Insights & Discussion
Green tea extract could be considered a potential agent to attenuate PCOS complications mainly due to its effect on weight loss and glycemic levels.
Current evidence indicates that green tea extract (GTE) supplementation has potential beneficial effects on PCOS. Of 314 articles found in the search, four human studies and four animal studies were included. All studies in humans showed the effects of GTE on weight loss. GTE's effect on decreasing testosterone levels in humans and LH levels in animals were also reported. In addition, increases in FSH and progesterone levels in animal models were observed. Although GTE improved fasting blood sugar and insulin levels, the effect of GTE on inflammatory parameters, such as TNF-alpha and IL-6 and antioxidant status, was limited to animal studies.
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Green tea supplementation can significantly reduce body weight in women with polycystic ovary syndrome, hence potentially beneficial in its clinical management.
2022 Nutrition Research Green tea promotes weight loss in women with polycystic ovary syndrome: Systematic review and meta-analysis Colonetti L, Grande AJ, Toreti IR, Ceretta LB, da Rosa MI, Colonetti T
Meta-Analysis Body Weight Green Tea Obesity
The research carried out was a systematic review of randomized controlled trials that focused on women with polycystic ovary syndrome, examining the effects of green tea supplementation versus a placebo. Relevant studies were sourced from electronic databases such as MEDLINE via PubMed, EMBASE via Elsevier, Cochrane Library, LILACS via BVS, and Web of Science using specific terms related to the illness and green tea. Criteria for the evaluation included effects on body weight, fasting insulin, body mass index, body fat percentage, daily caloric intake, waist and hip circumference, and the waist/hip ratio.
Among the studies considered, there were a total of 169 women, with 85 allocated to the green tea group and 84 to the placebo group. It became apparent that there was a significant reduction in body weight for the group that received green tea supplementation. This leans towards the potential of green tea to be beneficial in the management of this syndrome.
Consumption of green tea enriched with a citrus polyphenol, α-glucosyl hesperidin, can prevent weight gain and reduce body mass index, especially in individuals under 50 years.
2021 Scientific Reports The combined effect of green tea and α-glucosyl hesperidin in preventing obesity: a randomized placebo-controlled clinical trial Yoshitomi R, Yamamoto M, Kumazoe M, Fujimura Y, Yonekura M, Shimamoto Y, et al.
Clinical Study EGCG Green Tea Obesity
The research involved a randomized, placebo-controlled, double-blinded, and parallel-group-designed clinical trial. Sixty healthy Japanese men and women aged between 30 and 75 were included in the study. They were instructed to consume a blend of green tea and α-glucosyl hesperidin (GT-gH). Each dosage contained 178 mg α-glucosyl hesperidin and 146 mg of an active ingredient of green tea, called EGCG. This protocol was followed for 12 weeks. Participants underwent physical, hematological, blood biochemical, and urine examinations to ensure safety.
Discussion of findings showed that the GT-gH mixture played a significant role in weight management. By the end of 12 weeks, participants who consumed the GT-gH mix showed prevention in weight gain and a reduction in body mass index when compared to the control group. The anti-obesity effect was particularly observable in individuals aged below 50. These participants experienced lower levels of triglyceride, body fat percentage, and visceral fat levels, alongside a decrease in body weight, BMI, and blood LDL/HDL ratios.
Green tea consumption notably reduces body weight, body mass index, and body fat, especially in long-term use, at lower dosages, and among overweight individuals with type-2 diabetes.
2020 Complementary Medicine Research Effect of Green Tea on Anthropometric Indices and Body Composition in Patients with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis Asbaghi O, Fouladvand F, Gonzalez MJ, Aghamohammadi V, Choghakhori R, Abbasnezhad A
Systematic Review Anti-Diabetic Green Tea Obesity
In this systematic review and meta-analysis, a comprehensive search was undertaken on Scopus, ISI Web of Science, and PubMed, for articles related to the topic, up until June 2019. To synthesize the data, a meta-analysis was conducted using the random effects model, and an index was employed to assess the levels of inconsistency in the findings.
The assessment of this research involved evaluating eleven eligible articles. Analysis showed that green tea significantly lowered body weight, body mass index, and body fat. Notably, the advantageous effects of green tea were most observable in long-term interventions beyond eight weeks, at doses of green tea equal to or less than 800 mg per day, and among overweight patients. The study underscores the positive role of green tea consumption in improving body composition indicators among type-2 diabetes patients, given these specific conditions.
Daily consumption of coffee and green tea is linked with decreased body mass index, body fat percentage, and cardiovascular risks in middle-aged Japanese women.
2020 Nutrients Daily Coffee and Green Tea Consumption Is Inversely Associated with Body Mass Index, Body Fat Percentage, and Cardio-Ankle Vascular Index in Middle-Aged Japanese Women: A Cross-Sectional Study Yonekura Y, Terauchi M, Hirose A, Odai T, Kato K, Miyasaka N
Body Fat Percentage Body Mass Index Cardio-Ankle Vascular Index
This cross-sectional study was conducted with 232 Japanese women aged 40-65 years who visited the menopause clinic of Tokyo Medical and Dental University Hospital from November 2007 to August 2017. The women's body composition and cardiovascular parameters were assessed using a body composition analyzer and vascular screening system. Furthermore, their coffee and green tea consumption frequency was gauged using a brief-type self-administered diet history questionnaire. The researchers then explored the associations between these variables using multivariate logistic regression.
In terms of results, the study found a negative association between daily coffee consumption and both high body mass index and body fat percentage. Similarly, daily green tea consumption was inversely related to high body fat percentage. The combined daily consumption of coffee and green tea also showed inverse relationships with both body mass index and body fat percentage. Moreover, in pre- and perimenopausal women, daily consumption of both beverages was found to be negatively associated with cardio-ankle vascular index, a measure of cardiovascular risk.
Green tea intake can significantly reduce body weight, body mass index and waist circumference, with the greatest effect seen with lower dosages and shorter treatment durations.
2020 Phytotherapy Research The effect of green tea supplementation on obesity: A systematic review and dose–response meta‐analysis of randomized controlled trials Lin Y, Shi D, Su B, Wei J, Găman MA, Sedanur Macit M, et al.
Systematic Review Green Tea Obesity
In the methodology used for this study, several databases were exhaustively searched from their inception to September 2019. The goal was to identify clinical trials that had explored the influence of green tea supplements on obesity indices in humans. The dosage, type of extract, and duration of the intervention were key factors for the study. The study design incorporated the use of a random-effects model to aggregate the collected data.
In terms of the study's results, they demonstrated notable changes in subjects' obesity indices following the administration of green tea. A significant reduction in body weight and body mass index was observed, which was consistent across all extracted data. The most noticeable change was observed in the reduction of waist circumference in subjects who were administered an equivalent of 800 mg/day of green tea. Also, a more significant reduction in body weight occurred with a green tea dosage of less than 500 mg/day and a treatment duration of 12 weeks. These results affirm the potential use of green tea in improving obesity indices and the study advocates for the inclusion of green tea supplements, combined with a balanced diet and regular exercise, in obesity management strategies.
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