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The review reveals that nutritional supplements, particularly fish oils, vitamins, trace elements, and phytochemical extracts, show promising therapeutic potential for Dry Eye Disease management.

2024 Frontiers in Pharmacology Recommendations for nutritional supplements for dry eye disease: current advances Cong Y, Zhang Y, Han Y, Wu Y, Wang D, Zhang B

Systematic Review Dry Eye Omega-3 Fatty Acids

The methodology used in the research paper mainly focuses on evaluating different oral nutritional supplements with varied compositions and dosages, in order to assess their impact on Dry Eye Disease symptoms. These supplements include key components like fish oils, vitamins, trace elements, and extracts from plants, recognized for their potential nutritional value. Emphasizing the role of nutrition in combating ocular surface diseases, the research also emphasizes the imbalance caused by deficiencies in polyunsaturated fatty acids and vitamin insufficiencies, which can lead to ocular issues such as inflammation and oxidative stress.

The results discussion outlines considerable benefits of using these supplements, not only for managing Dry Eye Disease symptoms but also potentially for overall ocular health. It was observed that nutrients in these supplements hold promising therapeutic qualities, presenting new perspectives for supplement combinations in Dry Eye Disease treatment. Beyond the well-known nutrients, it was suggested that exploring novel nutrients could help establish even more effective management strategies for Dry Eye Disease.

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Bruceolic oil emulsion, when combined with androgen antagonists, shows the greatest efficacy in treating prostate cancer amongst Chinese patent medicines.

2024 Medicine Efficacy and safety of Chinese patent medicine in the adjuvant treatment of prostate cancer: A Bayesian network meta-analysis Wang S, Zhang F, Liu J, Qin P

Network Pharmacology Prostate Cancer

A Network Meta-analysis was conducted to review the safety and effectiveness of different Chinese patent medicines in treating prostate cancer. Various databases were systematically searched for randomized controlled trials of Chinese patent medicines until June 1, 2023. The risk of bias in the included studies was assessed using a tool specifically for randomized controlled trials. Main outcome indicators were how effective the medicine was, its impact on Prostate Specific Antigen, and any adverse reaction. Due to varying treatment durations across the studies, Bayesian mesh meta-regression was implemented to investigate the effects of these different courses on efficacy and safety.

The meta-analysis considered 27 articles involving 1885 patients and nine types of Chinese patent medicine. The findings indicated that certain medicines, namely Bruceolic oil emulsion and Compound Kushen injection, showed significant advantages compared to androgen antagonists regarding efficacy and Prostate Specific Antigen level reduction. However, no significant difference was found among all the Chinese patent medicines in terms of adverse reactions. With these findings, it was deduced that the effectiveness of Chinese patent medicines isn't greatly impacted by the duration of treatment and dosage. Overall, the combination of Bruceolic oil emulsion and androgen antagonist emerged as a promising intervention measure.

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Pumpkin seeds are recognised for their medicinal, nutritional, and cosmetic benefits, including anti-diabetic, heart disease prevention, anti-cancer, and antioxidant qualities.

2024 The Natural Products Journal Pumpkin Seeds (Cucurbita spp.) as a Nutraceutical Used In Various Lifestyle Disorders Wal A, Singh MR, Gupta A, Rathore S, Rout RR, Wal P

Review Article Anti-Parasite Anticancer Antioxidant