Oral Health
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Also known as: Oral Disease
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Published research studies are articles that present the findings of original research that has undergone a peer-review process and has been made publicly available in scholarly journals, books or other media.

Exploring the Clinical Applications of Lemongrass Essential Oil: A Scoping Review
2024 Jan 25 Pharmaceuticals Kusuma IY, Perdana MI, Vágvölgyi C, Csupor D, Takó M
Review Article Lemongrass Oil Dandruff Gingivitis Periodontitis LemongrassLemongrass essential oil can effectively treat periodontitis, gingivitis, oral malodour, skin aging, and dandruff, and it is comparable to certain established treatments.

A systematic and comprehensive review on current understanding of the pharmacological actions, molecular mechanisms, and clinical implications of the genus Eucalyptus
2021 Nov Phytomedicine Plus Chandorkar N, Tambe S, Amin P, Madankar C
Eucalyptus species, especially Eucalyptol, demonstrate significant potential in the treatment and management of various diseases, including respiratory disorders, COVID-19, pain, oral health, infectious diseases, and cancer, as supported by preclinical and clinical studies.
Review Article Eucalyptus Molecular Mechanism Clinical Implication Health Benefits Pharmacologic Activity
Impact of Green Tea (Camellia Sinensis) on periodontitis and caries. Systematic review and meta-analysis
2021 Nov Japanese Dental Science Review Mazur M, Ndokaj A, Jedlinski M, Ardan R, Bietolini S, Ottolenghi L
Systematic Review Meta-Analysis Green Tea Oral HealthGreen tea treatment has shown potential in improving oral hygiene and gingival health, and reducing periodontitis and caries.

Efficacy and Safety of Modified Yunu-Jian in Patients with Periodontitis: A Meta-Analysis
2021 Apr 26 Evidence-Based Complementary and Alternative Medicine Yuanyuan Yue, Meng Gao, Yanru Deng, Jiemin Shao, Yingguang Sun
Evidence from the meta-analysis suggested that modified Yunu-Jian (mYJ) appeared to be effective and relatively safe for treating periodontitis.
Meta-Analysis Periodontitis Yu Nu Jian
Evaluation of Morinda citrifolia (noni) fruit extract as a bone regenerative material in the treatment of periodontal intrabony osseous defects: Clinical and cone-beam computed tomography assessment
2021 Jan Journal of the International Society of Physical and Rehabilitation Medicine Sabu BS, Chandrashekar KT, Mishra R, Tripathi VD, Khatri H, Deo A
Randomised Controlled Trial Anti-Inflammatory Periodontitis NoniMorinda citrifolia fruit extract effectively supports bone regeneration and has anti-inflammatory properties in periodontal bone defects.
Research insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.

2024 Pharmaceuticals
Lemongrass essential oil can effectively treat periodontitis, gingivitis, oral malodour, skin aging, and dandruff, and it is comparable to certain established treatments.
Review Article Dandruff Gingivitis Lemongrass Lemongrass Oil Periodontitis
Exploring the Clinical Applications of Lemongrass Essential Oil: A Scoping Review
Kusuma IY, Perdana MI, Vágvölgyi C, Csupor D, Takó M

2021 Japanese Dental Science Review
Green tea treatment has shown potential in improving oral hygiene and gingival health, and reducing periodontitis and caries.
Systematic Review Green Tea
Impact of Green Tea (Camellia Sinensis) on periodontitis and caries. Systematic review and meta-analysis
Mazur M, Ndokaj A, Jedlinski M, Ardan R, Bietolini S, Ottolenghi L

2021 Journal of the International Society of Physical and Rehabilitation Medicine
Morinda citrifolia fruit extract effectively supports bone regeneration and has anti-inflammatory properties in periodontal bone defects.
Randomised Controlled Trial Anti-Inflammatory Noni Periodontitis
Evaluation of Morinda citrifolia (noni) fruit extract as a bone regenerative material in the treatment of periodontal intrabony osseous defects: Clinical and cone-beam computed tomography assessment
Sabu BS, Chandrashekar KT, Mishra R, Tripathi VD, Khatri H, Deo A

2020 Journal of Herbal Medicine
Green tea catechins-containing mouthwash may potentially be a practical alternative to chlorhexidine due to its efficacy in plaque reduction and minimal side effects.
Systematic Review Gingivitis Green Tea
The Effect of Green Tea on plaque and gingival inflammation: A systematic review
Gartenmann SJ, Steppacher SL, von Weydlich Y, Heumann C, Attin T, Schmidlin PR
Review Articles
Review articles summarise and critically evaluate the current state of research on a specific topic or field by synthesising multiple primary research studies.

