Plant-Based Diet
Also known as: Vegan Diet
Recent Insights
Changes in gut microbiome associated with a low-fat, vegan diet and cooked soybeans may reduce the frequency and severity of postmenopausal hot flashes.
Gut Microbiota Hot Flushes Low Fat Diet
Fasting followed by a plant-based diet and a standard diet both positively affected rheumatoid arthritis disease activity and cardiovascular risk factors, without discernible differences.
Cardiovascular Risk Plant-Based Diet Rheumatoid Arthritis
A diet low in fat, vegan, and inclusive of daily cooked soybeans significantly reduces the frequency and severity of hot flashes in postmenopausal women.
Hot Flushes Low Fat Diet Menopause
Fasting followed by a plant-based diet positively impacts disease activity and cardiovascular risk factors in rheumatoid arthritis patients.
Intermittent Fasting Plant-Based Diet Rheumatoid Arthritis
Related Topics
Research Articles
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A dietary intervention for postmenopausal hot flashes: A potential role of gut microbiome. An exploratory analysis
2023 Dec Complementary Therapies in Medicine Kahleova H, Holtz DN, Strom N, La Reau A, Kolipaka S, Schmidt N, et al.
Randomised Controlled Trial Low Fat Diet Gut Microbiota Plant-Based Diet Hot Flushes SoybeanChanges in gut microbiome associated with a low-fat, vegan diet and cooked soybeans may reduce the frequency and severity of postmenopausal hot flashes.
Exploring the Potential Benefits of Natural Calcium-Rich Mineral Waters for Health and Wellness: A Systematic Review
2023 Jul 13 Nutrients Pop MS, Cheregi DC, Onose G, Munteanu C, Popescu C, Rotariu M, et al.
Systematic Review Meta-Analysis Cardiovascular Disease High Blood Pressure Mineral Water Natural Calcium-rich mineral water Bone Health CalciumNatural calcium-rich mineral waters offer a bioavailable calcium source, beneficial for bone health, cardiovascular function, weight management, and overall well-being.
To eat or not to eat—an exploratory randomized controlled trial on fasting and plant-based diet in rheumatoid arthritis (NutriFast-Study)
2022 Nov 02 Frontiers in Nutrition Hartmann AM, Dell'Oro M, Spoo M, Fischer JM, Steckhan N, Jeitler M, et al.
Randomised Controlled Trial Plant-Based Diet Cardiovascular Risk Rheumatoid ArthritisFasting followed by a plant-based diet and a standard diet both positively affected rheumatoid arthritis disease activity and cardiovascular risk factors, without discernible differences.
A dietary intervention for vasomotor symptoms of menopause: a randomized, controlled trial
2022 Oct 16 Menopause Barnard ND, Kahleova H, Holtz DN, Znayenko-Miller T, Sutton M, Holubkov R, et al.
Randomised Controlled Trial Plant-Based Diet Hot Flushes Low Fat Diet Menopause SoybeanA diet low in fat, vegan, and inclusive of daily cooked soybeans significantly reduces the frequency and severity of hot flashes in postmenopausal women.
POS0583 RHEUMATOID ARTHRITIS BENEFITS FROM FASTING AND PLANT-BASED DIET: AN EXPLORATORY RANDOMIZED CONTROLLED TRIAL (NUTRIFAST)
2022 May 23 Annals of the Rheumatic Diseases Hartmann AM, Kandil FI, Steckhan N, Häupl T, Kessler CS, Michalsen A, et al.
Randomised Controlled Trial Plant-Based Diet Intermittent Fasting Rheumatoid ArthritisFasting followed by a plant-based diet positively impacts disease activity and cardiovascular risk factors in rheumatoid arthritis patients.
Research Insights
Insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.
Changes in gut microbiome associated with a low-fat, vegan diet and cooked soybeans may reduce the frequency and severity of postmenopausal hot flashes.
2023 Complementary Therapies in Medicine A dietary intervention for postmenopausal hot flashes: A potential role of gut microbiome. An exploratory analysis Kahleova H, Holtz DN, Strom N, La Reau A, Kolipaka S, Schmidt N, et al.
