Insights & Discussion
Pomegranate and its by-products, particularly the peel, contain bioactive compounds with potential antimicrobial, anticancer and antiviral properties.
In the methodological approach of the study, a comprehensive review was undertaken to collate information on the bioactive components found within pomegranates and their by-products (aril, seed, and peel). The study emphasized the pomegranate peel's properties owing to its high content of the bioactive compounds. The aim was to elucidate the nutritional and functional aspects of pomegranates, particularly as a functional food.
The results outlined that pomegranates, especially their peel, contain bioactive compounds, including punicalagin, punicalin, ellagic acid, punicic acid, and anthocyanins. Therefore, they have potential functional properties such as antimicrobial, anticancer, and antiviral characteristics. These results suggest that pomegranates could be explored to develop nutraceutical or functional food products due to their profound properties. The peel of the pomegranate, specifically, showcases significant potential for development due to its higher bioactive compound content compared to other parts of the fruit.
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2022 South African Journal of Botany Chrysanthemum, an ornamental genus with considerable medicinal value: A comprehensive review Hadizadeh H, Samiei L, Shakeri A
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The method involved in this research aimed at studying the genus Chrysanthemum through a decade-long review (2010-2020) of scientific evidence, focusing on its therapeutic potential, phytochemistry, and pharmacological activities. Various phytochemical compounds including flavonoids, terpenoids, polysaccharides, and unsaturated fatty acids, which are present in the genus Chrysanthemum, were identified. In addition, the taxonomy, distribution, horticultural, and traditional uses of the genus were also studied.
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Pomegranate juice and its bioactive components may serve as cost-effective, next-generation non-pharmacologic anticancer therapies, particularly against colorectal and prostate cancer.
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Methodology: The present review was undertaken to provide current information on the impact of pomegranate juice and its bioactive elements, critically focusing on the effects on the most common six types of cancer. The inherent polyphenolic compounds of pomegranate, such as ellagitannins and punicalagin, are known to have substantial antioxidant capability which has been evaluated through in vitro and in vivo studies. These compounds' ability to avert free radicals and design metal-chelates in biological tissues have offered a useful basis to extrapolate their impact on various types of cancers.
Discussion of Results: The findings indicate that the antioxidant and anti-inflammatory properties of pomegranate possess significant antimutagenic and antiproliferative activities, which proved to be beneficial in modifying gene expression, moderating cellular mechanisms, and limiting the metastasis of cancerous cells. In addition to this, there are reports from a few clinical trials showing the potential of pomegranate ingredients to prevent and treat cancer, notably colorectal and prostate cancer. It’s been noticed that the pomegranate driven therapies may prove to be a cost-effective alternative to costly chemotherapies which often carry drug resistances and severe side effects. Such therapies could offer lesser side effects, making them potential candidates for future non-pharmacologic anticancer treatments.
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In this study, we delved into the archived scientific research concerning bioactive compounds and their sources, particularly focusing on avocado waste products such as leaves, peels, and seeds. We identified the primary compounds found in these parts to include carotenoids, tocopherols, phytosterols and a group of natural organic structures known as polyphenols.
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In investigating the potency of pomegranates, various parts of the plant, including the fruit juice, peel, arils, flowers and bark, were tested for antimicrobial activities, with significant success found particularly in the utilization of the pomegranate peel. The phytochemical compounds examined in the study, particularly ellagic acid and larger hydrolyzable tannins like punicalagin, exhibited high antimicrobial activity. In some instances, the amalgamation of pomegranate constituents delivered the most benefit.
The results indicate the compelling positive effect of pomegranates on the suppression of oral bacteria. The evidence supporting the antibacterial and antiviral activities of pomegranates against foodborne pathogens and other infectious disease organisms was primarily obtained from in vitro cell-based assays. This prompts the need for further exploration and confirmation of these activities in vivo.
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