Exploring the Clinical Applications of Lemongrass Essential Oil: A Scoping Review
2024 Jan 25 Pharmaceuticals Kusuma IY, Perdana MI, Vágvölgyi C, Csupor D, Takó M
Review Article Lemongrass Oil Dandruff Gingivitis Periodontitis LemongrassLemongrass essential oil can effectively treat periodontitis, gingivitis, oral malodour, skin aging, and dandruff, and it is comparable to certain established treatments.

A systematic and comprehensive review on current understanding of the pharmacological actions, molecular mechanisms, and clinical implications of the genus Eucalyptus
2021 Nov Phytomedicine Plus Chandorkar N, Tambe S, Amin P, Madankar C
Eucalyptus species, especially Eucalyptol, demonstrate significant potential in the treatment and management of various diseases, including respiratory disorders, COVID-19, pain, oral health, infectious diseases, and cancer, as supported by preclinical and clinical studies.
Review Article Eucalyptus Molecular Mechanism Clinical Implication Health Benefits Pharmacologic Activity
Impact of Green Tea (Camellia Sinensis) on periodontitis and caries. Systematic review and meta-analysis
2021 Nov Japanese Dental Science Review Mazur M, Ndokaj A, Jedlinski M, Ardan R, Bietolini S, Ottolenghi L
Systematic Review Meta-Analysis Green Tea Oral HealthGreen tea treatment has shown potential in improving oral hygiene and gingival health, and reducing periodontitis and caries.

The Effect of Green Tea on plaque and gingival inflammation: A systematic review
2020 Jun Journal of Herbal Medicine Gartenmann SJ, Steppacher SL, von Weydlich Y, Heumann C, Attin T, Schmidlin PR
Systematic Review Gingivitis Green TeaGreen tea catechins-containing mouthwash may potentially be a practical alternative to chlorhexidine due to its efficacy in plaque reduction and minimal side effects.

An Update on the Health Benefits of Green Tea
2018 Jan 18 Beverages Wanda C. Reygaert
Systematic ReviewAmong the health benefits of green tea are: anticarcinogenic, anti-inflammatory, antimicrobial, and antioxidant properties, and benefits in cardiovascular disease and oral health.
Clinical Trials
Clinical trials are research studies that involve people and are conducted to evaluate the safety and efficacy of new treatments or interventions, such as drugs, medical devices, or behavioural therapies.

Evaluation of Morinda citrifolia (noni) fruit extract as a bone regenerative material in the treatment of periodontal intrabony osseous defects: Clinical and cone-beam computed tomography assessment
2021 Jan Journal of the International Society of Physical and Rehabilitation Medicine Sabu BS, Chandrashekar KT, Mishra R, Tripathi VD, Khatri H, Deo A
Randomised Controlled Trial Anti-Inflammatory Periodontitis NoniMorinda citrifolia fruit extract effectively supports bone regeneration and has anti-inflammatory properties in periodontal bone defects.

Acupuncture for pain, mandibular function and oral health‐related quality of life in patients with masticatory myofascial pain: A randomised controlled trial
2020 Jul 31 Journal of Oral Rehabilitation Salles‐Neto FT, Paula JS, Romero JGAJ, Almeida‐Leite CM
Although acupuncture was effective in pain reduction, non-specific factors may have influenced mandibular function and oral health-related quality of life improvements in both groups, and this needs to be further addressed.
Randomised Controlled TrialStudy Protocols
Published study protocols are detailed plans that outline the objectives, methodology, statistical analyses, and organisation of a research study that have been made publicly available for others to review and use as a reference.
Presentation Slides

Review Article
Lemongrass essential oil can effectively treat periodontitis, gingivitis, oral malodour, skin aging, and dandruff, and it is comparable to certain established treatments.
Kusuma IY, Perdana MI, Vágvölgyi C, Csupor D, Takó M

Systematic Review
Green tea treatment has shown potential in improving oral hygiene and gingival health, and reducing periodontitis and caries.
Mazur M, Ndokaj A, Jedlinski M, Ardan R, Bietolini S, Ottolenghi L

Randomised Controlled Trial
Morinda citrifolia fruit extract effectively supports bone regeneration and has anti-inflammatory properties in periodontal bone defects.
Sabu BS, Chandrashekar KT, Mishra R, Tripathi VD, Khatri H, Deo A

Systematic Review
Green tea catechins-containing mouthwash may potentially be a practical alternative to chlorhexidine due to its efficacy in plaque reduction and minimal side effects.
Gartenmann SJ, Steppacher SL, von Weydlich Y, Heumann C, Attin T, Schmidlin PR