Randomised Controlled Trial Gut Microbiota Hot Flushes Low Fat Diet
In this study, 84 postmenopausal women experiencing two or more moderate-to-severe hot flashes daily were randomly assigned to a low-fat, vegan diet with daily cooked soybeans or allowed to maintain their usual diet. Over a 12-week period, the frequency and severity of hot flashes were tracked using a mobile application. In 11 women from the group, gut microbiome was analyzed at the start and after 12 weeks of the dietary intervention, using deep shotgun metagenomic sequencing.
The women who underwent gut microbiome testing experienced a substantial decrease in total hot flashes during the dietary intervention, and severe hot flashes disappeared entirely in this group. Alpha and beta diversity within the microbiome showed no significant difference in the intervention group between baseline and the end of the 12 weeks. Interestingly, adjustments in the relative abundance of certain bacterial strains, notably Porphyromonas and Prevotella corporis, were linked with the reduction in severe day hot flashes, while changes in the relative abundance of Clostridium asparagiforme were associated with a reduction in total severe hot flashes and severe night hot flashes.
Natural calcium-rich mineral waters offer a bioavailable calcium source, beneficial for bone health, cardiovascular function, weight management, and overall well-being.
2023 Nutrients Exploring the Potential Benefits of Natural Calcium-Rich Mineral Waters for Health and Wellness: A Systematic Review Pop MS, Cheregi DC, Onose G, Munteanu C, Popescu C, Rotariu M, et al.
Systematic Review Bone Health Calcium Cardiovascular Disease
This systematic review analyzed peer-reviewed articles, clinical trials, and experimental studies from the past decade. It focused on the health benefits of calcium-rich mineral waters, especially for individuals with lactose intolerance or on plant-based diets. The review process assessed the contribution of these waters to daily calcium intake and their bioavailability compared to other calcium sources.
The review found that natural mineral waters high in calcium can significantly enhance calcium intake, with improved absorption rates. These waters show promise in promoting bone health and cardiovascular function, including potential reductions in blood pressure and cardiovascular disease risk. Some evidence suggests benefits in weight management. However, the review highlighted the need for further research on interactions with other dietary components, effects on specific health conditions, and long-term consumption impacts. Despite these gaps, calcium-rich mineral waters are recognized as a valuable dietary calcium source for a diverse population.
Fasting followed by a plant-based diet and a standard diet both positively affected rheumatoid arthritis disease activity and cardiovascular risk factors, without discernible differences.
2022 Frontiers in Nutrition To eat or not to eat—an exploratory randomized controlled trial on fasting and plant-based diet in rheumatoid arthritis (NutriFast-Study) Hartmann AM, Dell'Oro M, Spoo M, Fischer JM, Steckhan N, Jeitler M, et al.
Randomised Controlled Trial Cardiovascular Risk Rheumatoid Arthritis
In this research, 53 rheumatoid arthritis patients were divided into two equal groups. One group underwent a 7-day fast and thereafter followed an 11-week plant-based diet. The second group adhered to a 12-week standard diet based on the dietary recommendations of the German society for nutrition. The main metric of comparison between the two groups was the change from baseline to 12 weeks on the Health Assessment Questionnaire Disability Index.
The research showed that the fasting group noted an early improvement by day 7 and remained stable over 12 weeks. Meanwhile, the standard diet group showed slower but positive enhancements at 6 and 12 weeks. Furthermore, both dietary methods contributed to an improvement in disease activity scores of all the patients by week 12. Also, an advancement in cardiovascular risk factors, notably weight loss, was more prominent in the fasting group than the standard diet group.
A diet low in fat, vegan, and inclusive of daily cooked soybeans significantly reduces the frequency and severity of hot flashes in postmenopausal women.
2022 Menopause A dietary intervention for vasomotor symptoms of menopause: a randomized, controlled trial Barnard ND, Kahleova H, Holtz DN, Znayenko-Miller T, Sutton M, Holubkov R, et al.
