Synbiotic pomegranate juice daily consumption for 8 weeks enhances metabolic, oxidative, inflammatory, and blood pressure outcomes in females with Polycystic Ovarian Syndrome.
Randomised Controlled Trial Cardiovascular Disease High Blood Pressure PCOS
In this double-blind randomised study over 8 weeks, participants were given 300ml/day of either plain pomegranate juice, a synbiotic beverage, a synbiotic pomegranate juice, or a placebo beverage. Biochemical measures such as lipid profile, total antioxidant capacity, malondialdehyde, and high sensitivity C-reactive protein, as well as blood pressure were evaluated at the start and the end of the trial.
Participants who consumed pomegranate juice, the synbiotic beverage or the synbiotic pomegranate juice saw positive changes in their lipid profiles, oxidative stress markers, inflammation indicators and blood pressure levels. Specifically, total cholesterol was lower for those who consumed the synbiotic beverage, while bad cholesterol (LDL-c) was reduced in the synbiotic and synbiotic pomegranate juice groups, and good cholesterol levels (HDL-c) were increased in the plain pomegranate juice and the synbiotic pomegranate juice groups. As for oxidative stress and inflammation, malondialdehyde was lower and total antioxidant capacity was increased in the pomegranate juice and synbiotic pomegranate juice groups. High sensitivity C-reactive protein decreased in the pomegranate juice group. Blood pressure was lower among those who consumed both the synbiotic pomegranate juice and plain pomegranate juice compared to those who had the placebo.
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