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Research Articles
Published research studies are articles that present the findings of original research that has undergone a peer-review process and has been made publicly available in scholarly journals, books or other media.
Honey Bee Products: Preclinical and Clinical Studies of Their Anti-inflammatory and Immunomodulatory Properties
2022 Jan 03 Frontiers in Nutrition El-Seedi HR, Eid N, Abd El-Wahed AA, Rateb ME, Afifi HS, Algethami AF, et al.
Bee products, including propolis, royal jelly, honey, bee venom, and bee pollen, show potential therapeutic effects in regulating inflammatory mediator production, improving immune response, and acting as anti-inflammatory, immune protective, antioxidant, anti-apoptotic, and antimicrobial agents.
Review Article
N-Chromosome Royal Jelly, Propolis and Bee Pollen Supplementation Improve the Clinical Conditions of COVID-19 Patients: A Randomized Controlled Trial
2022 Jan 08 Traditional and Integrative Medicine Abedini A, Shafaghi S, Ameri Ahmad Z, Javanmardi E, Ghorbani F, Sharif-Kashani B, et al.
In a randomized, open-label, controlled trial involving 50 cases of COVID-19, the intervention group receiving royal jelly, propolis, and bee pollen in addition to conventional treatment showed a more pronounced improvement in functional class compared to the control group. Additionally, the intervention group experienced significantly reduced total symptoms duration and time to return to work. Although these natural supplements are not definitive treatments for COVID-19, they can be considered as adjuvant treatments to limit disease symptoms and virus propagation.
Randomised Controlled Trial Bee Pollen COVID-19
Review on Bee Products as Potential Protective and Therapeutic Agents in Male Reproductive Impairment
2021 Jun 05 Molecules Suleiman JB, Bakar ABA, Mohamed M
Bee products such as honey, royal jelly, bee pollen, bee brood, apilarnil, bee bread, bee wax, and bee venom showed positive effects on male reproductive parameters, suggesting their potential as preventive and therapeutic treatments for male sub/infertility.
Review Article Bee Pollen
Apitherapy for Age-Related Skeletal Muscle Dysfunction (Sarcopenia): A Review on the Effects of Royal Jelly, Propolis, and Bee Pollen
2020 Sep 25 Foods Ali AM, Kunugi H
Bee products, rich in antioxidants and with versatile pharmacological activities, have shown varying positive effects on muscle mass, strength, and function in laboratory animals and limited human studies. Potential mechanisms include reducing inflammation and oxidative damage, promoting metabolic regulation, enhancing satellite stem cell responsiveness, improving muscular blood supply, inhibiting catabolic genes, and promoting peripheral neuronal regeneration.
Review Article Bee Pollen SarcopeniaUsing Bee Products for the Prevention and Treatment of Oral Mucositis Induced by Cancer Treatment
2019 Aug 21 Molecules Münstedt K, Männle H
Honey, propolis, and royal jelly show evidence for their effectiveness in preventing and treating oral mucositis resulting from chemotherapy or radiotherapy, with potential integration into a comprehensive approach alongside established concepts like oral care, oral cryotherapy, topical vitamin E, and low-level-laser therapy. However, the quality of existing meta-analyses is generally low, and further studies, especially on combinations of various strategies, are needed.
Review Article Meta-AnalysisResearch Insights
Insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.
Honeybee products like honey, propolis, and royal jelly have demonstrated potential benefits in treating metabolic diseases, cancers, and other illness types.
2017 Oxidative Medicine and Cellular Longevity Honey, Propolis, and Royal Jelly: A Comprehensive Review of Their Biological Actions and Health Benefits Pasupuleti VR, Sammugam L, Ramesh N, Gan SH
Review Article Cancer Honey Metabolic Syndrome
The research reviewed the effects and mechanisms of honey, propolis, and royal jelly on various health conditions. Their uses in correlation to metabolic diseases and different types of cancers were meticulously explored. Honey was examined for its microbial inhibiting and wound healing properties and its role in treating other diseases.