Randomised Controlled Trial Hot Flushes Low Fat Diet Menopause
The methodology used involved the selection of 84 postmenopausal women who reported at least two moderate-to-severe hot flashes. These women were randomly divided into two cohorts, one prescribed the dietary intervention of a low-fat, vegan diet coupled with daily servings of cooked soybeans and a control group which did not alter their diet. Over a 12-week period, a mobile application was used to track hot flashes in terms of frequency and severity. Further, the participants’ vasomotor, psychosocial, physical, and sexual symptoms were assessed using the Menopause-Specific Quality of Life questionnaire. In some participants, the presence of urinary equol, a compound formed in the gut after consuming soy, was measured following the intake of the specified amount of soybeans for 3 days.
In discussing the results, a remarkable decrease was noted in the frequency and severity of hot flashes experienced by the group assigned the dietary intervention versus those in the control group. In addition, after 12 weeks, half of the participants adhering to the vegan diet and daily soy intake reported complete cessation of moderate-to-severe hot flashes. Furthermore, notable decreases were reported in the intervention group in menopause-specific quality of life domains including vasomotor, physical, and sexual. Neither the season nor the participant's ability to produce equol played a notable role in these improvements.
Fasting followed by a plant-based diet positively impacts disease activity and cardiovascular risk factors in rheumatoid arthritis patients.
2022 Annals of the Rheumatic Diseases POS0583 RHEUMATOID ARTHRITIS BENEFITS FROM FASTING AND PLANT-BASED DIET: AN EXPLORATORY RANDOMIZED CONTROLLED TRIAL (NUTRIFAST) Hartmann AM, Kandil FI, Steckhan N, Häupl T, Kessler CS, Michalsen A, et al.
Randomised Controlled Trial Intermittent Fasting Rheumatoid Arthritis
In the pilot study, patients with rheumatoid arthritis (RA) were split into two groups: one underwent a 7-day fast (consuming no more than 250 calories per day), followed by 11 weeks of a plant-based diet; the other was provided with conventional nutritional counseling according to the recommendations of the German Society for Nutrition for a total of 12 weeks. Disease activity and treatment responses were evaluated at the beginning of the experiment, day 7, week 6, and week 12.
The results showed improvements in disease activity in both the fasting and conventional nutritional counseling groups. Noteworthy was the fact that the fasting group started showing improvements by day 7 as opposed to week 6 in the conventional group. Additionally, cardiovascular risk factors, such as weight and total cholesterol levels, showed more marked improvement in the fasting group compared to the conventional group. These improvements were found to be independent of any antibody status, intervention delivery method, or previous eating habits.
Review Articles
Review articles summarise and critically evaluate the current state of research on a specific topic or field by synthesising multiple primary research studies.
Clinical Trials
Clinical trials are research studies that involve people and are conducted to evaluate the safety and efficacy of new treatments or interventions, such as drugs, medical devices, or behavioural therapies.
A dietary intervention for postmenopausal hot flashes: A potential role of gut microbiome. An exploratory analysis
2023 Dec Complementary Therapies in Medicine Kahleova H, Holtz DN, Strom N, La Reau A, Kolipaka S, Schmidt N, et al.
Randomised Controlled Trial Low Fat Diet Gut Microbiota Plant-Based Diet Hot Flushes SoybeanChanges in gut microbiome associated with a low-fat, vegan diet and cooked soybeans may reduce the frequency and severity of postmenopausal hot flashes.
To eat or not to eat—an exploratory randomized controlled trial on fasting and plant-based diet in rheumatoid arthritis (NutriFast-Study)
2022 Nov 02 Frontiers in Nutrition Hartmann AM, Dell'Oro M, Spoo M, Fischer JM, Steckhan N, Jeitler M, et al.
Randomised Controlled Trial Plant-Based Diet Cardiovascular Risk Rheumatoid ArthritisFasting followed by a plant-based diet and a standard diet both positively affected rheumatoid arthritis disease activity and cardiovascular risk factors, without discernible differences.
A dietary intervention for vasomotor symptoms of menopause: a randomized, controlled trial
2022 Oct 16 Menopause Barnard ND, Kahleova H, Holtz DN, Znayenko-Miller T, Sutton M, Holubkov R, et al.
Randomised Controlled Trial Plant-Based Diet Hot Flushes Low Fat Diet Menopause SoybeanA diet low in fat, vegan, and inclusive of daily cooked soybeans significantly reduces the frequency and severity of hot flashes in postmenopausal women.