Systematic Review
Among the health benefits of green tea are: anticarcinogenic, anti-inflammatory, antimicrobial, and antioxidant properties, and benefits in cardiovascular disease and oral health.
Wanda C. Reygaert
Executive Summary
Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Oral Health" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.
Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Oral Health" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.
Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Oral Health" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.
A Review Article published in 2024 in the journal Pharmaceuticals found that Lemongrass essential oil can effectively treat periodontitis, gingivitis, oral malodour, skin aging, and dandruff, and it is comparable to certain established treatments. The methodology used in the research followed a scoping review design, which was aimed at identifying, summarizing, and synthesizing existing literature related to the clinical applications of lemongrass essential oil. Three databases, namely PubMed, Web of Science, and Scopus, were utilized, following the PRISMA-ScR guidelines, to find articles published within approximately a 10-year timeframe. The results of the review suggest that patients have received noticeable therapeutic benefits from treatments that were primarily administered oromucosally and topically. It can be deduced that the efficacy of lemongrass essential oil in treating periodontitis, gingivitis, and oral malodour is similar to that of chlorhexidine and doxycycline. Moreover, the oil has demonstrated potential in treating skin conditions such as pityriasis versicolor, preventing skin aging, and having anti-dandruff effects. The diverse range of applications of the oil and its efficacy when compared to established treatments highlight its potential for clinical applications.
A Systematic Review published in 2021 in the journal Japanese Dental Science Review found that Green tea treatment has shown potential in improving oral hygiene and gingival health, and reducing periodontitis and caries. The methodology of this research consisted of systematic literature review focusing on clinical trials that evaluated the impact of green tea on managing periodontitis and caries. Various databases including MedLine (PubMed), Scopus, and the Cochrane Library were utilized for gathering relevant studies. Eighteen suitable studies were selected, encompassing 870 subjects. The results reveal a noticeable positive effect from green tea treatment. This effect was realized in the reduction of gingival index, plaque index, gingival bleeding index and bleeding on probing when compared to a control group. It was also noted that when considered among chlorhexidine control groups, green tea showed a slight negative effect. There was additionally a significant positive effect seen in the reduction of clinical attachment level and probing pocket depth with green tea treatment.
A Randomised Controlled Trial published in 2021 in the journal Journal of the International Society of Physical and Rehabilitation Medicine found that Morinda citrifolia fruit extract effectively supports bone regeneration and has anti-inflammatory properties in periodontal bone defects. This study randomized twenty patients who required periodontal regenerative therapy into two groups - an experimental group and a control group. For the control group, open flap debridement alone was used while in the experimental group, the application of Morinda citrifolia fruit extract was coupled with open flap debridement. Clinical aspects such as the gingival index, probing depth of pockets, and relative attachment level were assessed, along with the quantity of bone fill using cone-beam computed tomography at the beginning and after six months. The use of Morinda citrifolia fruit extract in the experimental group resulted in a significant reduction in probing pocket depth and increase in relative attachment level. Furthermore, the extract promoted a higher rate of bone fill in the experimental group compared with the control group, suggesting efficiency in the treatment of intraosseous defects. Additionally, the extract showcased some anti-inflammatory effects, amplifying its potential therapeutic uses.
A Systematic Review published in 2020 in the journal Journal of Herbal Medicine found that Green tea catechins-containing mouthwash may potentially be a practical alternative to chlorhexidine due to its efficacy in plaque reduction and minimal side effects. The methodology involved an exhaustive literature review of several electronic databases, such as CINAHL, Cochrane Library, MEDLINE, PubMed and Scopus, up until January 2017. This review adhered to the PRISMA criteria, centring the research question around the impact of green tea catechins-containing mouthwash on plaque accumulation and gingival inflammation in patients with gingivitis. Out of the 187 titles identified this way, five were fit for meta-analysis, the subject matter primarily revolving around an Asian population. The results indicated that both green tea and chlorhexidine (CHX) significantly outperformed a placebo in reducing Plaque Index (PI), with no substantial contrast between the CHX and green tea groups, both in terms of the endpoint and the change from the beginning of the study to its conclusion. However, only minor side effects were associated with the green tea mouthwash. Contrarily to chlorhexidine, this aspect might make green tea mouthwash more suitable for prolonged use. Despite some heterogeneity in the data and potential bias risks, green tea mouthwash remains an interesting, viable alternative worth considering.
A Systematic Review published in 2018 in the journal Beverages found that Among the health benefits of green tea are: anticarcinogenic, anti-inflammatory, antimicrobial, and antioxidant properties, and benefits in cardiovascular disease and oral health. Green tea catechins have proved to be very versatile in providing health benefits. This means that there are potential health benefits for everyone in the consumption of green tea. Even moderate amounts of consumption (drinking 1–2 cups of tea per day) may have benefits. It is a very good thing that it is the second most popular beverage worldwide, as the differences in health in a world without green tea might be significant. There is fortunately a wide variety of research being performed using green tea catechins, and we are starting to see many studies performed using human subjects, as it is extremely important that we are able to show the direct benefits to humans. The expansive repertoire of green tea activity in health is important, especially to those people who live where medical assistance is not generally available or affordable.
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