The study found that honey demonstrated potential benefits such as microbial inhibition, wound healing, and effects on other diseases. Propolis was reported to have various health benefits related to gastrointestinal disorders, allergies, and issues related to gynecology, oral health, and dermatology. Royal jelly displayed protective effects on reproductive health, neurodegenerative disorders, wound healing, and aging. While these were potential benefits and effects elucidated, the specific mechanisms of action remain undetermined.
Review Articles
Review articles summarise and critically evaluate the current state of research on a specific topic or field by synthesising multiple primary research studies.
Honey Bee Products: Preclinical and Clinical Studies of Their Anti-inflammatory and Immunomodulatory Properties
2022 Jan 03 Frontiers in Nutrition El-Seedi HR, Eid N, Abd El-Wahed AA, Rateb ME, Afifi HS, Algethami AF, et al.
Bee products, including propolis, royal jelly, honey, bee venom, and bee pollen, show potential therapeutic effects in regulating inflammatory mediator production, improving immune response, and acting as anti-inflammatory, immune protective, antioxidant, anti-apoptotic, and antimicrobial agents.
Review ArticleReview on Bee Products as Potential Protective and Therapeutic Agents in Male Reproductive Impairment
2021 Jun 05 Molecules Suleiman JB, Bakar ABA, Mohamed M
Bee products such as honey, royal jelly, bee pollen, bee brood, apilarnil, bee bread, bee wax, and bee venom showed positive effects on male reproductive parameters, suggesting their potential as preventive and therapeutic treatments for male sub/infertility.
Review Article Bee PollenApitherapy for Age-Related Skeletal Muscle Dysfunction (Sarcopenia): A Review on the Effects of Royal Jelly, Propolis, and Bee Pollen
2020 Sep 25 Foods Ali AM, Kunugi H
Bee products, rich in antioxidants and with versatile pharmacological activities, have shown varying positive effects on muscle mass, strength, and function in laboratory animals and limited human studies. Potential mechanisms include reducing inflammation and oxidative damage, promoting metabolic regulation, enhancing satellite stem cell responsiveness, improving muscular blood supply, inhibiting catabolic genes, and promoting peripheral neuronal regeneration.
Review Article Bee Pollen SarcopeniaUsing Bee Products for the Prevention and Treatment of Oral Mucositis Induced by Cancer Treatment
2019 Aug 21 Molecules Münstedt K, Männle H
Honey, propolis, and royal jelly show evidence for their effectiveness in preventing and treating oral mucositis resulting from chemotherapy or radiotherapy, with potential integration into a comprehensive approach alongside established concepts like oral care, oral cryotherapy, topical vitamin E, and low-level-laser therapy. However, the quality of existing meta-analyses is generally low, and further studies, especially on combinations of various strategies, are needed.
Review Article Meta-AnalysisAntioxidant Potential of Propolis, Bee Pollen, and Royal Jelly: Possible Medical Application
2018 Jan Oxidative Medicine and Cellular Longevity Kocot J, Kiełczykowska M, Luchowska-Kocot D, Kurzepa J, Musik I
Bee products, including propolis, bee pollen, and royal jelly, exhibit significant antioxidant capacity, making them potential candidates for therapeutic applications against diseases associated with oxidative stress. The review emphasizes the importance of understanding the mechanisms underlying the antioxidant properties of these bee products and discusses factors influencing their composition, such as bee species, plant origin, geographic location, seasonality, and extraction solutions.
Systematic Review Review Article Bee PollenClinical Trials
Clinical trials are research studies that involve people and are conducted to evaluate the safety and efficacy of new treatments or interventions, such as drugs, medical devices, or behavioural therapies.
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Honeybee products like honey, propolis, and royal jelly have demonstrated potential benefits in treating metabolic diseases, cancers, and other illness types.
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