POS0583 RHEUMATOID ARTHRITIS BENEFITS FROM FASTING AND PLANT-BASED DIET: AN EXPLORATORY RANDOMIZED CONTROLLED TRIAL (NUTRIFAST)
2022 May 23 Annals of the Rheumatic Diseases Hartmann AM, Kandil FI, Steckhan N, Häupl T, Kessler CS, Michalsen A, et al.
Randomised Controlled Trial Plant-Based Diet Intermittent Fasting Rheumatoid ArthritisFasting followed by a plant-based diet positively impacts disease activity and cardiovascular risk factors in rheumatoid arthritis patients.
Study Protocols
Published study protocols are detailed plans that outline the objectives, methodology, statistical analyses, and organisation of a research study that have been made publicly available for others to review and use as a reference.
Presentation Slides
Randomised Controlled Trial
Changes in gut microbiome associated with a low-fat, vegan diet and cooked soybeans may reduce the frequency and severity of postmenopausal hot flashes.
Kahleova H, Holtz DN, Strom N, La Reau A, Kolipaka S, Schmidt N, Hata E, Znayenko-Miller T, Holubkov R, Barnard ND
Systematic Review
Natural calcium-rich mineral waters offer a bioavailable calcium source, beneficial for bone health, cardiovascular function, weight management, and overall well-being.
Pop MS, Cheregi DC, Onose G, Munteanu C, Popescu C, Rotariu M, Turnea MA, Dograru G, Ionescu EV, Oprea D, Iliescu MG, Minea M, Stanciu LE, Silișteanu SC, Oprea C
Randomised Controlled Trial
Fasting followed by a plant-based diet and a standard diet both positively affected rheumatoid arthritis disease activity and cardiovascular risk factors, without discernible differences.
Hartmann AM, Dell'Oro M, Spoo M, Fischer JM, Steckhan N, Jeitler M, Häupl T, Kandil FI, Michalsen A, Koppold-Liebscher DA, Kessler CS
Randomised Controlled Trial
A diet low in fat, vegan, and inclusive of daily cooked soybeans significantly reduces the frequency and severity of hot flashes in postmenopausal women.
Barnard ND, Kahleova H, Holtz DN, Znayenko-Miller T, Sutton M, Holubkov R, Zhao X, Galandi S, Setchell KDR
Randomised Controlled Trial
Fasting followed by a plant-based diet positively impacts disease activity and cardiovascular risk factors in rheumatoid arthritis patients.
Hartmann AM, Kandil FI, Steckhan N, Häupl T, Kessler CS, Michalsen A, Koppold-Liebscher DA
Executive Summary
Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Plant-Based Diet" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.
Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Plant-Based Diet" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.
Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Plant-Based Diet" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.
A Randomised Controlled Trial published in 2023 in the journal Complementary Therapies in Medicine found that Changes in gut microbiome associated with a low-fat, vegan diet and cooked soybeans may reduce the frequency and severity of postmenopausal hot flashes. In this study, 84 postmenopausal women experiencing two or more moderate-to-severe hot flashes daily were randomly assigned to a low-fat, vegan diet with daily cooked soybeans or allowed to maintain their usual diet. Over a 12-week period, the frequency and severity of hot flashes were tracked using a mobile application. In 11 women from the group, gut microbiome was analyzed at the start and after 12 weeks of the dietary intervention, using deep shotgun metagenomic sequencing. The women who underwent gut microbiome testing experienced a substantial decrease in total hot flashes during the dietary intervention, and severe hot flashes disappeared entirely in this group. Alpha and beta diversity within the microbiome showed no significant difference in the intervention group between baseline and the end of the 12 weeks. Interestingly, adjustments in the relative abundance of certain bacterial strains, notably Porphyromonas and Prevotella corporis, were linked with the reduction in severe day hot flashes, while changes in the relative abundance of Clostridium asparagiforme were associated with a reduction in total severe hot flashes and severe night hot flashes.
