthma, Allergies, and Infections: From Meta-Analysis of Evidence to Clinical Trial Brick T, Hettinga K, Kirchner B, Pfaffl MW, Ege MJ
Meta-Analysis Asthma Raw Milk
Whoever did the research carried out a comprehensive literature review, identifying twelve relevant publications from eight unique studies. Their approach involved a meta-analysis to substantiate the protective effect of raw milk consumption in early life, particularly for ages ranging from less than one year old to five years old. They further analyzed the impacts of raw milk on not only asthma but also other ailments such as wheezing, hay fever, allergic rhinitis, and atopic sensitization. Moreover, evidence was provided about the beneficial effects of raw milk for children, both living on the farms and those in rural sectors but not on farms.
Moreover, in the interpretation of results, it was clearly evident that the consumption of raw milk had an independent effect, separate from other farm exposures. In essence, even children not residing on farms theoretically can still gain from the benefits of raw milk consumption. However, they express a strong sense of caution, advocating against the consumption of raw milk due to the possibility of life-threatening infections. Furthermore, the distinction between raw farm milk and industrially processed milk was underlined to highlight differences in cellular components, fat fraction, and heating degrees. Preliminary findings link these characteristics and attributes of raw milk to heat-labile molecules and components found in its fat fraction.
The claimed health benefits of coix include anti-oxidation, anti-cancer, anti-inflammation, anti-allergy, enhancing immunological activity, regulating endocrine functions, anti-obesity, anti-diabetes, gastroprotection, hypolipidemia, and modulating gut microbiota.
2017 Trends in Food Science & Technology Coix: Chemical composition and health effects Fan Zhu
Review Article
Coix seeds contain a range of bioactive components including polysaccharides, proteins, lipids, polyphenols, phytosterols, carotenoids, spiroenone and lactams. The chemical constituents of coix contribute to a range of medical and nutritional benefits. These claimed health benefits include anti-oxidation, anti-cancer, anti-inflammation, anti-allergy, enhancing immunological activity, regulating endocrine functions, anti-obesity, anti-diabetes, gastroprotection, hypolipidemia, and modulating gut microbiota. The bioactivity of coix depends on the varieties as well as the sample preparation methods such as the solvent type. Coix seed is rich in starch and has similar processing properties of other cereals for food formulation. Coix can be further developed as a healthy grain for human consumption.
Review Articles
Review articles summarise and critically evaluate the current state of research on a specific topic or field by synthesising multiple primary research studies.
Chemistry and Bioactivity of Flos Magnoliae, A Chinese Herb for Rhinitis and Sinusitis
2022 Jul 01 Current Medicinal Chemistry Shen Y, Li C, Zhou S, Pang E, Story D, Xue C
A wide range of pharmacological actions of Flos Magnoliae (FM, Chinese name: Xin-yi) have been reported, including anti-allergy, anti-inflammation and anti-microbial activity.
Review Article Xin Yi RhinitisPotential Role of Omega-3 Polyunsaturated Fatty Acids in Pediatric Food Allergy
2021 Dec 29 Nutrients Sartorio MUA, Pendezza E, Coppola S, Paparo L, D’Auria E, Zuccotti GV, et al.
Recent evidence suggests an imbalance in the ω-3:ω-6 ratio due to increased intake of ω-6, especially in westernized diets. The critical age groups, such as infants, toddlers, young children, pregnant/lactating women, and fish-allergic patients, may have inadequate ω-3 intake. Preclinical studies with PUFAs supplementation show promising effects in suppressing allergic responses, but clinical study results are conflicting regarding timing, dosages, and the most likely beneficiaries. The review emphasizes the need for more data on the effects of ω-3 PUFAs supplementation in both the general and food-allergic populations.
Review Article Children's Health Food AllergyTraditional Chinese medicine for food allergy and eczema
2021 Jun Annals of Allergy, Asthma & Immunology Wang Z, Wang ZZ, Geliebter J, Tiwari R, Li XM
TCM has potential as safe and effective therapy for food allergy and eczema. Further research is needed for botanical drug development and to further define the mechanisms of actions.
Review Article Food AllergyVitamin D and Allergy Susceptibility during Gestation and Early Life
2021 Mar 21 Nutrients Briceno Noriega D, Savelkoul HFJ
Our review indicates that a sufficient vitamin D status during gestation and early life can lower the susceptibility to develop an allergy in infants although there remains a need for more causal evidence.
Review Article PregnancyThe Potential use of Honey as a Remedy for Allergic Diseases: A Mini Review
2021 Jan 26 Frontiers in Pharmacology Aw Yong PY, Islam F, Harith HH, Israf DA, Tan JW, Tham CL
Review Article Allergy Asthma Honey EczemaHoney, traditionally a food item, exhibits therapeutic properties—anti-microbial, anti-inflammatory, anti-cancer, and wound healing—showing promise in managing and preventing allergic diseases, as supported by scientific evidence and clinical studies.
Presentation Slides
Honey, traditionally a food item, exhibits therapeutic properties—anti-microbial, anti-inflammatory, anti-cancer, and wound healing—showing promise in managing and preventing allergic diseases, as supported by scientific evidence and clinical studies.
Consumption of raw milk early in life appears to provide protection against asthma and allergies, regardless of whether children live on farms or in rural, non-farm areas.
The claimed health benefits of coix include anti-oxidation, anti-cancer, anti-inflammation, anti-allergy, enhancing immunological activity, regulating endocrine functions, anti-obesity, anti-diabetes, gastroprotection, hypolipidemia, and modulating gut microbiota.
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