A Systematic Review published in 2023 in the journal Nutrients found that Natural calcium-rich mineral waters offer a bioavailable calcium source, beneficial for bone health, cardiovascular function, weight management, and overall well-being. This systematic review analyzed peer-reviewed articles, clinical trials, and experimental studies from the past decade. It focused on the health benefits of calcium-rich mineral waters, especially for individuals with lactose intolerance or on plant-based diets. The review process assessed the contribution of these waters to daily calcium intake and their bioavailability compared to other calcium sources. The review found that natural mineral waters high in calcium can significantly enhance calcium intake, with improved absorption rates. These waters show promise in promoting bone health and cardiovascular function, including potential reductions in blood pressure and cardiovascular disease risk. Some evidence suggests benefits in weight management. However, the review highlighted the need for further research on interactions with other dietary components, effects on specific health conditions, and long-term consumption impacts. Despite these gaps, calcium-rich mineral waters are recognized as a valuable dietary calcium source for a diverse population.
A Randomised Controlled Trial published in 2022 in the journal Frontiers in Nutrition found that Fasting followed by a plant-based diet and a standard diet both positively affected rheumatoid arthritis disease activity and cardiovascular risk factors, without discernible differences. In this research, 53 rheumatoid arthritis patients were divided into two equal groups. One group underwent a 7-day fast and thereafter followed an 11-week plant-based diet. The second group adhered to a 12-week standard diet based on the dietary recommendations of the German society for nutrition. The main metric of comparison between the two groups was the change from baseline to 12 weeks on the Health Assessment Questionnaire Disability Index. The research showed that the fasting group noted an early improvement by day 7 and remained stable over 12 weeks. Meanwhile, the standard diet group showed slower but positive enhancements at 6 and 12 weeks. Furthermore, both dietary methods contributed to an improvement in disease activity scores of all the patients by week 12. Also, an advancement in cardiovascular risk factors, notably weight loss, was more prominent in the fasting group than the standard diet group.
A Randomised Controlled Trial published in 2022 in the journal Menopause found that A diet low in fat, vegan, and inclusive of daily cooked soybeans significantly reduces the frequency and severity of hot flashes in postmenopausal women. The methodology used involved the selection of 84 postmenopausal women who reported at least two moderate-to-severe hot flashes. These women were randomly divided into two cohorts, one prescribed the dietary intervention of a low-fat, vegan diet coupled with daily servings of cooked soybeans and a control group which did not alter their diet. Over a 12-week period, a mobile application was used to track hot flashes in terms of frequency and severity. Further, the participants’ vasomotor, psychosocial, physical, and sexual symptoms were assessed using the Menopause-Specific Quality of Life questionnaire. In some participants, the presence of urinary equol, a compound formed in the gut after consuming soy, was measured following the intake of the specified amount of soybeans for 3 days. In discussing the results, a remarkable decrease was noted in the frequency and severity of hot flashes experienced by the group assigned the dietary intervention versus those in the control group. In addition, after 12 weeks, half of the participants adhering to the vegan diet and daily soy intake reported complete cessation of moderate-to-severe hot flashes. Furthermore, notable decreases were reported in the intervention group in menopause-specific quality of life domains including vasomotor, physical, and sexual. Neither the season nor the participant's ability to produce equol played a notable role in these improvements.
A Randomised Controlled Trial published in 2022 in the journal Annals of the Rheumatic Diseases found that Fasting followed by a plant-based diet positively impacts disease activity and cardiovascular risk factors in rheumatoid arthritis patients. In the pilot study, patients with rheumatoid arthritis (RA) were split into two groups: one underwent a 7-day fast (consuming no more than 250 calories per day), followed by 11 weeks of a plant-based diet; the other was provided with conventional nutritional counseling according to the recommendations of the German Society for Nutrition for a total of 12 weeks. Disease activity and treatment responses were evaluated at the beginning of the experiment, day 7, week 6, and week 12. The results showed improvements in disease activity in both the fasting and conventional nutritional counseling groups. Noteworthy was the fact that the fasting group started showing improvements by day 7 as opposed to week 6 in the conventional group. Additionally, cardiovascular risk factors, such as weight and total cholesterol levels, showed more marked improvement in the fasting group compared to the conventional group. These improvements were found to be independent of any antibody status, intervention delivery method, or previous eating habits.
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